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Vidya Balagopal profile image

Vidya Balagopal

Scientist at St. Jude Children's Research Hospital
Intro Book
Vidya Balagopal, a seasoned scientist with a strong educational background in Molecular Biology, holds expertise in high-throughput sequencing, gene fusion detection, and molecular barcoding, with 9 years of experience in academia and research institutions.
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Location
Greater Chicago Area, US
Languages
  • English Native or bilingual proficiency
  • Malayalam Native or bilingual proficiency
  • HINDI Native or bilingual proficiency
  • Tamil Limited working proficiency
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Bio

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Vidya Balagopal is a seasoned molecular biologist with expertise in next-generation sequencing and gene expression analysis. At St. Jude Children's Research Hospital, she designs and develops NGS sequencing assays for pediatric cancer detection, and has a strong track record of publishing research on high-throughput sequencing and RNA stability elements. Vidya holds a Doctor of Philosophy in Molecular Biology from the University of Arizona and a Master's degree in Genetics and Biotechnology from the Central Institute of Fisheries Education, Mumbai. She is proficient in multiple languages, including English, Malayalam, Hindi, and Tamil. As a Translational Genomics Scientist at the University of Chicago, Vidya developed and validated clinical tests for gene fusion detection in cancers using RNA-seq and hybrid capture. Her work has been recognized through various teaching and research positions, including Instructor at Johns Hopkins University and Postdoctoral Researcher at the University of Connecticut Health Center. Vidya's expertise in molecular biology and bioinformatics has been demonstrated through her research on novel RNA stability elements, mRNA degradation, and high-throughput sequencing. Throughout her career, Vidya has demonstrated a strong ability to design and develop novel sequencing assays, analyze complex biological data, and communicate her findings through publications and presentations. Her expertise in molecular biology and bioinformatics has been recognized through various teaching and research positions, and she continues to contribute to the field through her research and publications.

Experience

  • St. Jude Children's Research Hospital
    • Scientist
      • Sep 2021 - Present

      • Design and development of NGS sequencing assays for detection of bio-markers for pediatric cancers.• High throughput sequencing based detection of MRD in Leukemia

  • University of Chicago
    • Greater Chicago Area
    • Translational Genomics Scientist
      • Nov 2017 - Sep 2021
      • Greater Chicago Area

      • Developed and validated clinical test for gene fusion detection in cancers using RNA-seq and hybrid capture.• Development and optimization of molecular barcoding based DNA sequencing assays for detection of very low variant allele frequency (0.1-0.01%).• Development of cell free DNA based NGS a...

  • Johns Hopkins University
    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Fellow
      • Jun 2015 - Nov 2017

      Designed a high-throughput sequencing based screen to identify novel RNA stability elements in the human genome.Designed, performed and analyzed RNA-seq experiments to identify potential oncogenes in chickencells.Used RNAi and transcriptional pulse-chase to identify mechanism of Nonsense mediated decay in HeLa cells.

    • Instructor
      • Jun 2015 - Nov 2017

      Designed and taught"Genomics: Theory & Practice"( 020.328) Three credit class for upperclassmenDesigned and taught “High-throughput sequencing in Biology” (070.174)---- Intersession & Summer2016Guest Lecture “Genomics” lecture 020.380/650------ Fall 2015
& 2016 Molecular Biology

  • University of Connecticut Health Center
    • Farmington, CT
    • Postdoctoral researcher
      • Dec 2011 - May 2015
      • Farmington, CT

      Designed,implemented and optimized a novel next generation sequencing (NGS) basedtechnique,END-seq, to measure the poly(A) tail length transcriptome-wide in yeast. The assay andbioinformatic analysis can be adapted for use with other organisms.Performed RIP-seq and iCLIP on bicoid protein in earl...

  • University of Umea
    • Visiting Researcher
      • Jun 2011 - Sep 2011
  • The University of Arizona
    • Tucson, AZ
    • Graduate assistant
      • 2004 - 2010
      • Tucson, AZ

      Designed and performed a genetic screen to identify Stm1 as a novel regulator of mRNAdegradation.
 Used northern analysis and microscopy to show Stm1 functions in decay and translation of specificmRNAs.Cloned, expressed and purified Stm1 protein from e.coli and used in vitro translation assays to...

  • University of Arizona
    • Teaching assistant
      • 2004 - 2005

      Molecular Biology 500 level class, Biochemistry 400 level.

Education

  • University of Arizona
  • Central Insititue of fisheries education, Mumbai

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Industry Focus. “Biotechnology.”

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