Experience

• 

  Forge Biologics

  • United States
  • Biotechnology Research
  • 300 - 400 Employee

  • Director of Downstream Process Development

    • 2023 - Present

  • Associate Director of Downstream Process Development

    • Jan 2022 - Jan 2023

• 

  Cytovance Biologics

  • United States
  • Biotechnology Research
  • 200 - 300 Employee

  • Senior Scientist

    • Jan 2021 - Mar 2022

    • Lead the team on Continuous Process Improvements for pDNA manufacturing for Gene therapy• Design and execute innovative process development and characterization activities for Phase III clients• Serves as an internal subject matter expert (SME) for Process Characterization studies for Phase III clients • Develop individual goals for team members and perform quarterly, mid-year and annual evaluations. • Troubleshooting production problems, deviation investigation and product impact assessment• Identify and recommend innovative technologies for evaluation and implementation of new processes

  • Scientist

    • Apr 2018 - Jan 2021

    • Independently lead and manage assigned projects coordinating closely with R&D team, MST and Manufacturing• Downstream process development for the purification of biological molecules intended for tox-studies and clinical trials• Prepared SOPs, Batch records, Tech transfer documents for Manufacturing • Applied understanding of regulatory expectations to process development strategies• Technical lead in the process development for pDNA manufacturing service for gene therapy products • Applies Design of Experiment and, QbD methodologies as needed • Developed and implemented new processes from concept through implementation

• 

  University of Oklahoma

  • United States
  • Higher Education
  • 700 & Above Employee

  • Research Assistant Professor

    • Mar 2013 - Apr 2018

    • Developed methods to understand kinetics of drug permeation through envelope of gram-negative pathogens • Multidrug efflux systems in Pseudomonas aeruginosa and Burkholderia species• Screening for novel Antibiotics and Multi-Drug Efflux pump inhibitors using newly developed hyper-porinated strains• Research mentoring of Post-Doctoral Scholars, Graduate and Undergraduate Students

  • Postdoctoral Research Associate

    • Jun 2008 - Mar 2013

  • Graduate research Assistant

    • Jan 2002 - Jun 2008

  • Graduate Teaching Assistant

    • Jan 2002 - Dec 2007

• 

  Anna University

  • Chennai, Tamil Nadu, India

  • Research Associate

    • Oct 1999 - Jun 2001
    • Chennai, Tamil Nadu, India

    • Assisted in the production of recombinant streptokinase from E. coli using fed batch and continuous culture conditions• Process development for the purification of Recombinant Streptokinase using AKTA/ UNICORN FPLC platform