Yongchan Lee

Research Scientist at Elucida Oncology, Inc.
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Contact Information
us****@****om
(386) 825-5501
Location
Princeton Junction, New Jersey, United States, JE

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Scientist
      • Mar 2022 - Present

    • United States
    • Hospitals and Health Care
    • 1 - 100 Employee
    • Research Scientist
      • Aug 2020 - Mar 2022

      • Extracellular CIRP induces macrophage extracellular trap formation via gasdermin D activation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732379/ • Neutrophil trogocytosis during their trans-endothelial migration: role of extracellular CIRP https://link.springer.com/article/10.1186/s10020-022-00515-3 • Extracellular CIRP induces macrophage extracellular trap formation via gasdermin D activation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732379/ • Neutrophil trogocytosis during their trans-endothelial migration: role of extracellular CIRP https://link.springer.com/article/10.1186/s10020-022-00515-3

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Associate
      • Aug 2013 - Jul 2020

      Entosis in Caenorhabditis elegans • Developed timelapse imaging method to study linker cell engulfment in male Caenorhabditis elegans • Analyzed the entotic engulfment of the linker cell • Entotic cell death in cancer cells Entosis in Caenorhabditis elegans • Developed timelapse imaging method to study linker cell engulfment in male Caenorhabditis elegans • Analyzed the entotic engulfment of the linker cell • Entotic cell death in cancer cells

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Associate
      • Jul 2011 - Jun 2013

      Allergic asthma and immune cell signaling • Determined the role of Drebrin in basophil and mast cell function downstream of the high affinity FcεR and role of Drebrin in allergic responses. • Generated analog-sensitive kinase allele of IL-2 inducible T-cell kinase and the generation of transgenic mouse that has the ITKas Allergic asthma and immune cell signaling • Determined the role of Drebrin in basophil and mast cell function downstream of the high affinity FcεR and role of Drebrin in allergic responses. • Generated analog-sensitive kinase allele of IL-2 inducible T-cell kinase and the generation of transgenic mouse that has the ITKas

    • South Korea
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Associate
      • Oct 2010 - Jun 2011

      Development of high efficiency antibody based assay methods • Increased the sensitivity of the antibody based assaysoptimization and signal amplification of ELISA, Western Blot, Influenza A/B rapid test kit (US patent pending; US20130323717A1): Development of high efficiency antibody based assay methods • Increased the sensitivity of the antibody based assaysoptimization and signal amplification of ELISA, Western Blot, Influenza A/B rapid test kit (US patent pending; US20130323717A1):

    • South Korea
    • Higher Education
    • 700 & Above Employee
    • Graduate Student
      • Mar 2001 - Aug 2010

      Development of recombinant antibody-toxin fusion proteins • Increased yield of cancer-specific divalent Fab-toxin fusion protein utilizing repeats of the fab binding domain of protein G Researching the anticancer effects of curcumin derivatives • Analyzed the anticancer activity of curcumin derivatives • Analyzed the enhancement of the activity by ionizing radiation in human cancer cells. Development of recombinant antibody-toxin fusion proteins • Increased yield of cancer-specific divalent Fab-toxin fusion protein utilizing repeats of the fab binding domain of protein G Researching the anticancer effects of curcumin derivatives • Analyzed the anticancer activity of curcumin derivatives • Analyzed the enhancement of the activity by ionizing radiation in human cancer cells.

Education

  • Korea University
    Doctor of Philosophy - PhD, Biochemistry
    2001 - 2010
  • Korea University
    Master of Science - MS, Biochemistry
    1999 - 2001
  • Soonchunhyang University
    Bachelor's degree, Biology, General
    1992 - 1999

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