Stephanie Martin

Research Scientist, Microbiology at Tezza
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Contact Information
us****@****om
(386) 825-5501
Location
Oakland, California, United States, US

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Experience

    • United States
    • Food and Beverage Services
    • 1 - 100 Employee
    • Research Scientist, Microbiology
      • Sep 2022 - Present

      Oakland, California, United States • Built selection and genomics pipeline for isolation and identification of microbes of interest • Screened and evaluated microbes for fermentation of plant-based milk into cheese • Assisted in cheese-making and on-boarding new technologies

    • Senior Producer
      • Jun 2016 - Present

      • Coordinate interviews and perform pre-interviews and briefing to prepare guests for recorded interviews • Identify and develop segments that translate new discoveries in tech and biotech for a mainstream audience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Research Associate II
      • Mar 2022 - Aug 2022

      • Developed tissue-based single-nucleus RNA-Seq methods • Performed complex but clean MOA studies for at least three programs in discovery and preclinical stages • Continued cell line development and cell-based assay development

    • Senior Research Associate
      • Nov 2019 - Mar 2022

      South San Francisco • Built and developed cell-based assays to screen chemical matter and investigate target biology for at least three indications in preclinical stages • Contributed to at least six programs by performing MOA studies and on-boarding new tools • Developed and validated over a dozen CRISPR cell lines and a handful of inducible systems - allelic series and tagged endogenous genetic targets • Trained and mentored peers in CRISPR basics and cell-line development • Supported AAV gene… Show more • Built and developed cell-based assays to screen chemical matter and investigate target biology for at least three indications in preclinical stages • Contributed to at least six programs by performing MOA studies and on-boarding new tools • Developed and validated over a dozen CRISPR cell lines and a handful of inducible systems - allelic series and tagged endogenous genetic targets • Trained and mentored peers in CRISPR basics and cell-line development • Supported AAV gene therapy program by developing in-house research grade AAV production methods, titering methods, and biodistribution assays

    • United States
    • Biotechnology
    • 1 - 100 Employee
    • Senior Research Associate
      • Apr 2019 - Aug 2019

      Mission Bay, San Francisco, CA • Optimized in vitro functional assay for CRISPR drug candidates in relevant cell lines • Performed functional assay for ex vivo FVIII expression in POC studies • Collaborated on transfer of NAb assay for IND-enabling studies

    • United States
    • Biotechnology Research
    • 100 - 200 Employee
    • Research Associate I-II
      • May 2017 - Mar 2019

      South San Francisco, California Preclinical and technology R&D. Molecular biology, tissue culture, and bioinformatics with some in vivo work. Technology project: High throughput functional screen assay • Established and optimized protocol (in vitro and in vivo): - 30,000+ member library cloning - transfection/transduction into cell lines of interest - nucleic acid extraction and sequencing library construction/validation - sequencing (hands-on with Illumina NextSeq) • NGS data… Show more Preclinical and technology R&D. Molecular biology, tissue culture, and bioinformatics with some in vivo work. Technology project: High throughput functional screen assay • Established and optimized protocol (in vitro and in vivo): - 30,000+ member library cloning - transfection/transduction into cell lines of interest - nucleic acid extraction and sequencing library construction/validation - sequencing (hands-on with Illumina NextSeq) • NGS data analysis to select high expressing promoters • Validated promoters in therapeutic vectors both by reporter gene assay and relevant functional assay Preclinical projects: Liver, CNS, and Multi-organ indications, in vitro/in vivo model development • Designed and assembled vector constructs to deliver potential drug candidates • Designed and executed in vitro/in vivo studies - relative gene expression - transcriptome (RNA-Seq) - protein presence, localization and function (Western blot, IHC, etc.) - disease biomarker assays • Collaborated with in vivo scientists and managed intern projects

    • Intern
      • Jun 2016 - May 2017

      South San Francisco, CA • Development, validation and implementation of high throughput assay for identification of promoters that drive high expression

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Student Assistant
      • Aug 2015 - May 2016

      School of Nursing and Health Professions • Assisted the Department of Integrated Health Supervisor in daily operations and data management

    • United States
    • Broadcast Media Production and Distribution
    • 1 - 100 Employee
    • Producer, Announcer
      • Jun 2014 - Jul 2015

      Abilene, Texas · 2014/2015 Most Valuable Producer Award · Managed station production and events calendar · Announced weather, underwriting, events calendar on-air; collaborated with on-air journalists · Formatted, imported, and queued all programs; edited and updated playlists; updated underwriting · Wrote and shared the local events calendar; maintained event calendar on the station website · Recorded automated promotions or other segments as needed

    • United States
    • Higher Education
    • 700 & Above Employee
    • Teaching Assistant
      • Aug 2014 - May 2015

      Department of Chemistry and Biochemistry Teaching Assistant with Dr. Sarah K. Lee, August 2014-Present · Prepared necessary solutions and equipment for biochemistry teaching lab · Poured columns; ran centrifuge, autoclave, thermal cycler, and incubator; prepared buffers and enzyme solutions; helped students during lab; graded quizzes and data analysis sheets

    • Undergraduate Student Researcher
      • Jun 2013 - May 2015

      Department of Chemistry and Biochemistry Abilene Christian University Student Research Institute - Abilene, Texas Undergraduate Research Intern with Dr. M. Cynthia Powell, Summer 2013 · Began project synthesizing and examining oxovanadium salophen complexes with novel microwave synthesis methods · Ran microwave reactions; collected, measured, and purified products; calculated yields; evaluated synthetic efficiency and made observations and collaborative decisions · Synthesized and identified four target complexes using… Show more Abilene Christian University Student Research Institute - Abilene, Texas Undergraduate Research Intern with Dr. M. Cynthia Powell, Summer 2013 · Began project synthesizing and examining oxovanadium salophen complexes with novel microwave synthesis methods · Ran microwave reactions; collected, measured, and purified products; calculated yields; evaluated synthetic efficiency and made observations and collaborative decisions · Synthesized and identified four target complexes using microwave synthesis, purification by recrystallization and infrared irradiation and NMR characterization Abilene Christian University Department of Chemistry and Biochemistry - Abilene, Texas Student Research Assistant with Dr. M. Cynthia Powell, August 2013­-May 2015 · Began osmium cluster project including: synthesizing and characterizing acetylene-substituted osmium clusters using microwave irradiation, column and thin-line chromatography, infrared radiation, and multiple methods of crystal growth · Continued investigation of different oxovanadium salophen complexes, including both traditional and microwave synthesis of ligands and substituted oxovanadium compounds · Collaborated closely with faculty and other research assistants Abstracts and Poster Presentations E.K. Fry, S.M. Martin, and M.C. Powell. New diosmium(I) compounds with cyclic acetylene ligands. Presented at the American Chemical Society National Meeting, 2014 and the Abilene Christian University Undergraduate Research Festival, 2014. S.M. Martin, E.K. Fry, and M.C. Powell. Microwave synthesis and characterization of oxovanadium salophen complexes. Presented at the American Chemical Society Southwest Regional Meeting, 2013 and the Abilene Christian University Undergraduate Research Festival, 2014

    • Student Worker
      • Jan 2012 - May 2015

      Adams Center for Teaching and Learning · Assisted the director in serving the faculty of the university though operations, supporting the Center's mission to foster continuing education for faculty

Education

  • University of San Francisco
    Professional Science Masters, Biotechnology
    2015 - 2017
  • Abilene Christian University
    Bachelor of Arts (B.A.), Biochemistry
    2011 - 2014
  • Cheyenne East High School
    International Baccalaureate Certificate, 4.0 GPA
    2007 - 2011

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