Yichen Zhang

Statistician, Machine Learning Researcher at BC Cancer
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Contact Information
Location
Greater Vancouver Metropolitan Area, CA
Languages
  • Chinese Native or bilingual proficiency
  • Engligh Full professional proficiency
  • Spanish Elementary proficiency

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Patrick Danaher

Yichen was an intern in my department during his grad school tenure. Although he'd barely begun his training at the time, he was a quick study, going deep in both software development and in running complex Bayesian models. His internship provided me with enough data to conclude that he's 1. incredibly smart, 2. very professional, and 3. a pleasure to work with.

Afshin Mashadi-Hossein

I had the pleasure of working with Yichen closely. He consistently impressed the team with his commitment to see projects through to completion. He brought a positive attitude, attention to details and valuable insights to every interaction. Yichen’s drive, expertise in computational sciences, deep knowledge of omics research and most importantly collegial attitude will make him a valuable member of any team.

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Experience

    • Canada
    • Hospitals and Health Care
    • 700 & Above Employee
    • Statistician, Machine Learning Researcher
      • Apr 2019 - Present

      - Research on Interpretable Latent Variable Model for High-dimensional Biology - Proposed and developed a deep-learning-based probabilistic topic model to unveil dynamic transcriptomic patterns, first-author publication in Cell Genomics. - Developed a Python package deltatopic to implement topic analysis for single-cell data - Developed a deep learning approach for interpretable representation of gene expression, selected for presentation at ISBM conference, Machine Learning in… Show more - Research on Interpretable Latent Variable Model for High-dimensional Biology - Proposed and developed a deep-learning-based probabilistic topic model to unveil dynamic transcriptomic patterns, first-author publication in Cell Genomics. - Developed a Python package deltatopic to implement topic analysis for single-cell data - Developed a deep learning approach for interpretable representation of gene expression, selected for presentation at ISBM conference, Machine Learning in Computational and Systems Biology (MLCSB) track. - Collaborated on a tree-structured latent topic model to derive hierarchical structures for immune activities; paper submitted. Show less - Research on Interpretable Latent Variable Model for High-dimensional Biology - Proposed and developed a deep-learning-based probabilistic topic model to unveil dynamic transcriptomic patterns, first-author publication in Cell Genomics. - Developed a Python package deltatopic to implement topic analysis for single-cell data - Developed a deep learning approach for interpretable representation of gene expression, selected for presentation at ISBM conference, Machine Learning in… Show more - Research on Interpretable Latent Variable Model for High-dimensional Biology - Proposed and developed a deep-learning-based probabilistic topic model to unveil dynamic transcriptomic patterns, first-author publication in Cell Genomics. - Developed a Python package deltatopic to implement topic analysis for single-cell data - Developed a deep learning approach for interpretable representation of gene expression, selected for presentation at ISBM conference, Machine Learning in Computational and Systems Biology (MLCSB) track. - Collaborated on a tree-structured latent topic model to derive hierarchical structures for immune activities; paper submitted. Show less

    • Canada
    • Higher Education
    • 700 & Above Employee
    • Senior Statistical Consultant
      • Apr 2019 - Present

      - Helped clients to formulate research proposals, study design, and appropriate statistical methodologies. - Conducted data analyses across various study designs, using models such as GLMs, mixed effects, and survival proportional hazards. - Wrote statistical reports. - Supervised junior consultants.

    • Senior Teaching Assistant
      • Sep 2018 - Apr 2019

      Head and co-head TA for multiple statistics courses.

    • Canada
    • Telecommunications
    • 500 - 600 Employee
    • Machine Learning Researcher
      • Apr 2022 - Aug 2022

      - Achieved 2nd place in the CVPR ActivityNet Challenge focusing on Temporal Action Localization. - Fine-tuned and aggregated multiple video classification models, including Timesformer and Video Swin Transformer, for improved performance on video classification. - Achieved 2nd place in the CVPR ActivityNet Challenge focusing on Temporal Action Localization. - Fine-tuned and aggregated multiple video classification models, including Timesformer and Video Swin Transformer, for improved performance on video classification.

    • United States
    • Biotechnology Research
    • 500 - 600 Employee
    • Biostatistician
      • Oct 2017 - Jun 2018

      - Collaborated with a pharmaceutical company on a report to the FDA; my duty included implementing posterior inference and performing model diagnosis to validate a Bayesian hierarchical model. - Developed a data pipeline using Shiny for efficient data storage, formatting, and statistical reporting. - Proposed a cell deconvolution method for NanoString data, improved on existing method in higher accuracy. - Provided statistical consulting, implemented and interpreted the results of… Show more - Collaborated with a pharmaceutical company on a report to the FDA; my duty included implementing posterior inference and performing model diagnosis to validate a Bayesian hierarchical model. - Developed a data pipeline using Shiny for efficient data storage, formatting, and statistical reporting. - Proposed a cell deconvolution method for NanoString data, improved on existing method in higher accuracy. - Provided statistical consulting, implemented and interpreted the results of statistical models, including Elastic net and survival analysis. Show less - Collaborated with a pharmaceutical company on a report to the FDA; my duty included implementing posterior inference and performing model diagnosis to validate a Bayesian hierarchical model. - Developed a data pipeline using Shiny for efficient data storage, formatting, and statistical reporting. - Proposed a cell deconvolution method for NanoString data, improved on existing method in higher accuracy. - Provided statistical consulting, implemented and interpreted the results of… Show more - Collaborated with a pharmaceutical company on a report to the FDA; my duty included implementing posterior inference and performing model diagnosis to validate a Bayesian hierarchical model. - Developed a data pipeline using Shiny for efficient data storage, formatting, and statistical reporting. - Proposed a cell deconvolution method for NanoString data, improved on existing method in higher accuracy. - Provided statistical consulting, implemented and interpreted the results of statistical models, including Elastic net and survival analysis. Show less

Education

  • The University of British Columbia
    Doctor of Philosophy - PhD, Statistics
    2018 - 2024
  • University of Washington
    Master of Science - MS (Thesis), Biostatistics
    2016 - 2018
  • Wuhan University
    Bachelor of Science (BS), Mathematics and Applied Mathematics
    2012 - 2016
  • Hangzhou No.2 High School
    2009 - 2012

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