Experience

35Pharma

• Biotechnology Research
• 1 - 100 Employee

• Vice President of Manufacturing

  • Apr 2022 - Present

  Lead the Manufacturing department team and outsourced CDMO project designed for the development of HS135, a potent protein trap against life threatening pulmonary disease. We are preparing the continuous supply required for clinical trials. Lead the Manufacturing department team and outsourced CDMO project designed for the development of HS135, a potent protein trap against life threatening pulmonary disease. We are preparing the continuous supply required for clinical trials.



HyperMabs Inc.

• Canada
• Biotechnology Research
• 1 - 100 Employee

• Vice President of Manufacturing

  • Jan 2022 - Present

• Director Of Manufacturing

  • Sep 2020 - Dec 2021



Forbius

• United States
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Director Of Manufacturing

  • Aug 2018 - Aug 2020

  Organize and grow the Manufacturing department focused on developing processes and analytics in support of outsourced manufacturing. Ensure clinical supply and plan for commercial supply of antibody drug conjugates and immunomodulators compounds targeting life threatening diseases. Organize and grow the Manufacturing department focused on developing processes and analytics in support of outsourced manufacturing. Ensure clinical supply and plan for commercial supply of antibody drug conjugates and immunomodulators compounds targeting life threatening diseases.



ProMetic

• Montreal, Canada Area

• Director, Manufacturing Sciences

  • Nov 2016 - Aug 2018

  I develop and manage a Department responsible for human plasma protein purification process scale-up, technology transfer to manufacturing facilities and process validation for regulatory submissions. I develop and manage a Department responsible for human plasma protein purification process scale-up, technology transfer to manufacturing facilities and process validation for regulatory submissions.



National Research Council Canada / Conseil national de recherches Canada

• Canada
• Research Services
• 700 & Above Employee

• Section Head, Purification

  • Feb 2016 - Nov 2016

  I was responsible of the management of three purification and glyco-engineering teams with up to 25 reports. Designing and executing client and internal innovation projects. Main achievements: Automation of platform purification processes for mg to gram range quantities, significantly improving productivity and output to industrial partners. The development of genuine scalable purification processes for various clients.

• Team Leader - Research Officer

  • Jan 2014 - Feb 2016

  I was responsible for managing a team of skilled professionals focussed on Biologics purification process development and operations; Process Analytics and protein characterization.



Héma-Québec

• Canada
• Hospitals and Health Care
• 700 & Above Employee

• Project Manager, Cell Production

  • May 2013 - Dec 2013



Available for new career opportunities

• Montréal

• Management of Protein Production, Process and Analytical Development

  • Jan 2013 - Apr 2013



Alexion Pharmaceuticals, Inc.

• United States
• Biotechnology Research
• 700 & Above Employee

• Director, Process Development

  • Feb 2012 - Dec 2012

  I was responsible for leading the local laboratory operations and transferring all process know-how and documentation related to the manufacturing, testing and characterization of asfotase alfa. I was responsible for leading the local laboratory operations and transferring all process know-how and documentation related to the manufacturing, testing and characterization of asfotase alfa.



Enobia Pharma

• Canada
• Biotechnology Research
• 1 - 100 Employee

• Director, Process Development

  • Jan 2010 - Feb 2012

  I overviewed outsourced manufacturing, protein product characterization and analytical assays validation for asfotase alfa an Fc-fusion protein. I lead the team responsible for all CMC activities transferred from the 2,000 liter scale cGMP manufacturer to the 20,000 liter scale manufacturer. During that period, I continued to manage the process development and analytical laboratory teams. The process development team was frequently required to troubleshoot process issues generated from the scale up at 20,000 liter. Show less

• Associate Director, Process Development

  • Aug 2008 - Dec 2009

  I was responsible for leading the clone identification process development and analytical development teams responsible for the production and characterization of Fc-fusion protein drugs. I was also responsible for the technical transfer to a larger contract manufacturing organization and overviewed small scale and the 400 L pilot runs. I concurrently overviewed manufacturing at the 2,000 L scale and contracted characterization work at external analytical laboratories.



Enobia Pharma

• Group Leader

  • Jan 2005 - Jul 2008

  I lead the R&D laboratories activities, including CHO cell clone preparation and isolation, bio-analytical assays development and transfer to GLP laboratories. I was also responsible for the design and the internal production of recombinant protein drug candidates. I concurrently developed with a contract manufacturing organization operating at the 2,000 L a protein production process for asfotase alfa. The quality control assay were developed in collaboration and qualified with the same CMO. I overviewed the manufacturing of asfotase alfa at the 2,000 L scale. Show less



BioMep

• Senior Biochemist

  • Apr 2001 - Dec 2004

  I lead a team of 7 research scientists for the development and production of candidate protein drug. Our team produced several targeted and fusion recombinant proteins, developed several functional assays. I lead a team of 7 research scientists for the development and production of candidate protein drug. Our team produced several targeted and fusion recombinant proteins, developed several functional assays.



Merck

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Industrial post-doctoral fellow

  • Jan 2000 - Apr 2001

  Molecular mechanism of caspase-3 activation Molecular mechanism of caspase-3 activation



CNRS

• Gif-sur-Yvette, France

• Post-Doctoral Fellow

  • Sep 1997 - Sep 1999

  Actin-based cellular motility mechanisms Actin-based cellular motility mechanisms