Vengadeshprabhu Karuppagounder

Scientist II at Juvena Therapeutics
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Location
Hershey, Pennsylvania, United States, US
Languages
  • Tamil Native or bilingual proficiency
  • English Full professional proficiency

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientist II
      • Mar 2023 - Present
    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Researcher
      • Dec 2017 - Feb 2023

      • Novel findings present elevated GRK2 signaling in chondrocytes as a driver of cartilage degradation and paroxetine as a disease-modifying drug for synovitis and Osteoarthritis treatment • Established new methods to study the role of GRK2 signaling in macrophage/immune cells in aging mouse models. • Achieved First author in leading scientific journals, Science Translational Medicine, & International Journal of Molecular Sciences. As a co-author, I have published several research articles. • Exhibited excellent working skills ranging from developing comprehensive project plans, formulating hypotheses, result-oriented experimentation, data interpretation and analysis. Show less

    • Research Associate
      • Dec 2012 - Mar 2017

      • Our novel findings discovered small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats • We identified the HMGB1 signaling drive an important role in skin inflammation, and quercetin/resveratrol treatments could be a promising agent for atopic dermatitis. • Also, independently investigated the cancer drug induced nephrotoxicity and cardiotoxicity in animal models and treatment options. • Gained in-depth research experience in the field of pharmacology, immunology, and molecular biology, transgenic animal model and fluorescent/confocal imaging techniques. Show less

    • Lecturer
      • Sep 2010 - Oct 2012
    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Medical Representative
      • Sep 2007 - May 2008

Education

  • Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan
    Doctor of Philosophy (Ph.D.), Pharmacology
    2013 - 2017
  • K.M.C.H. COLLEGE OF PHARMACY (Inst. Code - 114), COIMBATORE
    Master’s Degree, Pharmaceutical Sciences
    2008 - 2010
  • K.M.C.H. COLLEGE OF PHARMACY (Inst. Code - 114), COIMBATORE
    Bachelor’s Degree, Pharmaceutical Sciences
    2003 - 2007

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