Bio
Experience
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Research Specialist
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Sep 2023 - Present
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Singapore
• Developed and optimised ligand binding assay for antibodies according to FDA/EMA and GLP guidelines• Prepared documentation such as SOP, Study Plan, Method Development report for ligand binding assays• Maintained cell lines and subcultured them when required • Performed anti proliferation assays for cell lines using biosimilars and compared their potency rate • Performed 4 paramaters logistic regression data analysis for ligand binding assays and anti proliferation cell based assays using XLSTAT and Graphpad Prism and troubleshooting of the data • Compared various biosimilars using bio-layer interferometry assay by checking the binding affinity • Monitored inventory of the lab weekly to ensure consumables and test articles were sufficient for experiments • Performed performance qualification of equipments and pipettes in the lab and submitted the findings in report
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MiRXES
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Singapore
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Research Officer/Lab Officer
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Jun 2018 - May 2023
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Singapore
• miRNA Profiling on clinical biofluid samples via qpcr• Manual data processing such as data cleaning and data extraction • Executed automated pipeline in MATLAB to process qpcr data such as data cleaning, data qc and data normalisation and troubleshooting of the data • Library construction for small RNA samples• Extracted small RNA on biofluid samples using Qiagen and Promega machines • RT-qPCR for experiments using Quantstudio and extracted data via commandline for analysis of CT values• Analysed small RNA library quality and size selection using Bioanalyser and E-gel • Sent samples for sequencing and performed data QC on the sequenced data and liased with the bioinformaticians on deeper data analysis • Performed QC experiments and comparison experiments using RT-qPCR methods for inventory items to ensure lot to lot variations are minimal• Managed inventory of the lab monthly to ensured smooth process during Audit • Database management of profiling qPCR data to compile clinical information and normalised data• Purchased inventory items, kits, reagents, assets using SAP system for the lab • Liased with various vendors and officers for smooth and timely deliveries • Performed logistics work such as shipping to various countries via various couriers for shipping of reagents and clinical samples • Worked with finance and management team closely to ensure purchases doesn’t exceed budget • Used AWS for uploading of sequencing data• Processed clinical blood samples from patients by centrifuging various components of the blood, checked for hemolysis state of the samples, recorded and stored the samples
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NovogeneAIT Genomics Singapore
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Singapore, Singapore
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Lab Officer
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Jun 2017 - May 2018
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Singapore, Singapore
• Extraction of genomic DNA from fresh blood samples using AbGenix machine• Whole genome sequencing library construction done by using various kits, ligation-based PCR methods and bead based purification methods. • Studied quantity and quality of samples using Qubit and Agarose Gel Electrophoresis sent by customers and reported findings to management to proceed with sequencing library preparation • Arranged for samples to be shipped to overseas countries in a team• Operated machines like Beckman and Hamilton robotic arms to aid in speeding up of the library construction processes when there are more samples • Analysed library quality and quantity using Labchip, Bioanalyser, qPCR methods respectively• Used unix system and basic python scripts to run commands using Cygwin and putty for data quality check and demultiplexing of the samples• Monitored lab inventory consumables monthly to ensure abundance of stock for experiments • Wrote Standard Operating Procedure documentation for demultiplexing and data quality checks
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Admin Assistant and Surveyor
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Apr 2016 - Jun 2017
• Organised meetups for the surveyors to meet survey participants and for applicants to attend interviews • Performed online form designs for online survey forms using simple html• Conducted survey via telephone and outdoor to different houses and areas to different participants• Wrote transcripts of audio and video group discussions held in the office
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CrimsonLogic Pte Ltd
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Singapore
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Project Administrator
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Aug 2014 - Mar 2016
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Singapore
• Performed in software testing for web application by designing and executing test scenarios and test cases based on current implementation and software requirement specifications to ensure accuracy and efficiency of the applications• Monitored the progress of the web application by compiling test results for reporting• Performed System Integration Testing (SIT), User Acceptance Testing (UAT), and coordinated with customers to ensure that customers are satisfied with the functionalities in the web applications• Investigated and confirmed bug fixes by doing regression and sanity testing on affected areas that enhanced the functionality of the web applications • Prepared and executed SQL statements and XML files in the database and SFTP respectively for execution of batch jobs that sped up the testing process by 50% • Presented findings to clients by explaining the functionalities based on their requirements• Executed automation scripts in Selenium for Sanity testing which sped up the testing by 90%
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Research Assistant
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May 2009 - Dec 2010
Gathering information on students learning experiences in Primary school and Secondary school.Collected and compiled the survey results for use in research.
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Education
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2012 - 2014The University of Queensland
Bachelor of Science (B.Sc.), Biological and Biomedical Sciences -
2008 - 2011Republic Polytechnic
Diploma, Biological and Biomedical Sciences
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