Experience

Enterprise Therapeutics

• United Kingdom
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Head of Chemistry

  • Apr 2018 - Present

  University of Sussex



SPCR CONSULTING LIMITED

• United Kingdom
• Research
• 1 - 100 Employee

• Director

  • 2017 - Present

  London, United Kingdom



Respivert, Ltd.

• Pharmaceutical Manufacturing

• Head of Chemistry

  • Apr 2015 - 2017

  London, United Kingdom Responsible for discovery chemistry and pharmacokinetic activities at Respivert (a subsidiary of Janssen) including the initiation and management of new research projects. Key aspects include selection and appointment of CROs, consultants and university collaborations in support of new and ongoing programmes. Chemistry expert for clinical development programmes and new strategic alliance activities with accountability for the Respivert IP portfolio (>30 filed patent families).



SPCR Consulting Limited

• Consultant

  • Jul 2014 - Apr 2015

  South East of UK SPCR Consulting provides expertise in medicinal chemistry and drug discovery, including project initiation, flow chart design, lead optimisation, candidate selection, lead series reviews, candidate assessments and preclinical development.



Novartis

• Switzerland
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Director of Medicinal Chemistry

  • Dec 2012 - Jun 2014

  Horsham, UK Led a medicinal chemistry team of 36 chemists focused on discovering new chemical entities to target the respiratory diseases of cystic fibrosis, pulmonary fibrosis, asthma, COPD and pulmonary arterial hypertension. Member of the Respiratory Disease Board, responsible for approving candidate molecule development nominations and strategically directing a portfolio of projects through pre-clinical assessment to Phase I and PoC. Key member of the Portfolio Alignment Team, proactively seeking… Show more Led a medicinal chemistry team of 36 chemists focused on discovering new chemical entities to target the respiratory diseases of cystic fibrosis, pulmonary fibrosis, asthma, COPD and pulmonary arterial hypertension. Member of the Respiratory Disease Board, responsible for approving candidate molecule development nominations and strategically directing a portfolio of projects through pre-clinical assessment to Phase I and PoC. Key member of the Portfolio Alignment Team, proactively seeking alliance opportunities to complement the internal respiratory portfolio.

• Director Respiratory and Inhalation Chemistry

  • Apr 2007 - Nov 2012

  Horsham Director in the Global Discovery Chemistry group, with specific expertise and responsibility in inhalation drug discovery. Board member of the Respiratory Disease Therapeutic area. Member of the Chemistry Global Leadership team, Leader and initiator of drug discovery projects, cross therapeutic area reviewer of development candidate proposals.

• Investigator/Senior Investigator

  • 1998 - Mar 2007

  Horsham,West Sussex,UK Group leader and project team leader, led several successful respiratory lead optimisation projects.

• Investigator

  • Apr 1997 - Mar 1998

  Basel Area, Switzerland One year secondment to the Oncology Research team



Ciba-Geigy

• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Research scientist & team leader

  • Nov 1989 - Apr 1997

  Macclesfield, Cheshire , UK In 1989 I joined Ciba-Geigy as a Research Scientist, progessing to leading a team of chemists working in the antisense oligonucleotide area.



University of Oxford

• United Kingdom
• Research Services
• 700 & Above Employee

• Post Doc

  • Nov 1987 - Oct 1989

  Dyson Perrins Labs , Oxford