Experience

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  Convelo Therapeutics, Inc

  • Cleveland, Ohio, United States

  • Senior Scientist

    • Jul 2022 - Present
    • Cleveland, Ohio, United States

    • Spearheading the in vivo efficacy efforts at Convelo Therapeutics by testing novel small molecule therapeutics targeted towards accelerating remyelination using small animal models of demyelination.

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  The Ohio State University Wexner Medical Center

  • Columbus, Ohio

  • Visiting Scholar

    • Aug 2016 - Jun 2022
    • Columbus, Ohio

    • Established multi-disciplinary collaborations to develop biomaterial strategies that target and overcome the physical barrier created by astrocytes and immune cells that prevents functional recovery after a spinal cord injury.• Designed and characterized a cell culture system that aptly mimics the inflammatory in vivo injury environment to promote translational research.• Evaluated the response of astrocytes and immune cells to our biomaterial interventions in vitro using primary cell cultures.• Translated the in vitro findings to an in vivo setting using rodent models of contusion spinal cord injury.• Secured 2 postdoctoral fellowships to pursue this work and published 5 research articles in reputed journals.

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  Rensselaer Polytechnic Institute

  • Troy, New York

  • Research Associate

    • Jan 2016 - Jun 2022
    • Troy, New York

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  The University of Alabama at Birmingham

  • United States
  • Higher Education
  • 700 & Above Employee

  • Postdoctoral Research Associate

    • Jul 2015 - Dec 2015

    • Used novel genetic sensors to study the changes in the calcium and glutamate dynamics of astrocytes in the presence of water-soluble single-walled carbon nanotubes.

  • Graduate Research Assistant

    • Aug 2010 - Jun 2015

    • Studied the morpho-functional changes in primary astrocytes treated with water-soluble single-walled carbon nanotubes to highlight their potential use as drug delivery vehicles.• Used novel genetic sensors to study the mechanism of action of water-soluble single-walled carbon nanotubes on cultured astrocytes.• Evaluated the effects of single-walled carbon nanotube films on the properties of astrocytes to find a film composition suitable for use as a coating material in brain machine interface applications.• Using transgenic animals, assessed the dependency of the changes induced by solute and film modalities of single-walled carbon nanotubes in astrocytes on the expression of glial fibrillary acidic protein.• Published 6 first author research articles in esteemed peer-reviewed journals and trained 7 students to perform cell culture and histology.

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  Indian Institute of Technology, Kharagpur

  • Kharagpur, West Bengal, India

  • Undergraduate Research Assistant

    • Aug 2006 - Apr 2010
    • Kharagpur, West Bengal, India

    • Cloned, expressed, and purified the two segments of Antheraea mylitta, which are expected to code for Seroin, a structural protein in silk.

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  Friedrich Miescher Laboratory of the Max Planck Society

  • Tuebingen, Germany

  • Intern

    • May 2009 - Jul 2009
    • Tuebingen, Germany

    • Trained an inhouse software QPalma, a tool for short read alignment which takes splice sites into consideration, using the genomic and transcriptomic information of Caenorhabditis elegans.• Quantified the alternative RNA transcripts of Caenorhabditis elegans using quantitative PCR and capillary electrophoresis.

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  Dr. Reddy's Laboratories

  • Hyderabad, India

  • Intern

    • May 2008 - Jul 2008
    • Hyderabad, India

    • Using fed batch strategy, optimized the amount of feed added to the recombinant mammalian Chinese hamster ovary (CHO) cell culture to improve the quality and quantity of the product.