Xuemei He
VP of Purification Technologies at GenScript- Claim this Profile
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Bio
Experience
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GenScript
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United States
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Biotechnology Research
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400 - 500 Employee
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VP of Purification Technologies
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2023 - Present
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Quintara Biosciences
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United States
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Biotechnology Research
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1 - 100 Employee
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VP of Research and Operations
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Sep 2023 - Nov 2023
Sanger sequencing, Nanopore sequencing (whole plasmid), DNA preps (plasmids and circular single stranded DNAs) Sanger sequencing, Nanopore sequencing (whole plasmid), DNA preps (plasmids and circular single stranded DNAs)
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Full Circles Therapeutics
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Albany, California, United States
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VP of Process Development, Head of California Site Operation
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Sep 2022 - Nov 2023
• https://www.linkedin.com/company/full-circles-therapeutics-inc/ • Site operation • Upstream/downstream process development/QC assay development and qualification • Plasmids and circular single stranded DNA purification/production • Protein purification and production • M13 Phage particles production (Culturing and purification) • https://www.linkedin.com/company/full-circles-therapeutics-inc/ • Site operation • Upstream/downstream process development/QC assay development and qualification • Plasmids and circular single stranded DNA purification/production • Protein purification and production • M13 Phage particles production (Culturing and purification)
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NanoMicro Technologies Inc.
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China
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Chemical Manufacturing
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1 - 100 Employee
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Deputy General Manager, Applications, Collaborations, and Development Strategy
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Jan 2022 - Aug 2022
• Leading the application team to develop tests guiding new product development; exploring new applications for existing products to support Marketing and Sales • Promoting collaboration with major biopharma customers in China • Providing technical leadership and consultation to company’s strategic development especially in the field of downstream purification business. • Leading the application team to develop tests guiding new product development; exploring new applications for existing products to support Marketing and Sales • Promoting collaboration with major biopharma customers in China • Providing technical leadership and consultation to company’s strategic development especially in the field of downstream purification business.
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Bio-Rad Laboratories
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United States
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Biotechnology Research
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700 & Above Employee
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Chromatography media chemistry R&D manager II
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Mar 2015 - Jan 2022
Applications of chromatography in downstream processing: Purification of biologics (Monoclonal antibodies/fusions/fragments/ADCs, recombinant proteins/enzymes, Adenovirus and Adeno-associated virus (viral vectors) for gene therapy, virus particles/VLPs for vaccination, and long-length mRNAs) from microbial/insect/mammalian culture harvests; solubilization, purification and refolding of proteins from inclusion bodies; clearance of process and product-related impurities.; viral clearance and… Show more Applications of chromatography in downstream processing: Purification of biologics (Monoclonal antibodies/fusions/fragments/ADCs, recombinant proteins/enzymes, Adenovirus and Adeno-associated virus (viral vectors) for gene therapy, virus particles/VLPs for vaccination, and long-length mRNAs) from microbial/insect/mammalian culture harvests; solubilization, purification and refolding of proteins from inclusion bodies; clearance of process and product-related impurities.; viral clearance and safety. Offering complete solutions to clients in biologics processing, including technical consultation on impurity analysis, chemicals and hardware, and process-scale column packing Collaboration with CRO/CMO on the research and development of new product/technology. Development of chromatography media (Affinity, IEX, HIC, Mixed-mode, Ceramic Hydroxyapatite, Metal affinity, and SEC) and disposable columns for the downstream processing of biologics. Responsibilities include screening of prototypes, formulation optimization, technology transfer from R&D to production (Production procedure/QC procedure/SOP), verification and validation of product prototypes at different development phases, trouble-shooting for process & product quality as well as continuous improvement. Working with cross-functional teams of R&D, manufacturing, QA/QC, marketing, sales, and legal departments for product launching and global customer support. Process chromatography facility management (Materials, equipment acquisition and maintenance, lab safety, and waste disposal etc). R&D lab scientists management Technical training to customers and colleagues (Marketing, Sales/Field supports, Tech supports, QC, and Manufacturing) —- lectures and wet labs
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R&D Sr. Staff Scientist
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Mar 2012 - Feb 2015
Development and application of polymeric process chromatography media; technical support; customer education.
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R&D Staff Scientist
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Mar 2006 - Feb 2012
Development and application of polymeric chromatography media; technical support; customer education.
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R&D Sr. Scientist
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Mar 2003 - Feb 2006
Development and application of affinity chromatography media; technical support; customer education.
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R&D Scientist
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Aug 2002 - Feb 2003
Development and application of nucleic acid sample prep products; technical support; customer education.
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The University of Texas at Austin, College of Pharmacy
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United States
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Higher Education
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1 - 100 Employee
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Research Scientist, Lab Manager
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Jan 2001 - Jul 2002
Mechanistic studies of enzyme catalysis Mechanistic studies of enzyme catalysis
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University of Minnesota
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United States
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Higher Education
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700 & Above Employee
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Research Scientist
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Jul 1997 - Dec 2000
Mechanistic studies of enzyme catalysis Mechanistic studies of enzyme catalysis
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Education
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San Diego State University
Advanced Certificate in Regulatory Affairs, GPA 4.0 -
University of Minnesota-Twin Cities
Ph.D., Biological Chemistry -
Zhongshan (Sun Yat-sen) University
Bachelor of Science - BS, Chemistry