Experience

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  Tessa Therapeutics Ltd

  • Singapore

  • Executive, Lab Management

    • Jan 2018 - Jan 2022
    • Singapore

    • Responsible for all laboratory procurement • Work with researchers and plan annual spend for common lab wares• Put up Invitation to Quote (ITQ)/GeBIZ Tender for laboratory equipment purchases and managing vendors to ensure timely submission and delivery• Represent the lab to plan new laboratory facilities and space; working internally with Tessa and ASTAR to ensure compliance and safety guidelines are met• Monitor equipment operations/ASTAR equipment adoption: plan adhoc/annual preventive maintenance and organizing engineer’s visits• Manage consumables database, receive all orders and manage goods movement• Maintain Safety Data Sheets (SDS) and Risk Assessments (RA) database, and the labeling of all chemical and hazardous substances• Act as Safety Officer for the lab – conducting monthly safety inspections, ad hoc safety checks and rectification• Plan lab duties and inventory checklist

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  Novartis Institutes for Tropical Diseases

  • Singapore

  • Scientist 1

    • May 2004 - Mar 2017
    • Singapore

    • Support the drug discovery activities for Dengue, Tuberculosis and Malaria projects through target compounds synthesis, isolation and characterization at hit to lead, lead optimization and CSP selection stage • Explore and develop synthetic routes and synthetic strategies to improve existing synthetic procedures applicable for large scale synthesis • Troubleshoot reactions and execute multistep reaction sequences by applying modern organic synthetic methods • Contribute ideas for new molecules based on Structural- Activity Relationship (SAR) and Structural- Pharmacokinetic Relationship (SPR) analysis together with in-vitro and in-vivo data analysis• Perform small to moderate scale synthesis and purification for fragment and structure-based drug design, compound library and multi-parallel compound synthesis design• Proficient in mining chemical and other scientific literature using SciFinder and Reaxys

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  Merck KGaA, Darmstadt, Germany

  • Darmstadt, Germany

  • Internship (Pigment R&D Cosmetics Division)

    • May 2003 - Jan 2004
    • Darmstadt, Germany

    • Performed plant extraction, isolation and identification of active compounds in perennial and medicinal plants. • Synthesized new derivatives of active ingredients via chemical and enzymatic transformation for cosmetics application

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  ECO Industrial Environmental Engineering Pte. Ltd.

  • Singapore

  • Senior Chemist/Quality Executive

    • Feb 2001 - Jun 2002
    • Singapore

    • Managed the operation of analytical service laboratory to ensure compliance with the requirement of ISO/IEC 17025 and SAC-SINGLAS• Performed maintenance and calibration of laboratory instruments and equipment.• Responsible for the documentation and implementation of SAC-SINGLAS Quality System and ISO 14000 Environmental System. • Monitored the QC activities of sulfuric acid and solvent recovery processes.• Provided technical support to physical and chemical operation by conducting bench test and recommending treatment method • Trained as Internal Auditor for ISO9000 and ISO14000

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  ECO Special Waste Management Pte. Ltd.

  • Singapore

  • Incineration Chemist

    • Mar 1999 - Jan 2001
    • Singapore

    • Performed finger print test to monitor incoming incinerator waste and to ensure compatibility of pre-treatment waste before incineration. • Responsible for the environmental monitoring on sewer and watercourse discharges

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  Guan Soon Heng Edible Oil Sdn. Bhd.

  • Perak, Malaysia

  • QC Chemist

    • Jun 1997 - Jan 1999
    • Perak, Malaysia

    • Responsible for day to day QC laboratory activities to ensure all incoming crude oil and processed oil fulfilled the standard requirement.• Handled the documentation and implementation of ISO9002 Quality System. • Liaised with internal and external parties related to quality matters