Zixuan Shao, Ph.D.

Research Scientist at Allegro Ophthalmics, LLC
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Contact Information
us****@****om
(386) 825-5501
Location
US

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Experience

    • United States
    • Pharmaceutical Manufacturing
    • 1 - 100 Employee
    • Research Scientist
      • Jan 2019 - Present

      • Develop and maintain NGS analysis pipelines (Bash and R) to facilitate pharmacodynamics and toxicology studies of ophthalmic drug candidates. • Effectively manage preclinical research programs across six academic labs and four research institutes that produced three scholarly journal publications. • Coordinate with research teams to plan RNA-seq and molecular experiments, interpret data, and generate research reports. • Forge new commercial partnerships as a member of the business development team. • Collaborate with the clinical team to expand therapeutic pipeline into new indications.

    • Biotechnology Research
    • Bioinformatics Consultant
      • Dec 2017 - Jan 2019

      • Created cloud and local pipelines containing established bioinformatics tools to analyze NGS data (genomics & RNA-seq). • Worked with R&D groups to generate quantitative information on the performance of gene therapy products. • Created cloud and local pipelines containing established bioinformatics tools to analyze NGS data (genomics & RNA-seq). • Worked with R&D groups to generate quantitative information on the performance of gene therapy products.

    • United States
    • IT Services and IT Consulting
    • 1 - 100 Employee
    • Doctoral Student
      • Jun 2013 - Jan 2019

      • Combined RNA-seq and shotgun proteomics (LC/MSMS) to study ocular diseases and the biological response induced by therapeutics. • Designed and developed analytical software packages (ERSSA at Bioconductor) and workflows in Python, R, and Bash for RNA-seq data analysis. • Provided monthly research presentations and annual progress reports to pharmaceutical company collaborators. • Combined RNA-seq and shotgun proteomics (LC/MSMS) to study ocular diseases and the biological response induced by therapeutics. • Designed and developed analytical software packages (ERSSA at Bioconductor) and workflows in Python, R, and Bash for RNA-seq data analysis. • Provided monthly research presentations and annual progress reports to pharmaceutical company collaborators.

    • Business Development Consultant
      • Dec 2016 - Nov 2017

      • Generated primary industry due diligence through review of scientific literature and public resources. • Maintained disease/therapeutic databases for competitive landscape and product opportunity analysis. • Generated primary industry due diligence through review of scientific literature and public resources. • Maintained disease/therapeutic databases for competitive landscape and product opportunity analysis.

    • Switzerland
    • Biotechnology Research
    • 700 & Above Employee
    • Bioinformatics Intern
      • Jun 2017 - Sep 2017

      • Studied public-sourced human genetic variant databases to identify reliable and accurate datasets for variant library generation. • Conducted performance analysis of genomics NGS software for potential utility in internal analytical pipelines. • Studied public-sourced human genetic variant databases to identify reliable and accurate datasets for variant library generation. • Conducted performance analysis of genomics NGS software for potential utility in internal analytical pipelines.

    • Summer Intern
      • Jun 2011 - Sep 2011

      • Performed genetic engineering of microbial strains resulting in successful improvement of production performance. • Performed genetic engineering of microbial strains resulting in successful improvement of production performance.

Education

  • Caltech
    Ph.D., Bioengineering
    2013 - 2019
  • University of California, San Diego
    B.S., Biochemistry, Cell Biology. Minor in Economics
    2008 - 2012

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