Experience

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  Wyss Zurich

  • Zurich, Switzerland

  • Research Associate Somagenetix

    • Sep 2020 - Dec 2023
    • Zurich, Switzerland

    Somagenetix is a project which aims to initiate a phase I/II clinical trial of a cell-based gene therapy investigational medicinal product (GTIMP). The GTIMP is intended for the treatment of patients with autosomal recessive chronic granulomatous disease (CGD) caused by p47phox deficiency. - Production of mouse and human cell-based homologous products (test items) used for GLP-compliant animal experiments (Enrichment, culturing, lentiviral transduction and analyses of HSCs in a BSL2 cell culture lab according to GLP/GMP guidelines).- Establishing, troubleshooting and writing the batch records for the GMP-compliant production of genetically modified stem cells, as well as carrying out test runs of the production process. Analysis and choice of instruments and materials to be used in the GMP manufacturing process.- Creation and update of all documents required in connection with GLP and GMP-related activities (equipment qualification, risk analysis and instructions, material specifications and risk analysis, SOPs, protocols, manufacturing batch record, etc.)- Assistance in the implementation of in-process controls.- Establishing and maintaining communication with internal and external service providers.

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  Lonza Netherlands, former PharmaCell

  • Netherlands

  • Biotech Associate

    • Dec 2018 - Aug 2020
    • Netherlands

    - Carry out tissue culture activities for cell therapy, according to established procedures and GMP (Good Manufacturing Practice) rules. - Report and review all required process steps in approved batch records. - Follow GDP (Good Documentation Practice) rules. - Participate in the follow up of deviations and changes (Non-conformances, CAPA). - Generate and revise manufacturing procedures. - Trainer of new employees on the project and on general procedures (Gowning, aseptic behavior, etc).

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  Universiteit Maastricht

  • Maastricht e Região, Holanda

  • Research intern - Master Thesis project

    • Oct 2017 - Jun 2018
    • Maastricht e Região, Holanda

    Internship in the context of my Master Thesis at MERLN Institute for Technology-Inspired Regenerative Medicine. Grade: 18 (18/20)This research project aimed at the production and characterization of 3D additive manufactured polymeric scaffolds containing bioactive inorganic fillers with intercalated antibiotics, as well as at the analysis of the interactions of human mesenchymal stem cells (hMSCs) with these scaffolds.

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  ANDL

  • Leiria Area, Portugal

  • Swimming Referee

    • Oct 2013 - Jul 2017
    • Leiria Area, Portugal

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  Politécnico de Leiria

  • Leiria

  • Bachelor's final project

    • Feb 2015 - Jul 2015
    • Leiria

    Grade: 19 (19/20)• Presented this project at the 7th Portuguese Congress on Biomechanics (CNB2017).Final project of BSc, on the theme "Photopolymerization of Hyaluronic Acid Hydrogels", with the objective of performing the chemical, physical and mechanical characterization of methacrylated hyaluronic acid (MeHA), with photopolymerizable properties. The modification introduced to hyaluronic acid, and in the presence and absence of gelling agents (iota-carrageenan), allowed to obtain IPN (Interpenetrating Polymer Networks) and semi-IPN hydrogels.

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  CDRSP - Centre for Rapid and Sustainable Product Development

  • Leiria e Região, Portugal

  • Research intern

    • Jul 2014 - Jul 2014
    • Leiria e Região, Portugal

    One month extracurricular training, where I was involved in the production of 3D additive manufactured hydrogel scaffolds of calcium alginate, by extrusion of sodium alginate solution, calcium carbonate and D-(+)-gluconic acid δ-lactone (GDL) in the fab@home equipment