Varsha Sreekanth
Bioinformatics Analyst at University of Colorado Anschutz Medical Campus- Claim this Profile
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Bio
Experience
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University of Colorado Anschutz Medical Campus
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United States
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Higher Education
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700 & Above Employee
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Bioinformatics Analyst
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May 2020 - Present
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MIT Koch Institute for Integrative Cancer Research
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United States
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Research Services
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100 - 200 Employee
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Bioinformatics Intern
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Sep 2019 - Dec 2019
• Processed single-cell RNAseq datasets in R using Seurat • Working closely with understanding Convolutional Neural Network models (CNNs) and applying them to genomic data to solve classification problems like assessing chromatin accessibility • Processed single-cell RNAseq datasets in R using Seurat • Working closely with understanding Convolutional Neural Network models (CNNs) and applying them to genomic data to solve classification problems like assessing chromatin accessibility
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Summer Intern
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May 2019 - Aug 2019
Applied transcript reconstruction algorithms, by integrating various RNA-seq public datasets, to assemble mouse liver transcriptomeIntegrated the discovered lncRNAs with the in-house RNA-seq pipeline, to study their role in liver, post exposure to environmental chemicals Applied transcript reconstruction algorithms, by integrating various RNA-seq public datasets, to assemble mouse liver transcriptomeIntegrated the discovered lncRNAs with the in-house RNA-seq pipeline, to study their role in liver, post exposure to environmental chemicals
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Project Intern
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Jun 2018 - Aug 2018
Determined the structure of WDR13 protein by homology modeling and threading and validated the structure using Ramachandran Plot.Analyzed role of WDR13 in eye-related disorders to determine potential drug targets.Performed molecular dynamic simulation for WDR13 to study conformational changes; studied its interactions with other proteins using Pymol and Autodock. Determined the structure of WDR13 protein by homology modeling and threading and validated the structure using Ramachandran Plot.Analyzed role of WDR13 in eye-related disorders to determine potential drug targets.Performed molecular dynamic simulation for WDR13 to study conformational changes; studied its interactions with other proteins using Pymol and Autodock.
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University of Madras
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India
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Higher Education
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500 - 600 Employee
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Research Assistant
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Dec 2017 - Apr 2018
Studied the impact of APOBEC3A/3B Deletion Polymorphism on miRNA mediated regulation of APOBEC3A and APOBEC3B in cervical cancer. Studied the impact of APOBEC3A/3B Deletion Polymorphism on miRNA mediated regulation of APOBEC3A and APOBEC3B in cervical cancer.
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Indian Council of Agricultural Research (ICAR)
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Government Administration
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200 - 300 Employee
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Intern
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Jun 2017 - Jul 2017
Characterized genomes of sugarcane varieties by genomic in-situ hybridization (GISH)Pin pointed chromosome count of various Indian sugarcane varieties by karyotyping. Characterized genomes of sugarcane varieties by genomic in-situ hybridization (GISH)Pin pointed chromosome count of various Indian sugarcane varieties by karyotyping.
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Education
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Boston University
Master of Science - MS, Bioinformatics -
Anna University
Bachelor's degree, Biotechnology