Vanessa Marfil Vives

Medical Writer at MEDICAL SCIENCE CONSULTING (MSC)
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Contact Information
us****@****om
(386) 825-5501
Location
Greater Valencia Metropolitan Area, ES
Languages
  • Español -
  • Catalán -
  • Inglés -

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Experience

    • Spain
    • Pharmaceutical Manufacturing
    • 1 - 100 Employee
    • Medical Writer
      • May 2018 - Present

    • Spain
    • Fundraising
    • 1 - 100 Employee
    • Freelance Proposal Writer
      • Apr 2018 - Oct 2018

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Associate
      • Aug 2015 - Sep 2017

      Every year more than 12000 new cases of spinal cord injuries are diagnosed in the US. Although there is no actual cure, in some cases there is a recovery in locomotion. However little is still known about how the recovery process works. By using the simple neuronal system of the nematode C. elegans we are studying how locomotion is affected by neuronal damage and subsequent regeneration. Every year more than 12000 new cases of spinal cord injuries are diagnosed in the US. Although there is no actual cure, in some cases there is a recovery in locomotion. However little is still known about how the recovery process works. By using the simple neuronal system of the nematode C. elegans we are studying how locomotion is affected by neuronal damage and subsequent regeneration.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Researcher
      • Oct 2011 - Jul 2015

      Using the nematode C. elegans we studied the molecular basis of Alzheimer's disease (AD). The presence of amyloid plaques, whose major component is a cleavage product of the amyloid precursor protein (APP), is one of the neuropathological features found in patients with Alzheimer’s disease. However, the physiological function of APP remains unclear. To gain insights into the role of APP, we are studying apl-1, the APP ortholog in C. elegans. apl-1 is essential for viability and its activity affects multiple metabolic processes by interacting with the insulin IIS/daf-2 and heterochronic pathways. My main project focused on finding proteins that can be affecting apl-1 functionality. We found that the receptor protein tyrosine phosphatase MOA-1 (modifier of apl-1) may be important regulating apl-1 function. Using different techniques (such as genetic screenings, generation of transgenic lines by microinjection, RNAi, qPCRs, behavioural assays...) we have found that moa-1 and apl-1 interact genetically affecting the insulin and heterochronic pathways.

    • Lecturer
      • Aug 2014 - Jun 2015

      Teaching Fundamentals of Biology course to College students

    • Spain
    • Research Services
    • 300 - 400 Employee
    • Postdoc Researcher
      • Feb 2011 - Jul 2011

      Study of the cohesin protein complex and the diseases associated with them, specifically Cornelia de Lange syndrome. We worked both with patient derived cell lines and Saccharomyces cerevisiae. Also, performed whole exome sequencing. Study of the cohesin protein complex and the diseases associated with them, specifically Cornelia de Lange syndrome. We worked both with patient derived cell lines and Saccharomyces cerevisiae. Also, performed whole exome sequencing.

    • Spain
    • Higher Education
    • 700 & Above Employee
    • PhD student
      • Jan 2005 - Jul 2010

      Study of the transcription factor HHex, essential for liver development by using cell lines and mouse embryos.Defended my PhD titled: " Characterization of novel Hhex partners: SOX13 and c-Myc. New mechanism for the regulation of Wnt/TCF and c-Myc pathways". Study of the transcription factor HHex, essential for liver development by using cell lines and mouse embryos.Defended my PhD titled: " Characterization of novel Hhex partners: SOX13 and c-Myc. New mechanism for the regulation of Wnt/TCF and c-Myc pathways".

Education

  • Universitat Pompeu Fabra
    Doctor of Pharmacy (Pharm.D.), Cell/Cellular and Molecular Biology
    2005 - 2010
  • Universitat de Barcelona
    Teaching Certificate /CAP
    2006 - 2006
  • Universitat de Barcelona
    Animal Care Certification
    2005 - 2005
  • Universitat Autònoma de Barcelona
    Bachelor's degree, Biochemistry
    2000 - 2004

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