Dan Xia
Principal Scientist, Preclinical Translational Sciences at Denali Therapeutics- Claim this Profile
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Experience
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Denali Therapeutics
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United States
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Biotechnology Research
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200 - 300 Employee
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Principal Scientist, Preclinical Translational Sciences
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Aug 2023 - Present
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Senior Scientist, Translational Science
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Sep 2020 - Aug 2023
South San Francisco, California, United States
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In Vivo Scientist, Preclinical Translational Biology
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Aug 2017 - Aug 2020
South San Francisco, California, United States
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Harvard Medical School
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United States
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Higher Education
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700 & Above Employee
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Instructor
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Jan 2016 - Aug 2017
Greater Boston Area I have been studying the pathological functions of C-terminal fragments of amyloid precursor protein (APP CTFs) in Alzheimer’s disease and I'm also developing high-throughput screening assay for compounds to enhance γ-secretase activities.
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Postdoctoral Research Fellow
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Oct 2008 - Dec 2015
I studied the pathogenic mechanisms of familial Alzheimer’s disease in Presenilin knockin mouse models and cell culture system and I also investigated the levels of Presenilin in the progress of frontotemporal dementia and aging.
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Brigham and Women's Hospital
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United States
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Hospitals and Health Care
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700 & Above Employee
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Assistant Scientist
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Jan 2016 - Aug 2017
Greater Boston Area
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Peking Union Medical College
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China
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Higher Education
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1 - 100 Employee
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Graduate Student
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Sep 2002 - Sep 2008
Beijing City, China I identified and characterized acute myeloid leukemia linked bro-1 gene in C.elegans and I also isolated the novel genes that control the timing of stem cell division.
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Education
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Peking Union Medical College
Ph.D., Biochemistry and Molecular Biology -
Wuhan University
Bachelor's degree, Microbiology