Experience

Suzhou Zelgen Biopharmaceutical Co., Ltd.

• China
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Director of analytic development

  • May 2021 - Present

  1) managed the structural characterization of 5 BsAbs(IND stage), and recombinant human thyroid hormone (rhTSH, BLA stage), and wrote the corresponding chapters in the filing dossiers. 2) Assessed and optimized various stability-indicating methods (RP-HPLC, SEC-HPLC, IEX-HPLC, and CE-SDS) 3) Managed the analytical team to support process development and antibody discovery 4)Identified and characterized various structural variants and impurities in process development 1) managed the structural characterization of 5 BsAbs(IND stage), and recombinant human thyroid hormone (rhTSH, BLA stage), and wrote the corresponding chapters in the filing dossiers. 2) Assessed and optimized various stability-indicating methods (RP-HPLC, SEC-HPLC, IEX-HPLC, and CE-SDS) 3) Managed the analytical team to support process development and antibody discovery 4)Identified and characterized various structural variants and impurities in process development



GenScript

• United States
• Biotechnology Research
• 400 - 500 Employee

• Senior Manager of Protein Analytics

  • Mar 2019 - May 2021

  1) Built the LC-MS capacity of analyzing> 1000 samples/month 2) Managed other analytics for proteins (SEC-HPLC, Endotoxin, Native-mass and SEC-MALS, SDS-PAGE and CE-SDS, Concentration, Cedex Bio-analyzer). 1) Built the LC-MS capacity of analyzing> 1000 samples/month 2) Managed other analytics for proteins (SEC-HPLC, Endotoxin, Native-mass and SEC-MALS, SDS-PAGE and CE-SDS, Concentration, Cedex Bio-analyzer).



WuXi Biologics

• China
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Scientist II

  • Sep 2016 - Feb 2019

  1) Managed Protein Analytics (LC-MS, SEC-HPLC, CE-SDS/SDS-PAGE, endotoxin) 2) Single-handedly manufactured >2 mg of nucleosomes with H3K36me2 for Alpha-screen 3) Single-handedly developed, validated, and deployed an RP-HPLC method for measuring titer of antibody fragments from cultures of CHO Cells 4) Spear-headed the refolding of a series of MHCI complex for discovery of cancer neo-antigen 1) Managed Protein Analytics (LC-MS, SEC-HPLC, CE-SDS/SDS-PAGE, endotoxin) 2) Single-handedly manufactured >2 mg of nucleosomes with H3K36me2 for Alpha-screen 3) Single-handedly developed, validated, and deployed an RP-HPLC method for measuring titer of antibody fragments from cultures of CHO Cells 4) Spear-headed the refolding of a series of MHCI complex for discovery of cancer neo-antigen



Northwestern University

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Researcher in Biophysics

  • Oct 2014 - Aug 2016

  1) Manufactured nucleosomes bearing specific acetyl lysines for probing the SAR (structure-and-activity relationship) of histone-deacetylation complexes (HDACs) 2) Solution NMR studies of nuclear receptors 1) Manufactured nucleosomes bearing specific acetyl lysines for probing the SAR (structure-and-activity relationship) of histone-deacetylation complexes (HDACs) 2) Solution NMR studies of nuclear receptors