Experience

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  VSY Biotechnology

  • İstanbul, Türkiye

  • Bioprocess Specialist

    • Oct 2020 - Present
    • İstanbul, Türkiye

    Leading a bacterial fermentation project teamSmall scale (erlen and 2L bioreactor) process optimization of upstream and downstream for the production of biopolymers using doe prensiblePlanning, conducting and interpreting the experimentManaging the project team, laboratory and project planDefining project needs, budget and timelineHandling of bacterial culture ( BSL-2) and generating productive bacterial cell and cell bank with mutation and selective selectionPurification of high molecular weight polymer in fermentation broth with using Ultrafiltration, Precipitation, Adsorption Scale-up (30L ) and process validation in upstream process.Planning pilot and production plant

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  Nobel Ilac A.S

  • İstanbul

  • Upstream Bioprocess Responsible

    • Oct 2018 - Oct 2020
    • İstanbul

    Handling of mammalian cell lines-different scale (Ambr 15, shake flask, 250 ml- 5L bioreactor) for process optimization.Data analysis and product development with desired quality,• Completing the qualifications of devices in the USP laboratory. Creating documents such as URS, HRLA, IQ, OQ and SOP.Coordinating of material and equipment supply. Procuring raw materials and equipment’s related to upstream and following up the installation procedures of the respective equipment,Performing R&D activities under the new product development directorate; Feasibility studies of new products,Involving in project writing and presentation for different institution grants(Tubitak, TUSEB) and creating project timeline, budget and business plans

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  Kocak İlac / Kocak Pharmaceuticals

  • Tekirdag, Turkey

  • Biotechnology Researcher

    • Jun 2017 - Sep 2018
    • Tekirdag, Turkey

    Conducting upstream and downstream studies of antigen molecule produced by recombinant yeast cell line,Preparating MCB and WCB of yeast cell lineFermentation of yeast in different scales bioreactor (2L and 30L)Cell lysis and purification steps; aerosil adsorption, precipitation and chromatography (AKTA avant and AKTA PILOT)Performing SDS-PAGE, ELISA and HPLC analysis and creating analysis methods for these,

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  Deva Holding A.Ş.

  • Intern

    • Aug 2015 - Aug 2015