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Leonard Tini is a seasoned bioanalyst with expertise in HPLC, mass spec, and assay development. He has over 20 years of experience in the pharmaceutical industry, including roles at AstraZeneca, Wyeth Pharmaceuticals, and Frontage Laboratories, Inc. He has supervised teams, designed and validated automated assays, and implemented cost-saving measures. Leonard holds a Bachelor of Science degree in Pharmacy from Temple University School of Pharmacy and Philadelphia College of Pharmacy and Science.

Experience

  • Frontage Laboratories, Inc
    • 700 Pennsylvania Drive Exton Pa 19341
    • Manager Metrology
      • Oct 2018 - Present
      • 700 Pennsylvania Drive Exton Pa 19341

  • QPS, LLC
    • Newark, DE 19702
    • Administrator, Mass Spec Services
      • Oct 2012 - Present
      • Newark, DE 19702

      Position includes but is not limited to, calibration and maintenance of 24 mass spec systems including HPLC and UPLC components. Troubleshooting and correction of laboratory issues which could interupt the continuous flow of work produced by laboratory scientists. Position also includes supervision of an assistant as well as the writing and modification of SOP's.

    • Field Service Engineer
      • Jan 2012 - Oct 2012
      • New Jersey

      Responsible for installing, calibration and validation of both wired and wireless technology for FDA compliant monitoring systems, primarily refrigeration. Provide service to government facilities including US Army bases and the NIH.Performed periodic maintenance requiring GLP documentation.

    • Scientist DMPK Discovery
      • Jan 1993 - Oct 2011

      Supervise and train DMPK staff on all of the robotic and mass spec instrumentation. Design, program and validate robotic methods for In Vitro support to all Wilmington Discovery projects. Drug distribution specialist for DMPK. Provide bioanalytical support for problem compounds. Maintenance and calibration of all six mass specs and eight robots.Designed, programmed and validated automated assays for Protein and brain binding( 96 well format), Pgp permeability assay (96 well format), a versatile cyp phenotyping assay, plasma stability (96 well format)Designed templates for all of the above assays ensuring error free results.Designed, in collaboration with Millipore a direct feed, type 1, degassed water system which supplies an continuous degassed water supply to multiple robotic systems using only tap water. This system decreased processing time by 25% and signifacantly improved safety. This instrument is now sold commercially by Millipore.Negotiated with big ticket vendors to reduce prices on repetative purchases and instituted multiple cost saving measures which averaged over $100,000.00 yearly.Programmed a functioning cell feeding system which supported Pgp assay.Designed and fabricated a multipositioned disposable trough system for robots with peltier cooling and electric heating, which greatly improved assay by approximately 25% and allowed multiple assays to run using a common deck view.

    • Scientist
      • Feb 1993 - Sep 2011

    • bioanalytical support
      • Jan 1991 - Jan 1993

      subsequently being hired by AstraZeneca.

    • Owner and Operator
      • Jan 1989 - Jan 1991

      Owner and operator of a small delicatessen. Kept inventory and financial records. Catered many events.

    • Quality Assurance Analyst
      • Oct 1981 - Oct 1986

Education

  • 1980 - 1981
    Temple University School of Pharmacy
    Bachelor of Science, Pharmacy
  • 1976 - 1981
    Philadelphia College of Pharmacy and Science
    BS Pharmacy, Pharmacy

Suggested Services

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Industry Focus. “Pharmaceuticals”

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