Experience

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  Zumutor Biologics

  • Bengaluru, Karnataka, India

  • Scientific Manager

    • Nov 2021 - Present
    • Bengaluru, Karnataka, India

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  Syngene International Limited

  • Bengaluru Area, India

  • Research Investigator

    • Nov 2019 - Nov 2021
    • Bengaluru Area, India

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  Massachusetts Institute of Technology

  • Greater Boston Area

  • Postdoctoral Associate

    • Feb 2017 - Oct 2019
    • Greater Boston Area

    My research focuses on the development of peptide inhibitors against intracellular cancer targets such as the pro-survival BCL-2 family proteins and its optimization for intracellular delivery.• Developed potent peptide inhibitors of pro-survival BCL-2 family members with high in vitro efficacy.• Optimized high-throughput assays for characterizing efficacies of the peptide inhibitors.• Collaborating with scientists from academia to develop and test a delivery system involving polymeric nanoparticles for intracellular targeting of the peptide inhibitors.• Collaborating with a research team in industry to test an alternative strategy for intracellular delivery by conjugating the peptide inhibitors to cyclic cell penetrating peptide tags.

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  Rosalind Franklin University of Medicine and Science

  • United States
  • Higher Education
  • 700 & Above Employee

  • Research Associate

    • Oct 2016 - Jan 2017

  • Graduate Research Assistant

    • Sep 2010 - Sep 2016

    My research has been focused on understanding the structural organization of the oligomeric pore formed by the pro-apoptotic BCL-2 family protein, BAK, on the mitochondrial outer membrane. Formation of the BAK apoptotic pore releases cellular constituents into the cytosol activating a cascade of downstream events that ultimately lead to cell death. Dysregulation of this process contribute to various human diseases ranging from cancer, autoimmunity, immunodeficiency to neurodegenerative diseases.The structural and biochemical insights from this study could potentially identify therapeutic agents that can directly regulate this pore forming machinery.

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  University of Calcutta

  • Kolkata, India

  • Research Fellow

    • Dec 2009 - Jul 2010
    • Kolkata, India

    Explored the fluorescence properties of water within the NIR region and analyzed whether the NIR signal of water was affected by the size and geometry of water clusters formed in different systems.

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  Saha Institute of Nuclear Physics

  • Kolkata, India

  • Research Trainee

    • May 2009 - Aug 2009
    • Kolkata, India

    Investigated for hemoglobin interacting cytosolic proteins in normal and thalassemic red blood cell samples.