Steven Bremmer
Principal Scientist at Oerth Bio- Claim this Profile
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Bio
Experience
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Oerth Bio
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United States
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Biotechnology Research
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1 - 100 Employee
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Principal Scientist
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Nov 2023 - Present
My role is to lead a team of talented scientists with the objective of measuring the effects of PROTACs on agriculturally relevant organisms. We are tasked with designing robust protein quantitation assays for specific targets across three Kingdoms of life.
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Senior Scientist
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Apr 2022 - Nov 2023
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BASF
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Germany
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Chemical Manufacturing
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700 & Above Employee
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Senior Scientist II
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Oct 2021 - Apr 2022
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Senior Scientist
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Dec 2016 - Oct 2021
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Scientist
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Oct 2012 - Dec 2016
I am currently a Scientist in the Metabolite and Protein Analytics group. We perform a full spectrum of protein characterization techniques to support the Plant Sciences project needs. These techniques include recombinant protein expression and purification, protein interaction analysis, quantitative assay development with immunoassay and MRM LC-MS techniques. We also provide protein engineering and enzyme assay services. In addition to my scientific roles, I also worked as the coordinator… Show more I am currently a Scientist in the Metabolite and Protein Analytics group. We perform a full spectrum of protein characterization techniques to support the Plant Sciences project needs. These techniques include recombinant protein expression and purification, protein interaction analysis, quantitative assay development with immunoassay and MRM LC-MS techniques. We also provide protein engineering and enzyme assay services. In addition to my scientific roles, I also worked as the coordinator for external seminars, founded and lead the Global Proteomic community at BASF and contribute to innovation facilitation as a member of the local innovation team.
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University of Michigan
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United States
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Higher Education
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700 & Above Employee
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Postdoctoral Fellow
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Dec 2009 - Sep 2012
Research conducted as a joint assignment with Matthew Soellner and Anne McNeil from the Departments of Pharmacy and Chemistry. My postdoctoral research was focused on developing peptide-like sensors for protease activity. I developed a novel artificial peptide sequence that responded to protease activity by transitioning a solution to a hydrogel. This work resulted in 2 publications. 1. Bremmer, S.C., Chen, J., McNeil, A.J., Soellner, M.B. (2012) A general method for… Show more Research conducted as a joint assignment with Matthew Soellner and Anne McNeil from the Departments of Pharmacy and Chemistry. My postdoctoral research was focused on developing peptide-like sensors for protease activity. I developed a novel artificial peptide sequence that responded to protease activity by transitioning a solution to a hydrogel. This work resulted in 2 publications. 1. Bremmer, S.C., Chen, J., McNeil, A.J., Soellner, M.B. (2012) A general method for detecting protease activity via gelation and its application to artificial clotting. Chem. Commun. 48, 5482-5484. 2. Bremmer, S.C., McNeil, A.J., Soellner, M.B. (2014) Enzyme-triggered gelation: targeting proteases with internal cleavage sites. Chem. Commun. 50, 1691-1693. Show less Research conducted as a joint assignment with Matthew Soellner and Anne McNeil from the Departments of Pharmacy and Chemistry. My postdoctoral research was focused on developing peptide-like sensors for protease activity. I developed a novel artificial peptide sequence that responded to protease activity by transitioning a solution to a hydrogel. This work resulted in 2 publications. 1. Bremmer, S.C., Chen, J., McNeil, A.J., Soellner, M.B. (2012) A general method for… Show more Research conducted as a joint assignment with Matthew Soellner and Anne McNeil from the Departments of Pharmacy and Chemistry. My postdoctoral research was focused on developing peptide-like sensors for protease activity. I developed a novel artificial peptide sequence that responded to protease activity by transitioning a solution to a hydrogel. This work resulted in 2 publications. 1. Bremmer, S.C., Chen, J., McNeil, A.J., Soellner, M.B. (2012) A general method for detecting protease activity via gelation and its application to artificial clotting. Chem. Commun. 48, 5482-5484. 2. Bremmer, S.C., McNeil, A.J., Soellner, M.B. (2014) Enzyme-triggered gelation: targeting proteases with internal cleavage sites. Chem. Commun. 50, 1691-1693. Show less
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Purdue University
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United States
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Higher Education
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700 & Above Employee
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Graduate Teaching Assistant
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Aug 2004 - May 2009
During my time at Purdue I funded my thesis research working as a graduate teaching assistant. Overall, I was responsible for hosting material review sessions, grading, and office hour help for 5 semesters of a 500 level biochemistry course as well as 2 semesters in medical school biochemistry. In addition, I also taught a semester of analytical biochemistry. My efforts were recognized by the university, earning an award for teaching excellence in biochemistry. During my time at Purdue I funded my thesis research working as a graduate teaching assistant. Overall, I was responsible for hosting material review sessions, grading, and office hour help for 5 semesters of a 500 level biochemistry course as well as 2 semesters in medical school biochemistry. In addition, I also taught a semester of analytical biochemistry. My efforts were recognized by the university, earning an award for teaching excellence in biochemistry.
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L Perrigo Co
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United States
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Laboratory Technician/ Trainer
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Sep 2001 - Sep 2003
During my employment my responsibilities included quality control testing of raw materials and finished products using USP methods and HPLC assays. After 1 year of employment I was promoted to lab trainer. My responsibilities included technical, stewardship, and safety training for developing fellow employees. During my employment my responsibilities included quality control testing of raw materials and finished products using USP methods and HPLC assays. After 1 year of employment I was promoted to lab trainer. My responsibilities included technical, stewardship, and safety training for developing fellow employees.
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Education
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Purdue University
Doctor of Philosophy (Ph.D.), Biochemistry -
Grand Valley State University
Bachelor of Science (B.S.), Biological and Biomedical Sciences -
Grand Rapids Community College
Associate of Arts (A.A.), Biology, General