Thomas Di Mattia

Biology scientist at Volumina Medical
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Contact Information
us****@****om
(386) 825-5501
Location
Saint-Julien-en-Genevois, Auvergne-Rhône-Alpes, France, FR
Languages
  • Français Native or bilingual proficiency
  • Anglais Professional working proficiency

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Credentials

  • French habilitation to animal experimentation, Level 1
    -
  • Swiss habilitation to animal experimentation, LTK1
    Ecole polytechnique fédérale de Lausanne

Experience

    • Switzerland
    • Medical Equipment Manufacturing
    • 1 - 100 Employee
    • Biology scientist
      • Oct 2021 - Present

    • Switzerland
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Scientist
      • Oct 2021 - Present

    • Switzerland
    • Research Services
    • 700 & Above Employee
    • Postdoctoral Scientist
      • Aug 2020 - Sep 2021

      I led and managed a research project on the functional characterization of tight junction proteins and their link to actomyosin cytoskeleton. Main responsabilities: - Manage and organize scientific projects - Optimize, implement and perfom experiments, critically analyze and interpret the results - Document experiments in laboratory notebooks - Keeping abreast of the scientific literature - Supervision of a Master Student - Wrote and co-wrote scientific documents and articles - Communicate and promote the results (internal seminars) - Teaching activities: Teaching activity in life science (Fundamental Biology [22 hours] and Histology [22 hours]) at the University of Geneva (for undergraduate students; 2020-Now). Training: -Cell biology: culture of polarized epithelial cell lines, transwell assay, transient transfection, immunofluorescence -Molecular biology: cloning, PCR -Biochemistry: production and purification of recombinant proteins, Pull-Down, protein extraction, Western Blot -Imaging: ultrastructure expansion microscopy, super-resolution microscopy STED, confocal/Spinning Disk microscopy, live cell imaging, image processing, ImageJ/Fiji Macro Programming Show less

    • Research Services
    • 200 - 300 Employee
    • PHD Candidate
      • Oct 2015 - Mar 2020

      I led and managed a research project on the identification and functional characterization of a protein overexpressed in breast cancer, the protein MOSPD2. My main mission has been to decipher the physiological function of this protein; an essential notion to better understand the involvement of MOSPD2 in cancer. To sum up, I have shown that MOSPD2 is a critical protein that regulates the organelle dynamics within the cell. Main responsabilities: - Manage and organize scientific projects - Optimize, implement and perfom experiments, critically analyze and interpret the results - Document experiments in laboratory notebooks - Keeping abreast of the scientific literature - Supervision of undergraduate (1) and graduate (3) students - Wrote and obtained a grant proposal (Fondation pour la Recherche Médicale), wrote and co-wrote scientific documents and articles - Communicate and promote the results - I did oral presentations in national and international seminars such as Club Endocytose-Exocytose (Nice, France - 2019), 19th Regional Scientific Day of the Ligue Contre le Cancer (Illkirch, France - 2018), Club Endocytose-Exocytose (Barcelona, Spain - 2018). - Teaching activities: Courses at the Medical School of Strasbourg (for graduate students; 2 hours in 2016/2017/2018) / Teaching activity in life science (Biodiversity [44 hours] and Developmental Biology [22 hours]) at the University of Strasbourg (for undergraduate students; 2016-2017). Training: - Cell biology: culture of different cell lines, transient transfection, work in BSL2 laboratory, immunofluorescence - Molecular biology: cloning, PCR - Biochemistry: production and purification of recombinant proteins (Akta systems), purification of antibodies, Western Blot, Pull-Down - Imaging: confocal microscopy, super-resolution microscopy STED, live cell imaging, EM, ImageJ/Fiji Macro Programming - In vivo: subcutaneous injections of cancer cells in mice, bioluminescence imaging in living mice, histology Show less

    • France
    • Higher Education
    • 1 - 100 Employee
    • Member of a student association
      • Oct 2015 - Oct 2017

      As a team, we organized and managed "get together" events with the aim of promoting networking. As a team, we organized and managed "get together" events with the aim of promoting networking.

    • Research Services
    • 200 - 300 Employee
    • Engineer Assistant
      • Sep 2014 - Jun 2015

      I managed a research project that highlighted the subcellular localization of different lipid transport proteins. Main responsabilities: - Organizing my master project - Perform experiments, critically analyse and interpret the results - Document experiments in laboratory notebooks - Keeping abreast of the scientific literature - Promoting the results through report writing and oral presentations Training: cell biology (cell culture), immunofluorescence assay, molecular biology (cloning), biochemistry (protein extraction, Western Blot). Ph.D research grant from the French government; passed the doctoral school competition (Doctoral School of Life and Health Sciences, ED414, Strasbourg). Show less

    • Research Services
    • 200 - 300 Employee
    • Engineer Assistant
      • Jan 2014 - Feb 2014

      I studied the implication of the protein PDIP-1 in RNA metabolism. Training: molecular biology (cloning), biochemistry (production and purification of recombinant proteins, in vitro RNA degradation assay). I studied the implication of the protein PDIP-1 in RNA metabolism. Training: molecular biology (cloning), biochemistry (production and purification of recombinant proteins, in vitro RNA degradation assay).

Education

  • Université de Strasbourg
    PhD, Molecular and cellular Biology, With Honours
    2015 - 2019
  • Université de Strasbourg
    Master's degree, Developmental Biology and Stem Cells
    2013 - 2015
  • Université de Strasbourg
    Bachelor of Science, Cellular and Molecular Biology, Biochemistry and Physiology, With Honours
    2012 - 2013
  • Preparatory School, Biology Chemistry and Physics of Strasbourg
    2010 - 2012

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