Tim D. Smith

Senior Software Engineer at AbCellera
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
Vancouver, British Columbia, Canada, CA
Languages
  • English -
  • Japanese -

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

5.0

/5.0
/ Based on 2 ratings
  • (2)
  • (0)
  • (0)
  • (0)
  • (0)

Filter reviews by:

Dylan Gunn

I had the pleasure of working with Tim for one and a half years at Boreal Genomics. Tim was instrumental in helping our engineering team to test and debug a huge range of issues in the development of a new instrument. He excelled at discovering, tracking and assisting in the diagnosis and resolution of a number of tricky software, firmware and hardware problems and our development would have been much slower without his keen attention to detail and his strong analytical and hands-on skills.

Parisa Zamiri

Tim joined Arsenal Medical initially as an intern for 6 months, but his contract was extended for an additional year. Tim developed automated fluorescent microscopic processes that have save the company both time and money. During his time I was immensely impressed with his enthusiasm for the projects, his innovative approach to problem solving, his dedication to the task and his ability to work effectively as a team member. He is a very accomplished young man and often surprised me with the depth and breadth of scientific knowledge, as well as, all things Japanese. Tim is a delight to work with and will be successful in any venture he takes on.

You need to have a working account to view this content.
You need to have a working account to view this content.

Experience

    • Canada
    • Biotechnology Research
    • 400 - 500 Employee
    • Senior Software Engineer
      • Jul 2021 - Present

      Jul 2021-Mar 2023: Software engineering, Data Architecture team Member of the core implementation team for an ELN integration effort spanning AbCellera's antibody production and characterization capabilities. Collaborated with scientists and automation engineers to deliver workflows to handle complex informatic, automation, and scientific processes. Delivered software platform capabilities to enable data scientists to achieve end-to-end scientific data capture. Mar 2023-present: Tech lead, Workflow Engineering Led a team of software developers delivering enabling informatic components for scientific workflows. Show less

    • United States
    • Software Development
    • 700 & Above Employee
    • Staff Data Scientist
      • Mar 2020 - Jul 2021

      As the data science experimentation lead, I drive analysis requirements for a cross-functional experimentation engineering program and lead development of automated experiment analysis solutions.

    • Senior Data Scientist
      • Apr 2018 - Mar 2020

      As a member of Mozilla's Product Data Science team, I help product managers and engineers implement, interpret, and experiment with Firefox telemetry.

    • Canada
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Research Engineer
      • Apr 2017 - Dec 2017

      • Led engineering efforts for multiplex panel design for Boreal’s Pro-Seq sequencing sample prep platform. Leveraged technologies including Python, R, scikit-learn random forest classifiers, SAT solvers, and Google Compute Cloud • Invented a pipeline for on-demand design of mutually compatible primer sequences for up to 50 loci in a single reaction, advancing Pro-Seq from a research tool towards marketable applications in personalized cancer monitoring from cell-free DNA in blood plasma. The panels give minimal yield of unwanted primer-dimer products despite a requirement for high-fidelity polymerases prone to primer-dimer amplification • Implemented methods for extracting primer-dimer product sequences from Illumina MiSeq reads of large multiplex panels, determining the contributing primers, and training a ML model to recognize incompatible oligos • Conducted and supported wet-lab experiments to optimize thermocycling conditions for Pro-Seq Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • NSF Graduate Research Fellow
      • Sep 2011 - Mar 2017

      Matrix engineering • Constructed 3D collagen and synthetic peptide matrices for macrophage encapsulation, measured material properties, assessed matrix structure with second-harmonic imaging, and quantified cell responses with ELISA and RT-qPCR Cellular immunobiology • Designed primers and implemented qPCR and microarray gene expression assays for macrophage polarization • Assessed the impact of conflicting inflammatory and anti-inflammatory cytokine signals on macrophage response using flow cytometry, ELISA, and multiplex ELISA assays Technology integration • Developed Python tools for quantitative analysis of GB-scale microscopy mosaics to measure cytokine secretion from individual macrophages exposed to different extracellular matrices • Implemented and validated pipelines in Python and R to describe cell migration from time-lapse microscopy imaging Advised by Dr. Wendy Liu, also formerly of Arsenal Medical. Research efforts in the Liu lab are focused on novel approaches for biomaterials that minimize the foreign body response. PhD awarded in March 2017. NSF GRFP fellow, 2013-2016. Show less

    • Canada
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Engineer
      • Jan 2010 - Aug 2011

      Applications engineering for the Boreal Genomics Aurora nucleic acid purification platform, which uses a novel electrophoretic technology to concentrate DNA and reject contaminants. Areas of particular focus include environmental and clinical samples. Skills emphasized include experimental design and analysis and quantitative PCR. Hired on recommendation of manager at Arsenal Medical. Applications engineering for the Boreal Genomics Aurora nucleic acid purification platform, which uses a novel electrophoretic technology to concentrate DNA and reject contaminants. Areas of particular focus include environmental and clinical samples. Skills emphasized include experimental design and analysis and quantitative PCR. Hired on recommendation of manager at Arsenal Medical.

  • Arsenal Medical
    • Watertown, Massachusetts
    • Biology Intern
      • Jun 2008 - May 2009

      Formerly WMR Biomedical; parent of 480 Biomedical. Employed as a full-time intern through the summer and stayed on part-time during school year. Implemented a cell-based immunofluorescence assay to evaluate material biocompatibility at a medical device startup. Designed data analysis programs to interpret and report results from cell-based assays and histology images. Independently developed automation tools for fluorescence and H&E microscopy image capture and analysis. Formerly WMR Biomedical; parent of 480 Biomedical. Employed as a full-time intern through the summer and stayed on part-time during school year. Implemented a cell-based immunofluorescence assay to evaluate material biocompatibility at a medical device startup. Designed data analysis programs to interpret and report results from cell-based assays and histology images. Independently developed automation tools for fluorescence and H&E microscopy image capture and analysis.

Education

  • Franklin W. Olin College of Engineering
    Bachelor of Science (BS), Engineering: Bioengineering
    2005 - 2010
  • UC Irvine
    PhD, Biomedical Engineering
    2011 - 2017
  • Thomas Jefferson High School for Science and Technology
    TJHSST Diploma
    2001 - 2005

Community

You need to have a working account to view this content. Click here to join now