Vimal N.

Principal Scientist at Ixora Scientific Inc
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Contact Information
us****@****om
(386) 825-5501
Location
San Diego, California, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Principal Scientist
      • Jul 2022 - Jul 2023

      San Diego, California, United States • Lead ingredient research of natural ingredients through model systems to deliver functional, analytical, and sensorial insights to accelerate global product development • Hands-on experience with quantification of targeted molecules using LCMS-Triple quad, GCMS analysis of flavors • Leverage sound technical approaches to collaborate with internal and external partners to screen and assess new substrates and ingredients’ viability and feasibility • Research and development of novel… Show more • Lead ingredient research of natural ingredients through model systems to deliver functional, analytical, and sensorial insights to accelerate global product development • Hands-on experience with quantification of targeted molecules using LCMS-Triple quad, GCMS analysis of flavors • Leverage sound technical approaches to collaborate with internal and external partners to screen and assess new substrates and ingredients’ viability and feasibility • Research and development of novel food ingredients using different Analytical techniques: LC-UV/CAD, HRMS, LC-MS/MS, NMR etc. • Preparing documents and compiling analytical results to support regulatory (e.g. for GRAS and EFSA) filing testing. • Extraction, purification, and identification of active ingredients from plants/botanical extracts • Extensive experience in software for data processing of Chromleon Empower, Xcalibur, Thermo SII, Labsolutions, Chemstation, Hystar and other instrument software. • NMR characterization of new natural molecule responsible for taste modulations. • Design and execute experiments, and analyze and interpret data to make sound technical rec-ommendations on ingredient viability and feasibility. • Act as a technical subject matter expert for ingredient functionality • Keeping lab notebook and communicating with team and stakeholders. • Mentoring junior scientists Show less

    • France
    • Personal Care Product Manufacturing
    • 700 & Above Employee
    • Senior Manager - Analytical Chemistry
      • May 2019 - Jun 2022

      • Leading disruptive innovation project for natural biomarker detection non-invasively and working towards the goal of making a smart tool/or an app, (inspired by GLUCOWATCH) • Managing natural extract community working groups (mainly India, France and China) to support different domains to improve the way of working viz. harmonization of methods, quality, chemical composition and safety. • Setting up platform for natural polymers like polysaccharides… Show more • Leading disruptive innovation project for natural biomarker detection non-invasively and working towards the goal of making a smart tool/or an app, (inspired by GLUCOWATCH) • Managing natural extract community working groups (mainly India, France and China) to support different domains to improve the way of working viz. harmonization of methods, quality, chemical composition and safety. • Setting up platform for natural polymers like polysaccharides using green chemistry and working on a project based on transforming monomers like simple polyalcohol's to polymers using green chemistry approach and characterizing new biodegradable modified polyols/polysaccharides using various analytical techniques like SEC-GPC, NMR, IC, DSC etc.. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoc/Senior Research Associate
      • May 2012 - May 2019

      College Station • Identification and screening of plant extracts, fractionating its chemical components for bioassay with the help of flash, RP-18, silica, LH-20 Sephadex and TLC. • Working with automated fractionation systems like Gilson liquid handler and ISCO combiflash. • Dereplication of natural products using LCMS and MS/MS fragmentation approach. • Structure elucidation of organic compounds, small molecules and natural products characterization using high resolution NMR & 2DNMR spectroscopy… Show more • Identification and screening of plant extracts, fractionating its chemical components for bioassay with the help of flash, RP-18, silica, LH-20 Sephadex and TLC. • Working with automated fractionation systems like Gilson liquid handler and ISCO combiflash. • Dereplication of natural products using LCMS and MS/MS fragmentation approach. • Structure elucidation of organic compounds, small molecules and natural products characterization using high resolution NMR & 2DNMR spectroscopy (Bruker & Varian), high resolution MS, ion trap MS, X-ray crystallographic techniques and circular dichroism. • Experience in setting NMR experiments and using Mestronova, Bruker, and Agilent softwares. • Performing experiments for analytical method development/qualification/validation and charac-terization for crude extracts of natural products using HPLC and semi prep-HPLC. • Identification of essential oils, non-polar terpenes by GCMS. • Chemical analysis and extraction of natural product from various sources to provide information on compounds such as total phenolics using Folin ciocalteu method, measuring antioxidant activity by ORAC and total carotenoid content by spectrophotometric methods. • Working with cell lines and experience in working with biochemical assays like ELISA, NO and ROS • Developing techniques for extraction by steam distillation, liquid-liquid extraction, supercritical or other methodologies. . • Working collaboratively in cross-functional teams. • Experience in working with databases like DNP, AntiMarin, NIST, JP mass bank etc. • Troubleshoot and maintenance of analytical instruments as needed. Show less

    • United States
    • Research Services
    • 700 & Above Employee
    • Post doc
      • Mar 2011 - May 2012

      Center for Marine Biotechnology and Biomedicine Research methodology Marine microbial metabolites for Anti Cancer and kinase target •The projects involved identification of novel bioactive natural products from marine microorganisms by using analytical techniques like LCMS and HPLC. •Structure elucidation of compounds were achieved by bioassay guided silica gel chromatography/RP-18 followed by preperative HPLC and characterization by NMR spectroscopy.

    • India
    • Biotechnology Research
    • 400 - 500 Employee
    • Science Associate - Medicinal Chemistry
      • 2004 - 2007

      Greater Bengaluru Area Medicinal Chemistry Synthesis

    • India
    • Chemical Manufacturing
    • 700 & Above Employee
    • Research Associate
      • Jun 2003 - Dec 2003

      Kalyan Area, India Synthesis of Venlafaxine and derivatives

Education

  • Georg-August-Universität Göttingen
    PhD, Natural products Chemistry (Secondary metabolites from Microbes)
    2007 - 2011
  • Texas A&M University
  • University of Mumbai
    Bachelors and Master's degree, Organic Chemistry
  • Georg-August-Universität Göttingen
  • UC San Diego

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