Zach Hanf
Product Scientist - Bioinformatics at Daicel Arbor Biosciences- Claim this Profile
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Bio
Experience
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Daicel Arbor Biosciences
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United States
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Biotechnology Research
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1 - 100 Employee
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Product Scientist - Bioinformatics
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May 2021 - Present
Ann Arbor, Michigan, United States • Created and built from scratch the modular cloud-based pipeline Arbor Biosciences uses for their bioinformatics product offering. Written in python, it runs full end-to-end custom cloud bioinformatic pipelines that process customer sequencing data from our in-house target enrichment experiments. • Designed and built the customer facing web-based data delivery platform for bioinformatics as a service. Written in FLASK it allows for the download of relevant files, automatically generates… Show more • Created and built from scratch the modular cloud-based pipeline Arbor Biosciences uses for their bioinformatics product offering. Written in python, it runs full end-to-end custom cloud bioinformatic pipelines that process customer sequencing data from our in-house target enrichment experiments. • Designed and built the customer facing web-based data delivery platform for bioinformatics as a service. Written in FLASK it allows for the download of relevant files, automatically generates PDF reports, and displays relevant graphs, tables, and statistics summarizing client capture experiments.
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Associate Product Scientist - NGS
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Aug 2019 - May 2021
Ann Arbor, Michigan, United States • Create and implement novel algorithms and software for the design, analysis, quality control, and visualization of RNA based hybridization probes for use in client’s targeted capture experiments. • Lead R&D efforts to create and deploy machine learning techniques (Linear Regression, KNN, Random Forest, CNN) to improve pipelines involving bait design, filtering, and synthesis. • Created multiple internal web applications (using flask, SQL, and JavaScript) for use by multiple… Show more • Create and implement novel algorithms and software for the design, analysis, quality control, and visualization of RNA based hybridization probes for use in client’s targeted capture experiments. • Lead R&D efforts to create and deploy machine learning techniques (Linear Regression, KNN, Random Forest, CNN) to improve pipelines involving bait design, filtering, and synthesis. • Created multiple internal web applications (using flask, SQL, and JavaScript) for use by multiple departments in the company, while simultaneously automating many manual processes.
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The Ohio State University
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United States
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Higher Education
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700 & Above Employee
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Graduate Teaching Assistant
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Aug 2017 - Nov 2022
Columbus, Ohio Area Roles: - Coordinates and facilitates learning for Undergraduates in a laboratory setting. - Effectively communicates and disseminates information to a broad diversity of students. - Designs and executes recitation activities to enhance/supplement student's lecture materials. - Brainstorming, organizing, and following through with Student Learning-Service Experiences. Classes Taught: - Introductory Biology 1113 (Genetics) - Introductory Biology 1114 (Evolutionary… Show more Roles: - Coordinates and facilitates learning for Undergraduates in a laboratory setting. - Effectively communicates and disseminates information to a broad diversity of students. - Designs and executes recitation activities to enhance/supplement student's lecture materials. - Brainstorming, organizing, and following through with Student Learning-Service Experiences. Classes Taught: - Introductory Biology 1113 (Genetics) - Introductory Biology 1114 (Evolutionary Principles) - Human Anatomy and Physiology.
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Graduate Researcher
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Aug 2017 - Nov 2022
Columbus, Ohio Area - Assembled deNovo Genome, Transcriptome, and Proteome for North-American Short-Tailed Shrew (Blarina brevicauda) in order to investigate composition of their venom. - Employed multiple bioinformatic based pipelines in order to filter genomic and transcriptomic data in search of novel venom genes. -Isolated DNA/RNA and prepared sequencing libraries for multiple Next-Generation Sequencing (NGS) technologies; including Illumina short-read and Nanopore Minion. … Show more - Assembled deNovo Genome, Transcriptome, and Proteome for North-American Short-Tailed Shrew (Blarina brevicauda) in order to investigate composition of their venom. - Employed multiple bioinformatic based pipelines in order to filter genomic and transcriptomic data in search of novel venom genes. -Isolated DNA/RNA and prepared sequencing libraries for multiple Next-Generation Sequencing (NGS) technologies; including Illumina short-read and Nanopore Minion. short-read and Minion - Gained proficiency in Unix based systems and multiple bioinformatic programs. - Sought and applied for funding opportunities through various funding organizations.
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Ohio State University Comprehensive Cancer Center-James Cancer Hospital & Solove Research Institute
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United States
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Hospitals and Health Care
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700 & Above Employee
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Clinical Trial Intern
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Jul 2016 - Mar 2017
Columbus, Ohio Area - Coordinated and prepared sample collection for over 250 patients on a multitude of different Cancer Clinical Trials. - Ensured patient progression through multiple stages of each trial. - Collected and processed human blood, saliva, and urine samples for analysis and assessment of regimen efficacy.
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The Ohio State University Wexner Medical Center
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United States
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Hospitals and Health Care
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700 & Above Employee
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Family Support Intern-Surgical Intensive Care Unit
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Sep 2014 - Nov 2015
Columbus, Ohio Area - Worked as a liaison between patient's families and the medical staff. - Relayed medical information, coordinated visitation, and oriented family members upon first arrival in the Surgical Intensive Care Unit.
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Special Projects Intern
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May 2015 - Aug 2015
Zanesville Ohio - Sought creative solutions to issues impeding the dispersal of parts to retail stores. - Presented project progress in meetings. - Expedited processes Nationwide.
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Education
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The Ohio State University
Master's degree, Evolutionary Biology -
The Ohio State University
Biological Sciences, Molecular Genetics