Ziv Roth
Research Associate at Faculty of Dentistry at the University of Toronto- Claim this Profile
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Bio
Experience
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Faculty of Dentistry | University of Toronto
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Canada
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Higher Education
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1 - 100 Employee
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Research Associate
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Nov 2020 - Present
I study macrophage-fibroblast interactions in the context of lung fibrosis. I study macrophage-fibroblast interactions in the context of lung fibrosis.
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The Hospital for Sick Children
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Canada
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Hospitals and Health Care
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700 & Above Employee
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Postdoctoral Fellow
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Jul 2016 - Nov 2020
My research focused on macrophage polarization using human monocyte derived macrophages. I studied the effect of GM-CSF on macrophage morphology and function and how macrophages express and secrete Apolipoprotein E (ApoE). My research focused on macrophage polarization using human monocyte derived macrophages. I studied the effect of GM-CSF on macrophage morphology and function and how macrophages express and secrete Apolipoprotein E (ApoE).
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Ben-Gurion University of the Negev
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Israel
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Higher Education
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700 & Above Employee
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Apr 2013 - Jun 2016
I studied a unique mycobacterial protein degradation system. My project focused on inhibiting a key enzymatic reaction, and by that develop a novel anti-tuberculosis therapeutics. To do so, I preformed a High Throughput Screening of small molecules and found several potent inhibitors.
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Oct 2008 - Mar 2013
During my PhD I studied protein glycosylation and how it affects the ligand-receptor interaction of the yolk protein precursor and its lipoprotein-receptor on the developing oocyte. To do so I used molecular, biochemical and proteomics methods. One of the key findings was that the ligand-receptor interaction site, is evolutionary conserved in all egg laying organisms and even mammals.
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Education
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Ben-Gurion University of the Negev
Doctor of Philosophy (PhD), Biochemistry and Molecular Biology -
Ben-Gurion University of the Negev
M.Sc, Biochemistry