Bio
Experience
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Crown Bioscience, Inc.
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Beijing City, China
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Director
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Dec 2009 - Present
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Beijing City, China
2009.12 till now (Director) Cancer pharmacology, Crown Biosciences. Inc. Management: Have 6 years of managing experience. Director in Cancer pharmacology in Crown Biosciences Beijing company, be in charge of the team for 6 years, mentor 20 peoples, including technicians and Ph.Ds. Project performance: Lead whole team, performed ~200 preclinical oncology projects per year, achieved ~5,000,000 $ revenue per year. Client service: Whole team served ~60 clients per year. Most of clients are from US and Europe, some from Asia. BD support: Fully support BD, provide timely scientific support, assist BD assign project. Fluent English in oral and written. Host client visit, client audit, AAALAC (The Association for Assessment and Accreditation of Laboratory Animal Care) inspection, Tele-conference, et al. Wide experience on guidance establishing and performing efficacy study on cell line derived cancer animal models, including subcutaneous, orthotopic, systemic xenografts, syngenic models as well as other specific models, executation PK, PD, MTD, and so no. Published four AACR abstracts as first author, attend AACR annual meeting and present posters a few times.
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Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
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Beijing City, China
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Associate Professor
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Oct 2007 - Oct 2008
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Beijing City, China
*Study a potential oncogene (MEA6) which is overexpressed in many types of tumor (including meningioma and glioblastoma). We use specific SiRNA to knock down the potential oncogene in many cell line and establish stable cell line, then we transfer these cells into nude mice and follow tumorgenesis and metastasis. We also use wound healing assay and transwell chamber to detect the tumor character of the gene. Simultaneously, we investigate role of the gene in atherogenesis. This gene was overexpressed or reduced expressing in THP-1. Then the cells were induced differentiation by PMA.
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Northeast Gross Pharmaceutical Factory
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Shenyang, Liaoning, China
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Assistant Engineer
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Jul 1993 - Sep 1996
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Shenyang, Liaoning, China
* I had worked in research institute of Northeast gross pharmaceutical factory (NEGPF), a famous corporation in China after my graduating from university. I take charge for potency test of culture by HPLC, selected seeds and took part in pilot scale fermentation in a 5 litre fermentor.
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Education
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2003 - 2007University of North Carolina at Chapel Hill
Postdoctor, Biology department -
1999 - 2002Institute of Biophysics, Chinese Academy of Sciences
Doctor of Philosophy (Ph.D.), Biochemistry and Molecular Biology -
1996 - 1999Bioengineering Institute, Jinan University, China
Master's degree, Genetic Engineering -
1989 - 1993Liaoning University
Bachelor of Science (B.S.), Biochemistry
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