Zach Smith

Graduate Student at Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo
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Contact Information
us****@****om
(386) 825-5501
Location
Plymouth, Michigan, United States, US

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Experience

    • Graduate Student
      • Oct 2021 - Present

      Thesis research on the role of iron metabolism in astrocytes during neuroinflammation. Thesis research on the role of iron metabolism in astrocytes during neuroinflammation.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Technician II
      • Jan 2019 - Jun 2021

      Research tech in neurology lab studying alpha-synuclein aggregation and Parkinson's Disease. Research tech in neurology lab studying alpha-synuclein aggregation and Parkinson's Disease.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Research Assistant
      • May 2016 - May 2018

      Part time research in a structural biology and x-ray crystallography lab. Expressed recombinant proteins related to the initiation of autophagy in E. Coli and purified using affinity chromatography, anion exchange, and size exclusion. Purified proteins were screened with different conditions and hits were further optimized to grow crystals sufficient for x-ray analysis. Research was done under the primary investigator, Dr. Xiangshu Jin. Part time research in a structural biology and x-ray crystallography lab. Expressed recombinant proteins related to the initiation of autophagy in E. Coli and purified using affinity chromatography, anion exchange, and size exclusion. Purified proteins were screened with different conditions and hits were further optimized to grow crystals sufficient for x-ray analysis. Research was done under the primary investigator, Dr. Xiangshu Jin.

    • Summer Research Fellow
      • May 2017 - Aug 2017

      Full time research in a protein quality control lab. Cultured primate cells with tagged proteins and biochemical markers to assess the interaction between a modified E3 ligase and HSP70 and determine if the E3 ligase function was retained. Research was done under the primary investigator, Dr. Jonathan Schisler. Full time research in a protein quality control lab. Cultured primate cells with tagged proteins and biochemical markers to assess the interaction between a modified E3 ligase and HSP70 and determine if the E3 ligase function was retained. Research was done under the primary investigator, Dr. Jonathan Schisler.

    • Germany
    • Chemical Manufacturing
    • 700 & Above Employee
    • TPU Development Summer Hire
      • May 2015 - Aug 2015

      Worked with TPU Development Team to develop and test different plastics that had potential in market. Hand mixed different polymers, ground down polymer slabs, compounded polymer to alter properties, and tested final product. All work with and around heavy machinery done in compliance with OSHA guidelines. Worked with TPU Development Team to develop and test different plastics that had potential in market. Hand mixed different polymers, ground down polymer slabs, compounded polymer to alter properties, and tested final product. All work with and around heavy machinery done in compliance with OSHA guidelines.

Education

  • Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo
    Master of Science - MS, Pharmacology and Toxicology
    2021 - 2023
  • Michigan State University
    Bachelor’s Degree, Biochemistry and Molecular Biology
    2014 - 2018

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