Experience

Suny Upstate Medical Univ

• United States
• Law Enforcement
• 1 - 100 Employee

• Dental Resident

  • Jul 2017 - Present



University at Buffalo School of Dental Medicine

• United States
• Education Management
• 1 - 100 Employee

• Legislative Liaison

  • Jun 2014 - Present

  University at Buffalo School of Dental Medicine's Legislative Liaison and Ambassador for political issues and advocacy that pertain to dentistry and oral health care. Work in partnership with American Student Dental Association (ASDA) and District 2.



Cleveland Clinic Lerner Research Institute

• United States
• Research Services
• 100 - 200 Employee

• Department of Cellular and Molecular Medicine Research Student

  • May 2012 - May 2013

  The chemokine tumor necrosis factor (TNF) initiates the expression of genes involved in the recruitment and adhesion of leukocytes to sites of inflammation. Previous work demonstrates that protein arginine methyltransferase 5 (PRMT5), an enzyme that methylates protein-incorporated arginine residues, has roles in inflammatory gene expression. We demonstrate here that PRMT5 regulates the transcriptional induction of chemokine CXCL10, a secreted factor that functions primarily as a chemoattractant… The chemokine tumor necrosis factor (TNF) initiates the expression of genes involved in the recruitment and adhesion of leukocytes to sites of inflammation. Previous work demonstrates that protein arginine methyltransferase 5 (PRMT5), an enzyme that methylates protein-incorporated arginine residues, has roles in inflammatory gene expression. We demonstrate here that PRMT5 regulates the transcriptional induction of chemokine CXCL10, a secreted factor that functions primarily as a chemoattractant for pro-inflammatory T-cell populations. To elucidate how PRMT5 induces CXCL10, transcription factors were immunoprecipitated known to be involved in its expression. This determined that the p65 subunit of the NF-kB transcription factor contains the methylated arginine posttranslational modification catalyzed by PRMT5. This modification is not detected when PRMT5 is removed via RNA interference. We are developing site-directed mutations where the modified arginine residues are replaced with other amino acids to test the importance of these residues in the PRMT5-mediated transcriptional induction of CXCL10. Show more Show less



John Carroll University

• United States
• Higher Education
• 700 & Above Employee

• Teaching Assistant

  • Aug 2010 - May 2013

  Mentored, advised and worked alongside undergraduate chemistry students to properly train and equip them with the necessary and basic chemistry techniques in order to properly perform and carry out an experiment. Additionally, was in charge of ethically and confidentially grading set lab reports every week.