Experience

Vicinitas Therapeutics

• United States
• Biotechnology Research
• 1 - 100 Employee

• Associate Director

  • Nov 2022 - Present

  Discovery Biology Discovery Biology



Bristol Myers Squibb

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Principal Scientist

  • Nov 2022 - Nov 2022

  Small Molecule Drug Discovery, Protein Homeostasis Center of Excellence, Molecular and Cell BiologyStudies on molecular glue, including 'target centric glue' and CELMoD. Saturation mutagenesis of canonical and non-canonical degrons of CELMoD targets. TCG and CELMoD SAR studies using NanoBRET, AlphaScreen and degradation, ligand competition assays.Contribute to and collaborate on photo-affinity labeling and proximity labeling based microenvironment mapping platforms for funcitonal interactome analysis. Show less

• Senior Scientist, Small Molecule Drug Discovery, Protein Homeostasis

  • Sep 2021 - Nov 2022

  Research and Early Development, Small Molecule Drug Discovery, Protein Homeostasis, Cell BiologyDevelopment and utility of chemogenetic inducible proximity POC approach for targeted protein degradation or stabilization with novel ubiquitination or non-ubiquitination machineries.Contribute to MOA studies of a clinical-stage protein degrader against a T cell checkpoint I/O target. Development of high-throughput CETSA platform for intracellular target engagement validation and screening. Including NanoBiT-CETSA and Alpha-CETSA. Show less

• Scientist, Cardiovascular Disease Biology, Molecular Biology

  • Nov 2020 - Sep 2021

  • Connecting and communicating with multi-disciplinary groups including Disease Biology, Molecular Biology, Small Molecule Drug Discovery and LDO, to collaborate on development of a crucial tissue selective new technology and drug development platform.• Inventing fluorescence and bioluminescence genetic reporters and functional assays for high-throughput drug screening and practice these assays in cell-based complex gene circuits and cellular functions.



MyoKardia

• United States
• Biotechnology Research
• 1 - 100 Employee

• Scientist I, Molecular Biology

  • Nov 2020 - Sep 2021

  Application of genetic engineering in research and development of therapeutic modalities for cardiovascular diseases. Application of genetic engineering in research and development of therapeutic modalities for cardiovascular diseases.



UT Southwestern Medical Center

• United States
• Hospitals and Health Care
• 700 & Above Employee

• Instructor

  • Sep 2020 - Nov 2020

  Working on new interdisciplinary projects of circadian rhythms, based on several technology platforms, especially advanced in vivo imaging approaches, CRISPRa and CRISPRi delivered gene regulation and ES cell derived organoid culture. The fields are related to tumorigenesis, neurology and metabolism.

• Research Scientist

  • Aug 2014 - Aug 2020

• Postdoctoral Researcher

  • Aug 2009 - Aug 2014