Zixuan Shao, Ph.D.
Research Scientist at Allegro Ophthalmics, LLC- Claim this Profile
Click to upgrade to our gold package
for the full feature experience.
Topline Score
Bio
Experience
-
Allegro Ophthalmics, LLC
-
United States
-
Pharmaceutical Manufacturing
-
1 - 100 Employee
-
Research Scientist
-
Jan 2019 - Present
• Develop and maintain NGS analysis pipelines (Bash and R) to facilitate pharmacodynamics and toxicology studies of ophthalmic drug candidates. • Effectively manage preclinical research programs across six academic labs and four research institutes that produced three scholarly journal publications. • Coordinate with research teams to plan RNA-seq and molecular experiments, interpret data, and generate research reports. • Forge new commercial partnerships as a member of the business development team. • Collaborate with the clinical team to expand therapeutic pipeline into new indications.
-
-
-
Audentes Therapeutics
-
Biotechnology Research
-
Bioinformatics Consultant
-
Dec 2017 - Jan 2019
• Created cloud and local pipelines containing established bioinformatics tools to analyze NGS data (genomics & RNA-seq). • Worked with R&D groups to generate quantitative information on the performance of gene therapy products. • Created cloud and local pipelines containing established bioinformatics tools to analyze NGS data (genomics & RNA-seq). • Worked with R&D groups to generate quantitative information on the performance of gene therapy products.
-
-
-
Caltech
-
United States
-
IT Services and IT Consulting
-
1 - 100 Employee
-
Doctoral Student
-
Jun 2013 - Jan 2019
• Combined RNA-seq and shotgun proteomics (LC/MSMS) to study ocular diseases and the biological response induced by therapeutics. • Designed and developed analytical software packages (ERSSA at Bioconductor) and workflows in Python, R, and Bash for RNA-seq data analysis. • Provided monthly research presentations and annual progress reports to pharmaceutical company collaborators. • Combined RNA-seq and shotgun proteomics (LC/MSMS) to study ocular diseases and the biological response induced by therapeutics. • Designed and developed analytical software packages (ERSSA at Bioconductor) and workflows in Python, R, and Bash for RNA-seq data analysis. • Provided monthly research presentations and annual progress reports to pharmaceutical company collaborators.
-
-
-
-
Business Development Consultant
-
Dec 2016 - Nov 2017
• Generated primary industry due diligence through review of scientific literature and public resources. • Maintained disease/therapeutic databases for competitive landscape and product opportunity analysis. • Generated primary industry due diligence through review of scientific literature and public resources. • Maintained disease/therapeutic databases for competitive landscape and product opportunity analysis.
-
-
-
Roche
-
Switzerland
-
Biotechnology Research
-
700 & Above Employee
-
Bioinformatics Intern
-
Jun 2017 - Sep 2017
• Studied public-sourced human genetic variant databases to identify reliable and accurate datasets for variant library generation. • Conducted performance analysis of genomics NGS software for potential utility in internal analytical pipelines. • Studied public-sourced human genetic variant databases to identify reliable and accurate datasets for variant library generation. • Conducted performance analysis of genomics NGS software for potential utility in internal analytical pipelines.
-
-
-
-
Summer Intern
-
Jun 2011 - Sep 2011
• Performed genetic engineering of microbial strains resulting in successful improvement of production performance. • Performed genetic engineering of microbial strains resulting in successful improvement of production performance.
-
-
Education
-
Caltech
Ph.D., Bioengineering -
University of California, San Diego
B.S., Biochemistry, Cell Biology. Minor in Economics