Manager, Mass Spectrometry and Proteomics

• Aug 2022 - Present

Proteomics Consultant

• Jan 2021 - Jul 2022

Research Associate, Mass Spectrometry

• 2018 - Present

Lead proteomics and protein characterization projects to support drug candidate nomination and early preclinical drug development activities.• DMPK: established, planned, and conducted ADME assays including in vivo and in vitro PK assays and Met-ID.• Interpret preclinical pharmacokinetic data to inform the design of preclinical pharmacology.• Protein characterization and identification (intact protein assay, peptide mapping, post-translation modification), MS-based proteomics, protein target ID (DARTS, IP), and binding residues determination (covalent ligands).• Developed and validated LC-MS/MS (UPLC-QTof) methods and sample preparation methods (SPE, SEC, PPT, IEX) for quantification/identification of small molecules and proteins.• Wrote SOPs, assay protocols, method development / validation reports, and analysis reports.

Course Instructor

• 2017 - 2019

• Course instructor for “Separations, Chromatography, and Microfluidics (CHM 416)” in Winter 2017 and winter 2018. Revised and delivered lectures; designed course activities including group presentations, term papers, and group discussions; Developed and evaluated assignments and examinations. • Developed a Raman spectroscopy module for “Instrumentation Laboratory II, CHM 397”.• Guest instructor for "Advanced Interdisciplinary Research Laboratory, JCB 487"• Guest lecturer for "Advanced Topics in Analytical Chemistry, CHM 414"

Postdoctoral Researcher / Bioanalytical Chemistry

• 2015 - 2018

• Coordinated a team of researchers in a joint industrial/academic project resulted in successful development of a platform for the industrial-scale production of conjugated biomaterials.• Conducted method development/validation for quantification and characterization of drugs and organic compounds using HPLC (Agilent 1100), LC-MS/MS (Sciex QStarXL & API 4000), ICP-OES, FT-IR, and UV-VIS.• Partnered with group leadership to advise on and set research strategy, and define success criteria for the projects• Assisted team members in the experimental design and data analysis, provided training sessions, presented findings to the team and prepared progress reports for the team leadership.• Mentored several graduate and undergraduate students; provided advice on study designs, analytical planning, project updates, and milestones.• Performed inventory control and communication with vendors, monthly lab safety inspection, and lab instruments operation and maintenance.

Research Assistant / Bioanalytical Chemistry

• 2011 - 2015

• Developed microchip-based biosensors for detection of nucleic acid cancer biomarkers resulting in 10 peer-reviewed papers and 1 patent. • Our research involved fabrication and surface treatment of polymeric chips, fluid control in microfluidic channels, optical imaging, ESI-MS characterization, as well as data analysis and validation. • Developed exceptional teamwork and communication skills through collaborated with Canadian and international researchers, presenting at several international conferences and writing in prestigious scientific journals. • Mentored several undergraduate students.

Mitacs Accelerate Intern

• 2013 - 2014

• Developed colorimetric test strips based on Colloidal crystals for differentiation of fuel mixtures. The product is patented and is on its way to commercialization. • managed joint meetings and periodic reports for industrial clients. • Conducted materials fabrication (Thin film deposition, Chemical vapor deposition, plasma treatment) particle size analysis (SEM, TEM, and DLS) and surface characterization techniques (contact angle and zeta potential measurements). • Developed colorimetric test strips based on Colloidal crystals for differentiation of fuel mixtures. The product is patented and is on its way to commercialization. • managed joint meetings and periodic reports for industrial clients. • Conducted materials fabrication (Thin film deposition, Chemical vapor deposition, plasma treatment) particle size analysis (SEM, TEM, and DLS) and surface characterization techniques (contact angle and zeta potential measurements).

Research Assistant

• Sep 2004 - May 2007

• Developed sample preparation (liquid-liquid microextraction) and detection (HPLC) methods for determination of various drugs (e.g. Tramadol, Fentanyl) in human specimens • Responsible for maintenance and troubleshooting of HPLC-UV and GC-FID instruments in the instrumentation lab. • Developed sample preparation (liquid-liquid microextraction) and detection (HPLC) methods for determination of various drugs (e.g. Tramadol, Fentanyl) in human specimens • Responsible for maintenance and troubleshooting of HPLC-UV and GC-FID instruments in the instrumentation lab.

Team Lead

• Feb 2006 - Apr 2007

- Coordinated a team of graduate students from chemistry, health sciences and professional safety departments for preparation of guidelines for proper safety and waste disposal practices in chemistry labs. The guidelines were later published as two separate books. - Coordinated a team of graduate students from chemistry, health sciences and professional safety departments for preparation of guidelines for proper safety and waste disposal practices in chemistry labs. The guidelines were later published as two separate books.