Yongchan Lee
Research Scientist at Elucida Oncology, Inc.- Claim this Profile
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Bio
Experience
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Elucida Oncology, Inc.
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United States
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Biotechnology Research
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1 - 100 Employee
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Research Scientist
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Mar 2022 - Present
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FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, THE
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United States
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Hospitals and Health Care
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1 - 100 Employee
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Research Scientist
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Aug 2020 - Mar 2022
• Extracellular CIRP induces macrophage extracellular trap formation via gasdermin D activation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732379/ • Neutrophil trogocytosis during their trans-endothelial migration: role of extracellular CIRP https://link.springer.com/article/10.1186/s10020-022-00515-3 • Extracellular CIRP induces macrophage extracellular trap formation via gasdermin D activation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732379/ • Neutrophil trogocytosis during their trans-endothelial migration: role of extracellular CIRP https://link.springer.com/article/10.1186/s10020-022-00515-3
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Memorial Sloan Kettering Cancer Center
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United States
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Hospitals and Health Care
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700 & Above Employee
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Research Associate
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Aug 2013 - Jul 2020
Entosis in Caenorhabditis elegans • Developed timelapse imaging method to study linker cell engulfment in male Caenorhabditis elegans • Analyzed the entotic engulfment of the linker cell • Entotic cell death in cancer cells Entosis in Caenorhabditis elegans • Developed timelapse imaging method to study linker cell engulfment in male Caenorhabditis elegans • Analyzed the entotic engulfment of the linker cell • Entotic cell death in cancer cells
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Cornell University
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United States
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Higher Education
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700 & Above Employee
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Postdoctoral Associate
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Jul 2011 - Jun 2013
Allergic asthma and immune cell signaling • Determined the role of Drebrin in basophil and mast cell function downstream of the high affinity FcεR and role of Drebrin in allergic responses. • Generated analog-sensitive kinase allele of IL-2 inducible T-cell kinase and the generation of transgenic mouse that has the ITKas Allergic asthma and immune cell signaling • Determined the role of Drebrin in basophil and mast cell function downstream of the high affinity FcεR and role of Drebrin in allergic responses. • Generated analog-sensitive kinase allele of IL-2 inducible T-cell kinase and the generation of transgenic mouse that has the ITKas
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Korea University
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South Korea
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Higher Education
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700 & Above Employee
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Postdoctoral Associate
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Oct 2010 - Jun 2011
Development of high efficiency antibody based assay methods • Increased the sensitivity of the antibody based assaysoptimization and signal amplification of ELISA, Western Blot, Influenza A/B rapid test kit (US patent pending; US20130323717A1): Development of high efficiency antibody based assay methods • Increased the sensitivity of the antibody based assaysoptimization and signal amplification of ELISA, Western Blot, Influenza A/B rapid test kit (US patent pending; US20130323717A1):
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Korea University
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South Korea
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Higher Education
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700 & Above Employee
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Graduate Student
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Mar 2001 - Aug 2010
Development of recombinant antibody-toxin fusion proteins • Increased yield of cancer-specific divalent Fab-toxin fusion protein utilizing repeats of the fab binding domain of protein G Researching the anticancer effects of curcumin derivatives • Analyzed the anticancer activity of curcumin derivatives • Analyzed the enhancement of the activity by ionizing radiation in human cancer cells. Development of recombinant antibody-toxin fusion proteins • Increased yield of cancer-specific divalent Fab-toxin fusion protein utilizing repeats of the fab binding domain of protein G Researching the anticancer effects of curcumin derivatives • Analyzed the anticancer activity of curcumin derivatives • Analyzed the enhancement of the activity by ionizing radiation in human cancer cells.
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Education
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Korea University
Doctor of Philosophy - PhD, Biochemistry -
Korea University
Master of Science - MS, Biochemistry -
Soonchunhyang University
Bachelor's degree, Biology, General