Experience

Institute for basic science (IBS)

• Government Administration
• 100 - 200 Employee

• Master Thesis

  • Sep 2023 - Present

  Daejeon, South Korea I am currently working on generating SCON (Short Conditional intrON) knock-in within the SOX2 gene of zebrafish using CRISPR-Cas9. This novel genetic construct behaves like an intron in its uninduced state but can prematurely terminate translation, specifically upon cre-based induction. Hence allowing us to generate scarless conditional knockout alleles in vivo. This approach could be very useful in studying developmentally important gene functions in the adult stage.



National Center for Cell Science

• India
• Biotechnology Research
• 1 - 100 Employee

• Summer Research Fellow

  • Jun 2023 - Aug 2023

  Pune, Maharashtra, India I worked under Dr. Jomon Joseph (Scientist G) at NCCS. During my time at NCCS, I was able to successfully clone GRP75 and validate its expression in a bacterial host. I also worked on the expression of PACS2 protein for in-house antibody generation in mice.



Birla Institute of Technology and Science, Pilani

• India
• Higher Education
• 700 & Above Employee

• Undergraduate Research Assistant

  • Sep 2022 - May 2023

  Pilani, Rajasthan, India • Worked under Prof. Syamantak Majumder on RNA methylation in TGF-Beta induced endothelial to mesenchymal transition. Our findings demonstrated that the induction of TGF-Beta indeed resulted in EMT, characterized by cellular changes. We observed no significant alterations in the overall RNA methylation levels. Additionally, the expression of the methyltransferase complex remained unchanged. • Worked under Prof. Meghana Tare on neurodegenerative diseases - performed climbing and lifespan… Show more • Worked under Prof. Syamantak Majumder on RNA methylation in TGF-Beta induced endothelial to mesenchymal transition. Our findings demonstrated that the induction of TGF-Beta indeed resulted in EMT, characterized by cellular changes. We observed no significant alterations in the overall RNA methylation levels. Additionally, the expression of the methyltransferase complex remained unchanged. • Worked under Prof. Meghana Tare on neurodegenerative diseases - performed climbing and lifespan assay on the Drosophila model of Parkinson's and Alzheimer's. Parkin RNAi males showed a 50% decline in climbing ability. Tau flies exhibited a gradual reduction in climbing ability, but the trend was not statistically significant. I also worked on a CRISPR strategy to create drosophila mutant model.

• Undergraduate Research Assistant

  • Jan 2022 - Sep 2022

  Pilani, Rajasthan, India • Worked under Dr. Balakumaran Chandrasekar on mechanism of action of plant chitinase in plant-pathogen interaction and role of chitin in plant immunity. • Worked under Dr. Syamantak Majumder to understand the role of non-coding RNA in Cardiovascular diseases.



Indian Institute of Science Education and Research (IISER), Pune

• India
• Research Services
• 700 & Above Employee

• Summer Research Intern

  • May 2022 - Jul 2022

  Pune, Maharashtra, India I standardized flight assay for the lab, wherein I was able to show that, wing defect in Drosophila P58S start to appear from the 3rd day onwards, learnt in-silico design of ssODN vectors to make point mutation, learnt DAM assay and rhythmically to analyse the DAM assay data.



Biological Sciences Association

• India
• E-Learning Providers
• 1 - 100 Employee

• Core Member and Scientific Content Writer

  • May 2021 - Jul 2022

  Pilani, Rajasthan, India • Written an article review on Quantum Biology • Hosted an interview talk with Dr. Meghana Tare on her research work