Experience

State University of New York Cortland

• United States
• Higher Education
• 700 & Above Employee

• Professor

  • Sep 2017 - Present

  Paper published: Curtis T.M., Hannett J.M., Harman R.M., Puoplo N.A. & Van de Walle G.R. 2018. The secretome of adipose-derived mesenchymal stem cells protects SH-SY5Y cells from arsenic-induced toxicity, independent of a neuron-like differentiation mechanism. Neurotoxicology 67, 54–64. Subaward contract from Nanohmics Inc. to examine additional cell lines in ECIS system for chemical toxicant detection, Sept 2018-March 2020, 52,250. STTR (Small Business Technology Transfer… Show more Paper published: Curtis T.M., Hannett J.M., Harman R.M., Puoplo N.A. & Van de Walle G.R. 2018. The secretome of adipose-derived mesenchymal stem cells protects SH-SY5Y cells from arsenic-induced toxicity, independent of a neuron-like differentiation mechanism. Neurotoxicology 67, 54–64. Subaward contract from Nanohmics Inc. to examine additional cell lines in ECIS system for chemical toxicant detection, Sept 2018-March 2020, 52,250. STTR (Small Business Technology Transfer Program) Phase I award with Jan Biotech Inc., Hybrid Nano-Bio Electronic Odor Detector, Dec 2018-June 2019, 45,000. SBIR (Small Business Innovation Research) subaward contract from Nanohmics Inc., Novel Fluorescence Lysosomal Yeast (FLY) Portable Biosensor for General Toxicity Testing, July 2019-Jan 2020, 42,000.

• Associate Professor

  • May 2012 - Aug 2017

  Courses frequently taught to undergraduate and graduate students: Human Physiology, Anatomy and Physiology, Biomedical Senior Seminar. Also served as college’s Pre-Medical/Dental Advisor. Principal investigator on grant to U.S. Army Center for Environmental Health Research to evaluate additional vertebrate cell lines for chemical sensitivity, temperature tolerance, and shelf life, 2011-2012, 77,000. Subcontractor on grant to U.S. Army Corps of Engineers Phase I and II SBIR… Show more Courses frequently taught to undergraduate and graduate students: Human Physiology, Anatomy and Physiology, Biomedical Senior Seminar. Also served as college’s Pre-Medical/Dental Advisor. Principal investigator on grant to U.S. Army Center for Environmental Health Research to evaluate additional vertebrate cell lines for chemical sensitivity, temperature tolerance, and shelf life, 2011-2012, 77,000. Subcontractor on grant to U.S. Army Corps of Engineers Phase I and II SBIR (Butler-PI) to evaluate encapsulation technology for increased environmental stability of vertebrate cells, 2013-2016, 275,000. Team member on SUNY Health Now Grant (Travis-PI; collaboration between 5 SUNY institutions) to develop hand-held biosensors for rapid diagnosis and study of neural disease and neurotoxins, 2014-2015, $10,000. Papers published: Pennington M.R., Curtis T.M., Divers T.J., Wagner B., Ness S.L., Tennant B.C., Van de Walle G.R. 2016. Equine Mesenchymal Stromal Cells from Different Sources Efficiently Differentiate into Hepatocyte-Like Cells. Tissue Eng Part C Methods. Jun 22(6):596-607. Harman R.M., Curtis T.M., Argyle D.J., Coonrod S.A., Van de Walle G.R. 2016. A Comparative Study on the In Vitro Effects of the DNA Methyltransferase Inhibitor 5-Azacytidine (5-AzaC) in Breast/Mammary Cancer of Different Mammalian Species. J Mammary Gland Biol Neoplasia. Jun 21(1-2):51-66. Bussche L., Harman R.M., Syracuse B.A., Plante E.L., Lu Y.C., Curtis T.M., Ma M., Van de Walle G.R. 2015. Microencapsulated equine mesenchymal stromal cells promote cutaneous wound healing in vitro. Stem Cell Research and Therapy. Apr 11;6(1):66. Curtis, T.M., Thorn, T., Collins, A.M., Brennan, L.M., Widder, M.W., van der Schalie W.H., Vo, N.T.K., and Bols, N.C. 2013 Suitability of Invertebrate and Vertebrate Cells in a Portable Impedance-based Toxicity Sensor: Temperature Mediated Impacts on Long-Term Survival. Toxicology In Vitro 27, 2061-2066. * Undergraduate students



State University of New York Cortland

• United States
• Higher Education
• 700 & Above Employee

• Assistant Professor

  • 2007 - 2012

  Courses frequently taught to undergraduate and graduate students: Human Physiology (BIO 514), Anatomy and Physiology (BIO 301/302), Biomedical Senior Seminar (BMS 460). Also served as college’s Pre-Medical/Dental Advisor. Principal investigator on grant to U.S. Army Center for Environmental Health Research to examine additional cell lines in ECIS system for chemical toxicant detection, 2008-2010, 85,000. Papers published: Curtis, T.M., Widder, M.W., Brennan, L.M., Schwager… Show more Courses frequently taught to undergraduate and graduate students: Human Physiology (BIO 514), Anatomy and Physiology (BIO 301/302), Biomedical Senior Seminar (BMS 460). Also served as college’s Pre-Medical/Dental Advisor. Principal investigator on grant to U.S. Army Center for Environmental Health Research to examine additional cell lines in ECIS system for chemical toxicant detection, 2008-2010, 85,000. Papers published: Curtis, T.M., Widder, M.W., Brennan, L.M., Schwager, S.J., van der Schalie, W.H., Fey, J., Salazar, N. 2009. A portable cell based impedance sensor for toxicity monitoring in drinking water. Lab Chip 9:2176-2183. Curtis, T.M., Tabb, J., Romeo, L., Schwager, S.J., Widder, M.W., van der Schalie, W.H. 2009. Improved cell sensitivity and longevity in a rapid impedance-based toxicity sensor. J. Appl. Toxicol. 29(5):374-380. Curtis, T.M., Naal, R.M., Batt, C., Tabb, J., Holowka, D. 2008. Development of a mast cell-based biosensor. Biosens. Bioelectron. 23(7):1024-1031. Show less Courses frequently taught to undergraduate and graduate students: Human Physiology (BIO 514), Anatomy and Physiology (BIO 301/302), Biomedical Senior Seminar (BMS 460). Also served as college’s Pre-Medical/Dental Advisor. Principal investigator on grant to U.S. Army Center for Environmental Health Research to examine additional cell lines in ECIS system for chemical toxicant detection, 2008-2010, 85,000. Papers published: Curtis, T.M., Widder, M.W., Brennan, L.M., Schwager… Show more Courses frequently taught to undergraduate and graduate students: Human Physiology (BIO 514), Anatomy and Physiology (BIO 301/302), Biomedical Senior Seminar (BMS 460). Also served as college’s Pre-Medical/Dental Advisor. Principal investigator on grant to U.S. Army Center for Environmental Health Research to examine additional cell lines in ECIS system for chemical toxicant detection, 2008-2010, 85,000. Papers published: Curtis, T.M., Widder, M.W., Brennan, L.M., Schwager, S.J., van der Schalie, W.H., Fey, J., Salazar, N. 2009. A portable cell based impedance sensor for toxicity monitoring in drinking water. Lab Chip 9:2176-2183. Curtis, T.M., Tabb, J., Romeo, L., Schwager, S.J., Widder, M.W., van der Schalie, W.H. 2009. Improved cell sensitivity and longevity in a rapid impedance-based toxicity sensor. J. Appl. Toxicol. 29(5):374-380. Curtis, T.M., Naal, R.M., Batt, C., Tabb, J., Holowka, D. 2008. Development of a mast cell-based biosensor. Biosens. Bioelectron. 23(7):1024-1031. Show less



Agave BioSystems

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist

  • Sep 2004 - Jul 2007

  Research resulted in the development of a novel chemical and biological toxicant sensor using mammalian cells. The development of the sensor involved screening cell lines for optimal toxicity, fabrication of cell cartridge and maintenance system, and the development of data analysis software. Specific achievements involve: •Principal investigator on Small Business Innovation Research (SBIR) to develop a respiratory endothelial cell sensor for real-time air toxicity monitoring (Phase I… Show more Research resulted in the development of a novel chemical and biological toxicant sensor using mammalian cells. The development of the sensor involved screening cell lines for optimal toxicity, fabrication of cell cartridge and maintenance system, and the development of data analysis software. Specific achievements involve: •Principal investigator on Small Business Innovation Research (SBIR) to develop a respiratory endothelial cell sensor for real-time air toxicity monitoring (Phase I and II, U.S. Army Center for Environmental Health Research). •Principal investigator on Small Business Technology Transfer Program (STTR) to develop a portable cell maintenance system (Phase I and II, U.S. Army Center for Environmental Health Research). •Procured over 500,000 dollars in commercial funding to further develop cell sensor. •Frequently gave presentations and conducted lab demonstrations for potential investors, partners, and Army sponsors. •Developed and maintained several collaborations with outside companies and various academic groups. •Established and managed the cell sensor development team which included four engineers, four Ph.D./M.S. scientists, and two technicians.

• Staff Scientist

  • Sep 2001 - Aug 2004

  Research focused on the development of novel cell based and antibody based assays for the detection of pathogens. Specific achievements involve: •Developed a novel fluorogenic mast cell-based biosensor for microbial monitoring (Curtis et al., Biosensors and Bioelectronics 2007). •Principal investigator on SBIR grant to develop a high-throughput wound healing assay to screen drugs (US Army Research Office). •Principal investigator on SBIR grant to develop a dipstick assay for… Show more Research focused on the development of novel cell based and antibody based assays for the detection of pathogens. Specific achievements involve: •Developed a novel fluorogenic mast cell-based biosensor for microbial monitoring (Curtis et al., Biosensors and Bioelectronics 2007). •Principal investigator on SBIR grant to develop a high-throughput wound healing assay to screen drugs (US Army Research Office). •Principal investigator on SBIR grant to develop a dipstick assay for field detection of Leishmania parasites using quantum dots (Walter Reed Army Institute of Research). •Established and managed assay development team which included one engineer, two M.S. scientists, and two technicians. •Participated in the design and equipment procurement of a dedicated cell culture and microscopy facility.