Experience

Oncodesign Precision Medicine - OPM

• France
• Biotechnology Research
• 1 - 100 Employee

• OncoSNIPE programme Director

  • Sep 2022 - Present

  France OncoSNIPE® a French Consortium partly financed by PIA-PSPC - Programme designed to identify and characterize patients resistant to cancer treatments based on Artificial Intelligence. Clinical study NCT04548960 with an enrollment plan of 600 chemo-naive patients NSC-Lung | TN-Breast | Pancreatic cancer with heteromodal and longitudinal monitoring at the time of diagnosis, best therapeutic responses and relapse. Conception, Set-up, Operational and Clinical management of the… Show more OncoSNIPE® a French Consortium partly financed by PIA-PSPC - Programme designed to identify and characterize patients resistant to cancer treatments based on Artificial Intelligence. Clinical study NCT04548960 with an enrollment plan of 600 chemo-naive patients NSC-Lung | TN-Breast | Pancreatic cancer with heteromodal and longitudinal monitoring at the time of diagnosis, best therapeutic responses and relapse. Conception, Set-up, Operational and Clinical management of the OncoSNIPE project, 12 M€, 4 industrials partners, 27 clinical centers and the Unicancer Federation.

• Head of Data Science Lab

  • Sep 2022 - Present

  France Development of OncoSNIPER platform, Target discovery and assessment AI platform. Member of AIDD4H Artificial Intelligence in Drug Discovery for Health, Labcom.



Université de Bourgogne

• France
• Higher Education
• 700 & Above Employee

• Guest Lecturer - DU Artificial Intelligence in Health - Medical School Dijon- Burgundy University

  • Sep 2020 - Present

  Applications and principles of AI in cancer research and Exploitation of structured and unstructured data.



4SBio

• France
• Pharmaceutical Manufacturing

• CEO and Founder

  • Dec 2013 - Present

  France 4SBio is a services company specialized in computational analysis for life sciences data. We aim to translate customers’ needs into efficient and structured process that truly helps to make sense of customers’ data. We provide services in the fields of management, life sciences data analysis including bioinformatics and biostatistics with a deep expertise in biomarker research validation. We also propose custom-tailored training for scientist.



Oncodesign

• France
• Biotechnology Research
• 1 - 100 Employee

• Head of Data Sciences Lab - AI Business Unit at Oncodesign

  • Apr 2021 - Sep 2022

  Dijon, Bourgogne-Franche-Comté, France

• OncoSNIPE® Programme Director

  • Apr 2017 - Sep 2022

  OncoSNIPE® is designed to identify and characterize patients resistant to cancer treatments. Clinical enrollment plan with 600 patients (NSCLC | TNBC | Pancreatic Cancer) ; Longitudinal monitoring at the time of diagnosis, best therapeutic responses and relapse. NCT04578960 Bioinformatics, Artificial Intelligence, Statistical Learning and Semantic Enrichment. Data Governance | GDPR

• Head of Data Science Labs

  • May 2018 - Apr 2021

  Data Science Laboratories set-up and management Member of AIDD4H Artificial Intelligence in Drug Discovery for Health, Labcom (ANR call) initiated in 2021 by Oncodesign and Distributed Knowledge and Artificial Intelligence (CIAD-EA 7533) Laboratory Development of OncoSNIPER platform, Target discovery and assessment AI platform.

• OncoSNIPE® Project Leader / Translational Data Science Project Leader

  • Mar 2015 - Mar 2017

  Dijon Area, France



Abbott Laboratories - Laboratoires Fournier SA

• Head of Bioinformatics facility

  • Jan 2003 - Sep 2013

  Biostatistician (research and pre-clinical) 2007-2013: Experimental design, statistical approaches, resources management, and interpretation. - Development and implementation of R packages for HTS-HCS platform. - Omics (Transcriptomics, Epigenetic modulation, Metabolomics) analysis within renal fibrosis, parkinson, alzheimer, schizophrenia, atherosclerosis and diabetes programs. - Development of analytical approaches for Rare Disease program: Analysis of… Show more Biostatistician (research and pre-clinical) 2007-2013: Experimental design, statistical approaches, resources management, and interpretation. - Development and implementation of R packages for HTS-HCS platform. - Omics (Transcriptomics, Epigenetic modulation, Metabolomics) analysis within renal fibrosis, parkinson, alzheimer, schizophrenia, atherosclerosis and diabetes programs. - Development of analytical approaches for Rare Disease program: Analysis of probe signal done on 25 human primary cell lines. Specialized databases processing for user friendly differentially expressed genes prioritization. Identification of monogenic disorders for different compounds. Bioinformatician (research) 2003-2013: Conception, development, integration, resources management and project leading. - Building up and applying Natural Language Processing to highlight or discover substances which could be used as an indicator of a state. - Implementation of Luxid for life science. - Conception of discovery process for identification of polymorphitic nuclear receptor responsive elements. Based on a new optimizing approaches combined with an environmental promoter study, ProSpER allows managing nuclear receptor with a high recall and specificity level. - Development of a dedicated platform to the cross-omics data analysis. Show less



CLIPP

• United States
• Software Development
• 1 - 100 Employee

• Project Leader

  • Mar 2013 - Aug 2013

  Dijon Area, France Consulting services (Statistical Modelling Master Degree, trainee period): Computational workflow reviewing and implementation of statistical approaches for discovery of proteomics Biomarkers in label-free LC-MS/MS with LTQ Orbitrap Elite.



uhp nancy I

• President of DGIN student association

  • Sep 2002 - Sep 2003

  Organization of the first conference of DGIN - RGTI Master at LORIA-INRIA NANCY GRAND EST : "Bio-informatique Enjeux Actuels".



INRIA Lorraine – Modbio Team

• Bioinformatician Trainee

  • Feb 2002 - Aug 2002

  Comparison of 2 analytical approaches in the search for nucleic pattern. Functional structure of HIV-1, Study of the alternative splicing, starts from 2 approaches, algorithmic and connexionnist.



INRS - Toxicogenomics and Cancerology Lab

• Bioinformatician Trainee

  • Jan 2001 - Jul 2001

  Quantitative analysis of gene expression level by real time PCR. Validation of a bibliometric's tools applied to the Transcriptome.