Xiomara Perez, PhD

Scientific Manager at Advanced Cell Diagnostics
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Contact Information
us****@****om
(386) 825-5501
Location
San Francisco Bay Area
Languages
  • Spanish Native or bilingual proficiency
  • English Native or bilingual proficiency

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5.0

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Carla Campos, MS, ASP®

Xiomara and I worked in the same team from 2006-2013. Xiomara is one of the most intelligent and hardworking individuals that I have had the privilege of knowing. Her attention to detail and her problem solving abilities make her an asset to any job she chooses to endeavor. Her trustworthy, fun personality, her focus and drive to complete her projects successfully highly motivates those around her. She was always the backbone of the team.

Anne Andrews

Xiomara is an independent researcher who is a creative problem-solver and a leader. She is an experienced neuroscientist and neurochemist and an expert in voltammetry methods in vivo and ex vivo. When she worked with me, she was pivotal in developing and implementing chronoamperometry methods, which she applied to the study of psychiatric and neurodegeneration models. Her work was instrumental in understanding how differences in serotonin transporter expression translate into meaningful changes in uptake function. Xiomara is highly intelligent. This is evident in the way she quickly masters the concepts underlying her research projects. As a student, she pursued the scientific literature at the level we wish all students did. Xiomara is exceptionally mature in her personal conduct and her dealings with other members of the scientific teams she works with. Xiomara was a prestigious Howard Hughes Scholar at Temple University before coming to Penn State, where she was an award-winning doctoral student. I have supervised over 100 graduate and undergraduate students and Xiomara is definitely one of the most gifted and genuinely motivated people I’ve worked with. I would gladly have her as a colleague in an academic, research, or industry setting.

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Experience

    • United States
    • Biotechnology Research
    • 100 - 200 Employee
    • Scientific Manager
      • Oct 2023 - Present

    • Scientific Lead
      • Mar 2021 - Nov 2023

    • Presales Scientific Consultant
      • Aug 2019 - Mar 2021

    • United States
    • Research Services
    • 700 & Above Employee
    • Research Scientist
      • Sep 2009 - Jul 2019

      Principal scientist and co-investigator in projects aiming to identify the striatal pathways and cholinergic receptor subtypes through which exposure to nicotine and other cholinergic compounds alters dopamine signaling. This work is essential to elucidate the mechanisms by which these drugs can protect against neurodegeneration, have a therapeutic effect on drug-induced dyskinesias and alter brain chemistry to induce nicotine dependence. This research involved a combination of behavioral… Show more Principal scientist and co-investigator in projects aiming to identify the striatal pathways and cholinergic receptor subtypes through which exposure to nicotine and other cholinergic compounds alters dopamine signaling. This work is essential to elucidate the mechanisms by which these drugs can protect against neurodegeneration, have a therapeutic effect on drug-induced dyskinesias and alter brain chemistry to induce nicotine dependence. This research involved a combination of behavioral, molecular and functional assays (such as in vivo optogenetics, chemogenetics, cyclic voltammetry and immunohistochemistry) to gain a better understanding of the underlying mechanisms behind these disorders and identify novel drug targets. Show less Principal scientist and co-investigator in projects aiming to identify the striatal pathways and cholinergic receptor subtypes through which exposure to nicotine and other cholinergic compounds alters dopamine signaling. This work is essential to elucidate the mechanisms by which these drugs can protect against neurodegeneration, have a therapeutic effect on drug-induced dyskinesias and alter brain chemistry to induce nicotine dependence. This research involved a combination of behavioral… Show more Principal scientist and co-investigator in projects aiming to identify the striatal pathways and cholinergic receptor subtypes through which exposure to nicotine and other cholinergic compounds alters dopamine signaling. This work is essential to elucidate the mechanisms by which these drugs can protect against neurodegeneration, have a therapeutic effect on drug-induced dyskinesias and alter brain chemistry to induce nicotine dependence. This research involved a combination of behavioral, molecular and functional assays (such as in vivo optogenetics, chemogenetics, cyclic voltammetry and immunohistochemistry) to gain a better understanding of the underlying mechanisms behind these disorders and identify novel drug targets. Show less

    • United States
    • Wellness and Fitness Services
    • 1 - 100 Employee
    • Staff scientist
      • Jan 2007 - Sep 2009

      Principal investigator in a project funded by the tobacco-Related Disease Research Program aimed to better understand the mechanisms by which nicotine may be neuroprotective in Parkinson's disease. My studies involved the use of functional assays to assess the effect of long-term nicotine exposure on dopamine release before and after dopamine neurodegeneration.

    • Postdoctoral researcher
      • Jan 2005 - Dec 2007

      Established an electrochemical functional assay (slice voltammetry) to study the control that nicotinic receptors exert on dopamine release. This work helped elucidate the nicotinic receptor subtypes regulating striatal dopamine release under physiological conditions and after dopaminergic damage.

    • Research Assistant
      • Aug 1999 - Dec 2004

      Investigated the changes in serotonin and dopamine uptake kinetics in serotonin receptor knockout mice as well as alpha-synuclein mutant mice to enhance our understanding of the involvement of these neurotransmitter systems in psychiatric and movement disorders Investigated the changes in serotonin and dopamine uptake kinetics in serotonin receptor knockout mice as well as alpha-synuclein mutant mice to enhance our understanding of the involvement of these neurotransmitter systems in psychiatric and movement disorders

Education

  • Penn State University
    PhD, Chemistry/Neurochemistry
    1999 - 2004
  • Temple University
    BS, Chemistry
    1997 - 1999
  • Bucks County Community College
    Chemistry
    1995 - 1997

Community

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