Experience

Janssen Vaccines & Prevention B.V.

• Netherlands
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Scientist

  • Sep 2018 - Present



Teva Pharmaceuticals

• Israel
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Analytical Scientist

  • Nov 2017 - Aug 2018

  Analytical Scientist for injectable complex  New therapeutic entity polymeric microsphere project at the late stage of development To develop analytical methods for quality control of scale-up, pilot and manufacturing batches - Characterization of core manufacturing equipment - Accelerated in vitro release method for formulation comparison - Analytical methods for in process control - Plans for stability study under storage, accelerated and stressed conditions - Recovery study for non-GLP study  Generic polymeric microsphere project at the early stage of development To develop in-depth characterization for reverse engineering and formulation development, and provide scientific advice for formulation optimization - In-depth characterization plan for reference listed drug and generic products - Preformulation study for API, including solubility, API particle size distribution, thermal properties, crystallinity, etc. - Extraction and characterization of polymer in microspheres, including end group analysis, polymer structure, molecular weight determination, etc. - Characterization of microspheres, including API distribution, particle size distribution, morphology, porosity/specific surface area/density, in vitro release, degradation, etc. - Supervision and guidance of technicians to perform experiments. Show less



Utrecht University

• Netherlands
• Higher Education
• 700 & Above Employee

• PHD Candidate

  • Sep 2012 - Jul 2017

  Design and evaluation of polymeric nanogels with tailorable degradation and controlled drug release  Design, synthesis and characterization of functional monomers and polymers.  Design, development and characterization of (active targeted) biodegradable (DOX-loaded) nanogel delivery systems, including nanogels with tailorable degradation behavior, and DOX-loaded nanogels with pH/ enzyme controlled drug release.  Cell studies on cytotoxicity, uptake and subcellular colocalization. Other project: Nanogels for tumor vaccination  Chemical modification and characterization of proteins (antigens).  Design, development and characterization of responsive nanogels for proteins (antigens), including protein (antigen)-nanogel conjugates via disulfide bonds and disulfide-crosslinked polymer shell coated nanogels. Show less



China Pharmaceutical University

• Nanjing, Jiangsu, China

• Master

  • Sep 2009 - Jun 2012

  Development of modified albumin nanoparticles as a novel drug carrier for brain delivery  Development and characterization of (active targeted) DOX-loaded albumin nanoparticles.  Cell study on cytotoxicity, uptake and development of blood-brain barrier in vitro model.  Development of glioma animal model.  Evaluate in vivo pharmacokinetics and biodistribution. Development of solid dispersions for insoluble drug  Development and characterization of different crystal forms of insoluble drug Lonidamine Show less



China Pharmaceutical University

• Nanjing, Jiangsu, China

• Intern

  • Jan 2009 - Jun 2009

  Internship: Establishment of quality standard of Liushen (a traditional Chinese medicine) buccal tablets  Isolation and characterization of main components in Liushen buccal tablets. Internship: Establishment of quality standard of Liushen (a traditional Chinese medicine) buccal tablets  Isolation and characterization of main components in Liushen buccal tablets.