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Bio

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Ashish Changediya is a seasoned researcher with expertise in pharmaceutical sciences, possessing a Master of Science degree from the University of Maryland, Baltimore (UMB) and a B. Tech from the Institute Of Chemical Technology. He has worked in various roles, including Research Intern at Sanofi, IBBR Institute for Bioscience and Biotechnology Research, and Johnson & Johnson, where he has gained experience in research, formulation, and design.

Experience

    • Senior Assosiate Scientist
      • Mar 2024 - Present

  • AstraZeneca
    • Gaithersburg, Maryland, United States
    • Antibody Research Co-op
      • Jun 2023 - Apr 2024
      • Gaithersburg, Maryland, United States

      • Performing deep screening for rapid discovery of high affinity antibodies via massively parallel Sequencing on high throughput DNA sequencing chip ( NGS flow cell) , in-vitro transcription, ribosomal display and affinity screening.• Hands-on experience on library preparation for Next Generation Sequencing. • Optimizing the sequencing workflow for antibody libraries and reducing experimental cost by Implementing Next Generation Sequencing (NGS) by Aviditi technology as a cost-effective alternative to Next Generation Sequencing by Synthesis.• Carrying out antibody lead optimization through antibody protein expression, biochemical assays, and correlation studies between antibodies and antigens.• Skilled in primer design for molecular biology applications, ensuring precise and efficient amplification of target sequences.• Developed ability to navigate genomics archives and databases hosted by UCSC, NCBI, ENSEMBL.• Independently recorded experiments performed in Electronic Lab Notebook and communicated results to the scientific team.• Followed cGMP, SOPs, safety regulations and good documentation practices.

    • Research Intern
      • Sep 2022 - May 2023
      • Rockville, Maryland, United States

      • Supported the development of an engineered chimeric endolysin targeting multiple host bacteria like group B Streptococci, Streptococcus pneumoniae, Streptococcus mutans, and Enterococcus faecalis.• Employed biochemical assays to determine optimal lytic condition and minimum inhibitory concentration.• Specialized skills in a Biosafety Level 2 (BSL-2) laboratory setting to ensure precision and adherence to safety protocols.

  • The Universities at Shady Grove
    • Rockville, Maryland, United States
    • Information Technology Help Desk Technician
      • Aug 2022 - Apr 2023
      • Rockville, Maryland, United States

      Assisted students as well as faculty with their computers and technology-related problems.Skills: IT Hardware Support · IT Service Management · Help Desk Support · IT Operations · Technical Support · Computer Hardware Troubleshooting

  • Sanofi
    • Goa, India
    • Research Intern
      • Jun 2022 - Aug 2022
      • Goa, India

      • Deformulation of components present and decoding process information of the innovator formulation using Raman Imaging and NIR Imaging. Distribution of each component were identified using chemometrics analysis.• Formulation process monitoring using NIR spectrophotometer and Multivariate Analysis.

  • Manzar ICT
    • Mumbai Area, India
    • Treasurer
      • May 2019 - Mar 2020
      • Mumbai Area, India

      Raised and managed a record-breaking sponsorship amount, INR 3 million and worked with 40 other team heads to organize events for 12,000 multilingual attendees.

  • Sanofi
    • India
    • Research Intern
      • Apr 2019 - Aug 2019
      • India

      • Worked on developing a more robust and rugged HPLC method for analysis, while working on Dapagliflozin and Metformin HCl Extended Release tablet.• Applied Differential Scanning Calorimetry to find glass transition temperature and XRPD to find crystalline phase of the material.• Used Solid State characterization tools in Reverse Engineering application

Education

  • 2022 - 2024
    University of Maryland, Baltimore (UMB)
    Master of Science - MS, Pharmaceutical Sciences
  • 2017 - 2021
    Institute Of Chemical Technology
    B. Tech, pharmacutical and chemical technology
  • 2013 - 2015
    Alphonsa school Yadrav
    10th graduation, 92%

Suggested Services

This profile is unclaimed. These are suggested service rates with 0% commision upon successful connection

Industry Focus. “Biotechnology and Pharmaceuticals”

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