Vien Le

Research Scientist at Inception Therapeutics
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Contact Information
us****@****om
(386) 825-5501
Location
San Diego, California, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Scientist
      • May 2021 - Present

      San Diego, California, United States

    • Research Scientist
      • Nov 2020 - May 2021

      San Diego, California, United States

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Postdoctoral Researcher
      • Oct 2016 - Nov 2020

      Duarte, California, United States - Developed and executed experiments involving prostate cancer and prostate development by using novel and cutting-edge approaches. - By using Genetically Engineered Mouse Model (GEMM) we answered the questions about mechanisms of P10 and E-cadherin in the prostate cancer initiation and progression. - In another GEMM, we filled the gap of the knowledge about the decisive role of androgen receptor in mesenchymal cells, in particularly in Gli1-expressing cells, in prostate initiation… Show more - Developed and executed experiments involving prostate cancer and prostate development by using novel and cutting-edge approaches. - By using Genetically Engineered Mouse Model (GEMM) we answered the questions about mechanisms of P10 and E-cadherin in the prostate cancer initiation and progression. - In another GEMM, we filled the gap of the knowledge about the decisive role of androgen receptor in mesenchymal cells, in particularly in Gli1-expressing cells, in prostate initiation, development, regeneration and cancer. - Optimized and troubleshooted up-to-date techniques including preparing samples for single cell sequencing and ChIP-seq with low cell number, to determine the crucial functions and correlation of androgen receptor and Sonic hedgehog signaling pathways in androgen-induced prostate cell fate and growth. - Hands on experiments such as xenograft, 3D organoid culture, and tissue culture (ex-vivo) to assess the effects of pharmaceutical materials on prostate development. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Researcher
      • Feb 2013 - Feb 2016

      San Francisco General Hospital - Work with multiple rabbit models to identify the pathogenesis of Staphylococcus aureus in various infections, including skin and skin structure, pneumonia, endocarditis and joint knee infections. - Collaborate with companies to assess the novel antibodies and/or antibiotics (tedizolid) for treatment of Staphylococcus aureus infections in different in-vivo models. - Keep up-to-date knowledge and apply to current research which generate live-attenuated Staphylococcus aureus vaccine base… Show more - Work with multiple rabbit models to identify the pathogenesis of Staphylococcus aureus in various infections, including skin and skin structure, pneumonia, endocarditis and joint knee infections. - Collaborate with companies to assess the novel antibodies and/or antibiotics (tedizolid) for treatment of Staphylococcus aureus infections in different in-vivo models. - Keep up-to-date knowledge and apply to current research which generate live-attenuated Staphylococcus aureus vaccine base on the updated knowledge using the knock-out methods. Show less

    • Vietnam
    • Research Services
    • 200 - 300 Employee
    • Associate Researcher
      • Sep 2004 - May 2008

      Ho Chi Minh City, Vietnam - Expertise in microbiology knowledge and techniques. - Determine the prevalence of Streptococcus pneumoniae serotypes from young school children to prepare for the vaccine project using molecular assay not excluded to MLST and sequencing analysis.

Education

  • Oxford University
    Doctor of Philosophy (PhD), Clinical Medicine
    2008 - 2012

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