Overview

Nanomedicines are nano-scale vehicles that deliver drugs inside the human body. They allow drugs to be carried and applied to diseased cells while avoiding secondary effects on healthy cells. This technology can improve a patient’s quality of life by reducing treatment side effects and at the same time it facilitates increases in dose amount, resulting in more effective therapies. After almost 40 years of intense research in nanomedicines, only a few dozen products worldwide have reached patients. The main obstacle is their dependence to the manufacturing process, while being complex systems. Traditional technologies manufacture nanomedicines in turbulent flows, with uncontrolled synthesis and high consumption of reagents. These methods are far from optimal for the pharmaceutical industry due to the batch-to-batch variations, the synthesis' long length of time, high waste of reagents, and difficulties both in scalability and optimization. PLAMIC uses microfluidics to develop and produce nanomedicines, overcoming the important limitations of traditional methods. Our technology uses microchannels that are designed small enough to obtain a low Reynolds number for fluids within them. This results in a laminar regime that allows for a precise control of fluid movement in a chip that fits in the palm of the hand. With the expertise the PLAMIC team has with both microfluidics and nanomedicines, we are able to obtain chips for unique nanomedicine formulations. PLAMIC has been successful getting reproducible nanomedicines with pharmaceutical quality, and at the same time, accessibility to scale its production process to supply industrial demands. We believe that we will make a historical breakthrough in the pharmaceutical industry’s efficiency and capacity at developing and producing new products. We are here to obtain more and better treatments for patients.