Steven Hepensteil

Intern - Enzyme Replacement Therapies at Regeneron
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Contact Information
us****@****om
(386) 825-5501
Location
Wilton Center, Connecticut, United States, US

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Bio

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Credentials

  • How to Be a Good Mentee and Mentor
    LinkedIn
    Jun, 2022
    - Nov, 2024

Experience

    • United States
    • Biotechnology
    • 700 & Above Employee
    • Intern - Enzyme Replacement Therapies
      • May 2023 - Present

      - Accelerated a pipeline project aiming to validate enzyme replacement gene therapies for lysosomal storage diseases. - Piloted the development of in vitro and in vivo experiments to confirm delivery across the blood brain barrier. - Conducted assays and analysis to determine plasmid expression while measuring biodistribution and enzymatic activity. - Accelerated a pipeline project aiming to validate enzyme replacement gene therapies for lysosomal storage diseases. - Piloted the development of in vitro and in vivo experiments to confirm delivery across the blood brain barrier. - Conducted assays and analysis to determine plasmid expression while measuring biodistribution and enzymatic activity.

  • The Hurley Lab
    • Rensselaer Polytechnic Institute (Troy, NY)
    • Undergraduate Research Assistant
      • Jul 2021 - Present

      - Investigated how protein complexes regulate RNA metabolism in the circadian clock. - Lead efforts to isolate RNA using in vivo RNA immunoprecipitation to determine RNA’s bound to circadian proteins. - Created ways to optimize the expression of several circadian proteins to facilitate downstream protein purification protocols. - Used SDS-PAGE and western blot analysis to qualitatively confirm proper protein pulldown and expression levels. - Investigated how protein complexes regulate RNA metabolism in the circadian clock. - Lead efforts to isolate RNA using in vivo RNA immunoprecipitation to determine RNA’s bound to circadian proteins. - Created ways to optimize the expression of several circadian proteins to facilitate downstream protein purification protocols. - Used SDS-PAGE and western blot analysis to qualitatively confirm proper protein pulldown and expression levels.

    • United States
    • Biotechnology
    • 700 & Above Employee
    • Intern - Research Program Management Operations
      • May 2022 - Aug 2022

      - Supported key projects in research and discovery through collaborating across many cross functional teams. - Created resources for research scientists to request and utilize human samples. - Managed data migration into a new system for tracking industry-academic collaborations. - Supported key projects in research and discovery through collaborating across many cross functional teams. - Created resources for research scientists to request and utilize human samples. - Managed data migration into a new system for tracking industry-academic collaborations.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Undergraduate Lab Mentor in Intro Cell/Molecular Biology
      • Jan 2022 - May 2022

      - Mentored underclassman students in proper safety and technical protocols while preparing lab reagents for use in class. - Mentored underclassman students in proper safety and technical protocols while preparing lab reagents for use in class.

  • Parlor Pizza and Wine Bar
    • Wilton Center, Connecticut, United States
    • Restaurant and Catering Cook
      • Feb 2020 - Aug 2021

      - Oversaw catering events of over 200 guests, managing cooks and waitstaff to carry out their tasks in a timely manner. - Executed a variety of complex dishes in the fast-paced and high-pressure environment of a professional gourmet kitchen. - Oversaw catering events of over 200 guests, managing cooks and waitstaff to carry out their tasks in a timely manner. - Executed a variety of complex dishes in the fast-paced and high-pressure environment of a professional gourmet kitchen.

  • The Pizza Truck Co
    • Bethel, Connecticut, United States
    • Manager
      • Mar 2018 - Sep 2020

Education

  • Rensselaer Polytechnic Institute
    Bachelor's degree, Biology, General
    2020 - 2024
  • Vermont Academy
    High School Diploma
    2017 - 2019
  • Wilton High School
    High School Diploma
    2014 - 2017

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