Steven Hepensteil
Intern - Enzyme Replacement Therapies at Regeneron- Claim this Profile
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Bio
Credentials
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How to Be a Good Mentee and Mentor
LinkedInJun, 2022- Nov, 2024
Experience
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Regeneron
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United States
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Biotechnology
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700 & Above Employee
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Intern - Enzyme Replacement Therapies
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May 2023 - Present
- Accelerated a pipeline project aiming to validate enzyme replacement gene therapies for lysosomal storage diseases. - Piloted the development of in vitro and in vivo experiments to confirm delivery across the blood brain barrier. - Conducted assays and analysis to determine plasmid expression while measuring biodistribution and enzymatic activity. - Accelerated a pipeline project aiming to validate enzyme replacement gene therapies for lysosomal storage diseases. - Piloted the development of in vitro and in vivo experiments to confirm delivery across the blood brain barrier. - Conducted assays and analysis to determine plasmid expression while measuring biodistribution and enzymatic activity.
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The Hurley Lab
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Rensselaer Polytechnic Institute (Troy, NY)
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Undergraduate Research Assistant
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Jul 2021 - Present
- Investigated how protein complexes regulate RNA metabolism in the circadian clock. - Lead efforts to isolate RNA using in vivo RNA immunoprecipitation to determine RNA’s bound to circadian proteins. - Created ways to optimize the expression of several circadian proteins to facilitate downstream protein purification protocols. - Used SDS-PAGE and western blot analysis to qualitatively confirm proper protein pulldown and expression levels. - Investigated how protein complexes regulate RNA metabolism in the circadian clock. - Lead efforts to isolate RNA using in vivo RNA immunoprecipitation to determine RNA’s bound to circadian proteins. - Created ways to optimize the expression of several circadian proteins to facilitate downstream protein purification protocols. - Used SDS-PAGE and western blot analysis to qualitatively confirm proper protein pulldown and expression levels.
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Regeneron
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United States
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Biotechnology
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700 & Above Employee
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Intern - Research Program Management Operations
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May 2022 - Aug 2022
- Supported key projects in research and discovery through collaborating across many cross functional teams. - Created resources for research scientists to request and utilize human samples. - Managed data migration into a new system for tracking industry-academic collaborations. - Supported key projects in research and discovery through collaborating across many cross functional teams. - Created resources for research scientists to request and utilize human samples. - Managed data migration into a new system for tracking industry-academic collaborations.
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Rensselaer Polytechnic Institute
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United States
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Higher Education
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700 & Above Employee
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Undergraduate Lab Mentor in Intro Cell/Molecular Biology
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Jan 2022 - May 2022
- Mentored underclassman students in proper safety and technical protocols while preparing lab reagents for use in class. - Mentored underclassman students in proper safety and technical protocols while preparing lab reagents for use in class.
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Parlor Pizza and Wine Bar
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Wilton Center, Connecticut, United States
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Restaurant and Catering Cook
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Feb 2020 - Aug 2021
- Oversaw catering events of over 200 guests, managing cooks and waitstaff to carry out their tasks in a timely manner. - Executed a variety of complex dishes in the fast-paced and high-pressure environment of a professional gourmet kitchen. - Oversaw catering events of over 200 guests, managing cooks and waitstaff to carry out their tasks in a timely manner. - Executed a variety of complex dishes in the fast-paced and high-pressure environment of a professional gourmet kitchen.
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The Pizza Truck Co
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Bethel, Connecticut, United States
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Manager
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Mar 2018 - Sep 2020
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Education
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Rensselaer Polytechnic Institute
Bachelor's degree, Biology, General -
Vermont Academy
High School Diploma -
Wilton High School
High School Diploma