Experience

Hepion Pharmaceuticals

• United States
• Biotechnology Research
• 1 - 100 Employee

• Director, Chemistry and Manufacturing

  • Sep 2021 - Present



Athenex

• United States
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Project Manager, CMC

  • Oct 2018 - Sep 2021



Spero Therapeutics

• United States
• Biotechnology Research
• 1 - 100 Employee

• Principal Scientist

  • Sep 2015 - Oct 2018

  - Project lead for Discovery Chemistry in novel antibiotic platform programs. - Collaborative team leader, managing in-house and external CRO resources. https://sperotherapeutics.com - Project lead for Discovery Chemistry in novel antibiotic platform programs. - Collaborative team leader, managing in-house and external CRO resources. https://sperotherapeutics.com



Novartis Institutes for BioMedical Research (NIBR)

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Investigator III

  • Sep 2009 - Sep 2015

  - Lab head for Global Discovery Chemistry in the infectious diseases and cardiovascular and metabolism therapeutic areas - Design, synthesis, and evaluation of chemical entities for the treatment of various diseases and disorders, progessing to critical decision points, on tight timelines - Specific focus on structure-activity relationship development, pharmaco kinetic property optimization, 3- dimensional molecular modeling, in silico molecular property calculations, advanced toxicity evaluation, patent preparation, peptide synthesis on solid support, and the synthesis and analytical evaluation of polymeric drug delivery molecules - Served as chemistry lead for two exploratory medicinal chemistry projects (including leading a global team of CRO chemists) as well providing chemistry oversight for early-stage project development - Responsible for the direct management of three associate chemists -Member of the PhD recruiting/hiring committee, as well as campus move organization Show less



Northwestern University

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Research Fellow, Scheidt Lab

  • Mar 2007 - Sep 2009

  - Developed a successful synthetic route toward the synthesis of the macrolide exiguolide - Completed the total synthesis and structural revision of the marine natural product (+)-neopeltolide - Developed and instructed a graduate level class: Chemistry 418 Organometallic Concepts in Synthesis - Developed skills in the synthesis, purification, and characterization of complex natural products and intermediates - Gained experience in the utilization of advanced 2-D 1H NMR techniques - Mentored one graduate student for independent research Show less



University at Buffalo

• United States
• Higher Education
• 700 & Above Employee

• Teaching and Research Assistant, Chemler Lab

  • Jan 2002 - Mar 2007

  - Developed, optimized, and examined the scope of a new reaction for the aminohalogenation of olefins using Pd(II) catalysis - Pioneered a new reaction using Cu(II) to promote intramolecular diamination of olefins - Developed skills in the preparation, purification and characterization of organic compounds including catalysis, heterocycle synthesis, microwave-mediated reactions, preparative and analytical HPLC separation, and small molecule synthesis - Extensive experience in 1H NMR, 13C NMR, 2D NMR, IR, and optical rotation techniques - Proficient with chemistry software: Scifinder, Beilstein, ChemDraw - Mentored three undergraduate students for independent research - Instructed eight semesters of general and organic chemistry lab and recitation as a teaching assistant Show less