Experience

ACELYRIN, INC.

• United States
• Biotechnology Research
• 1 - 100 Employee

• Sr Manager (Supply Chain)

  • Apr 2023 - Present

  Thousand Oaks, California, United States Leading logistics, demand planning, and inventory management.



Amgen

• United States
• Biotechnology Research
• 700 & Above Employee

• Manager (Clinical Supply Chain Lead)

  • Jan 2022 - Apr 2023

  Thousand Oaks, California, United States • Clinical Supply Chain Leader for 5 products including commercial LCM products Repatha and XGEVA to oversee and strategize end to end clinical supply chain activities including: study set up of IRT at study site, study maintenance to resupply study sites, and scrap management upon completion of the clinical trial. • Managed demand, forecasts, and inventory to support various clinical phases, from FIH to phase 3 and lifecycle management activities (LCMs). • Identified risks in supply… Show more • Clinical Supply Chain Leader for 5 products including commercial LCM products Repatha and XGEVA to oversee and strategize end to end clinical supply chain activities including: study set up of IRT at study site, study maintenance to resupply study sites, and scrap management upon completion of the clinical trial. • Managed demand, forecasts, and inventory to support various clinical phases, from FIH to phase 3 and lifecycle management activities (LCMs). • Identified risks in supply strategy and planned backup strategies as needed to ensure supply to patient. Examples include material nearing expiry and requiring resupply fills to be moved up or working with increased lead times from raw material suppliers, requiring procurement activities to occur ahead of schedule. • Created onboarding playbook for clinical supply chain leads to address 67% growth in the team and ensure success in each lead’s onboarding effectiveness.

• Sr. Associate (Supply Chain Security)

  • Jan 2020 - Jan 2022

  Thousand Oaks, CA, United States • Led the integration of Amgen Thousand Oaks’ Transportation Hub from Process Development into Global Supply Chain to standardize lane management processes and internal shipment service level agreements for greater efficiency and productivity output. • Managed the Air 2 Ocean Initiative across cross functional teams including quality, transportation, and commercial planning to implement ocean lanes for high volume lanes. Saved $2.7M in 2021, and forecasted $8M savings in 2022.… Show more • Led the integration of Amgen Thousand Oaks’ Transportation Hub from Process Development into Global Supply Chain to standardize lane management processes and internal shipment service level agreements for greater efficiency and productivity output. • Managed the Air 2 Ocean Initiative across cross functional teams including quality, transportation, and commercial planning to implement ocean lanes for high volume lanes. Saved $2.7M in 2021, and forecasted $8M savings in 2022. • Managed KPIs for Supply Chain Security by creating a Tableau dashboard to automate data inputs and generate visualizations for management to review product diversion, theft, counterfeits, and lost/missing as needed. • Created security audit program risk framework and implemented security audit schedule to track all relevant supplier compliance (LSPs, TSPs, Contract Manufacturers, Return & Destruction, CCL manufacturers, etc).

• Sr. Associate Scientist (Drug Product)

  • May 2019 - Jan 2020

  Thousand Oaks, California • Performed long term formulation verification to support FIH filing for Bispecific T cell Engager (BiTE®) and modified IgG. Tasked with DOE to evaluate molecule stability and expiry of drug product in lyophilized state. • Tested biophysical properties and provided documentation for tech transfer into manufacturing for filling and vialing to produce drug product for toxicology and clinical studies. • Executed compatibility studies at low concentrations including short term evaluation in… Show more • Performed long term formulation verification to support FIH filing for Bispecific T cell Engager (BiTE®) and modified IgG. Tasked with DOE to evaluate molecule stability and expiry of drug product in lyophilized state. • Tested biophysical properties and provided documentation for tech transfer into manufacturing for filling and vialing to produce drug product for toxicology and clinical studies. • Executed compatibility studies at low concentrations including short term evaluation in syringes, and in IV bags. • Investigated process related effects on properties like charge variance during UF/DF due to high concentration, and interaction with DS bags material for possible particle formation or protein loss. • Presented at product team meetings with global operations lead to provide interim updates and discuss expectations for incoming pipeline activities.

• Associate Scientist (Discovery Research)

  • Jun 2017 - May 2019

  Thousand Oaks, California • Performed high-throughput assays (LC, CE-SDS, LC-MS, DLS, DSF/DSC) across mAb variants to trend structural and biochemical strengths & weaknesses in engineered proteins designed for future pipeline programs. Analyzed panels of over 100 variants per week. • Studied thermal stability on mAb panels with short term stress & degradation to give insight on manufacturability and rank the top molecules for handing off to process development in preparation for scaled up GMP production. Delivered… Show more • Performed high-throughput assays (LC, CE-SDS, LC-MS, DLS, DSF/DSC) across mAb variants to trend structural and biochemical strengths & weaknesses in engineered proteins designed for future pipeline programs. Analyzed panels of over 100 variants per week. • Studied thermal stability on mAb panels with short term stress & degradation to give insight on manufacturability and rank the top molecules for handing off to process development in preparation for scaled up GMP production. Delivered 2-3 molecule assessment packages per quarter. • Served as analytical team lead for bispecific program in research. Responsibilities included DOE, communicating updates with upstream leads, and proposing top candidates. • Collaborated with Drug Product and Attribute Sciences on technology development to implement CE-MS (zipchip), and Maurice cIEF to identify isoforms specifically observed in bispecific molecules. • Instrument owner responsible for maintaining instruments and tracking preventative maintenance schedules for lab equipment including LC, CE, Tecan, and pipettes to prevent disruption of pipeline work.



Eurofins Lancaster Laboratories

• United States
• Biotechnology Research
• 700 & Above Employee

• Scientist II (Attribute Sciences)

  • Dec 2016 - Jun 2017

  Thousand Oaks, California

• Scientist I

  • Feb 2015 - Dec 2016

  Thousand Oaks, California • Performed analytical LC methods on protein samples to support clone selection, toxicology studies, and pilot plant manufacturing runs. • Executed method verification of titer and size exclusion assays for assay specificity, robustness, linearity, and repeatability to support release testing of incoming pipeline protein therapeutics. • Completed method transfer for implementation of new Total Organic Carbon (TOC) equipment, and protocols to QC for improved sample throughput.