Experience

University Medical Center Mainz

• Germany
• Hospitals and Health Care
• 700 & Above Employee

• Junior Professor for Mass Spectrometry-based Metabolomics

  • Aug 2022 - Present



University of Oxford

• United Kingdom
• Research Services
• 700 & Above Employee

• Academic Visitor

  • Jul 2022 - Present

• Senior Postdoctoral Research Scientist

  • Dec 2019 - Jun 2022

  Antigen Discovery GroupIndustry-funded position managed by a biotechnology company focusing on antigen discovery and immunotherapy



Dr. Margarete-Fischer-Bosch Institute of Clinical Pharmacology

• Stuttgart Area, Germany

• Wissenschaftlicher Mitarbeiter

  • Jan 2019 - Nov 2019

  • Establishment of a single-platform multi-OMICS workflow for the analysis of human tissue in the clinics • Patient specific characterization of cholestatic liver disease to generate molecular OMICS-networks • Major techniques: untargeted metabolomics, fresh frozen tissue, multi-OMICS • Establishment of a single-platform multi-OMICS workflow for the analysis of human tissue in the clinics • Patient specific characterization of cholestatic liver disease to generate molecular OMICS-networks • Major techniques: untargeted metabolomics, fresh frozen tissue, multi-OMICS



Utrecht University

• Netherlands
• Higher Education
• 700 & Above Employee

• Postdoctoral Researcher

  • Jun 2018 - Nov 2018

• PhD Candidate

  • Nov 2013 - Jun 2018

  Principal Investigator: Dr. Maarten Altelaar and Prof. Albert Heck• Development of a LC-MS based method for a systematic screening of kinase activities based on conserved activation sites (commercialized as QuantaKinome™ by Pepscope - patent pending)• Detection of a potential biomarkers for first line drug resistance in melanoma• Establishment of DIA workflows incorporating EThcD fragmentation, allowing the use of decision-tree-based spectral libraries for targeted data extraction• Collaborations with research groups focusing on neurobiology, antibody research and histone modifications leading to novel assays currently employed in obesity research and epigenetics• Targeted quantification of phosphorylated peptides and neuropeptides by LC-MS including SRM, PRM, data-independent acquisition, MRM cubed• Various steps in workflow automation for phosphopeptide enrichment by a liquid handling platform to facilitate high-throughput applications• Major techniques: phosphoproteomics sample preparation from various sample types, neuropeptide extraction from hypothalamus samples, membrane protein enrichment, nano-LC-MS (DDA, DIA, SRM, PRM) Show less



Caltech

• United States
• Research Services
• 700 & Above Employee

• Internship

  • Jul 2012 - Sep 2012



University of Basel

• Switzerland
• Research Services
• 700 & Above Employee

• Hilfswissenschaftler

  • 2006 - 2007

  Irregular involvement as research assistant in the lab of Prof. Martin Spiess, Biozentrum of the University of Basel in parallel to my high school education. Main research focus: Elucidation of the topology of mutated yeast Sec61 translocon variants Major techniques: site-directed mutagenesis, biotin-maleimide crosslinking, western blot analysis Irregular involvement as research assistant in the lab of Prof. Martin Spiess, Biozentrum of the University of Basel in parallel to my high school education. Main research focus: Elucidation of the topology of mutated yeast Sec61 translocon variants Major techniques: site-directed mutagenesis, biotin-maleimide crosslinking, western blot analysis