Suzanne Miedema
Postdoctoral Researcher iPSC models of FTD at CNCR, Center for Neurogenomics & Cognitive Research- Claim this Profile
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Nederlands Native or bilingual proficiency
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Engels Full professional proficiency
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Indonesisch Elementary proficiency
Topline Score
Bio
Jinte Middeldorp
I supervised Suzanne during a 6 month internship at Stanford University. She independently and successfully applied for funding to support her stay in Palo Alto. We worked well together, but she was also very capable of working independently, designing and performing experiments. She picks up new techniques really fast and was able to clearly present her work in English, both orally and in writing. I got to know Suzanne as an intelligent young woman, enthusiastic and knowledgable about molecular biology and neuroscience. She has a fun and open personality and is easily liked by others, a recommendation for any team.
Jinte Middeldorp
I supervised Suzanne during a 6 month internship at Stanford University. She independently and successfully applied for funding to support her stay in Palo Alto. We worked well together, but she was also very capable of working independently, designing and performing experiments. She picks up new techniques really fast and was able to clearly present her work in English, both orally and in writing. I got to know Suzanne as an intelligent young woman, enthusiastic and knowledgable about molecular biology and neuroscience. She has a fun and open personality and is easily liked by others, a recommendation for any team.
Jinte Middeldorp
I supervised Suzanne during a 6 month internship at Stanford University. She independently and successfully applied for funding to support her stay in Palo Alto. We worked well together, but she was also very capable of working independently, designing and performing experiments. She picks up new techniques really fast and was able to clearly present her work in English, both orally and in writing. I got to know Suzanne as an intelligent young woman, enthusiastic and knowledgable about molecular biology and neuroscience. She has a fun and open personality and is easily liked by others, a recommendation for any team.
Jinte Middeldorp
I supervised Suzanne during a 6 month internship at Stanford University. She independently and successfully applied for funding to support her stay in Palo Alto. We worked well together, but she was also very capable of working independently, designing and performing experiments. She picks up new techniques really fast and was able to clearly present her work in English, both orally and in writing. I got to know Suzanne as an intelligent young woman, enthusiastic and knowledgable about molecular biology and neuroscience. She has a fun and open personality and is easily liked by others, a recommendation for any team.
Credentials
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Certificate Project Management for Doctoral Research
Leiden UniversityNov, 2015- Oct, 2024 -
Certificate Time Management, Self Management
Leiden UniversityNov, 2015- Oct, 2024 -
Certificate Effective Communication
Leiden UniversitySep, 2015- Oct, 2024 -
Certificate Laboratory Animal Sciences - Article 9
Utrecht UniversityJan, 2014- Oct, 2024 -
Certificate Academic English for the Sciences
James Boswell InstituutFeb, 2012- Oct, 2024 -
Certificate Safe Microbiological Techniques I (VMT-I)
Utrecht UniversityNov, 2009- Oct, 2024
Experience
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CNCR, Center for Neurogenomics & Cognitive Research
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Netherlands
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Research Services
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1 - 100 Employee
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Postdoctoral Researcher iPSC models of FTD
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Jan 2022 - Present
Stem Cell-derived Disease Models of Frontotemporal Dementia• Supervisors: prof. dr. A.B. Smit, prof. dr. R.E. van Kesteren• Techniques: Primary fibroblast isolation from skin, Primary cell culture, iPSC(-derived) cell culture, Data-independent mass spectrometry-based quantitative proteomics, High through-put immunocytochemistry (cellomics), Bioinformatics, R programmingProject Lead on Industry-alliance Projects
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PhD Researcher Molecular Profiling in FTD
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Jun 2018 - Present
A Human Proteomics Disease Framework of Hereditary and Sporadic Frontotemporal Dementia• Supervisors: prof. dr. A.B. Smit, prof. dr. R.E. van Kesteren, prof. dr. J.C. van Swieten• Techniques: Data-independent mass spectrometry-based quantitative proteomics, Western blot, Immunohistochemistry, Bioinformatics, R programming, Python programmingPublications• Alzheimer's Research & Therapy 2023 - Clusters of co-abundant proteins in the brain cortex associated with fronto-temporal lobar degeneration• Acta Neuropathologica Communications 2022 - Proteomics of the dentate gyrus reveals semantic dementia specific molecular pathology• Acta Neuropathologica Communications 2022 - Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia• International Journal of Molecular Sciences 2021 - Molecular Pathways Involved in Frontotemporal Lobar Degeneration with TDP-43 Proteinopathy: What Can We Learn from Proteomics?• Brain 2020 - Somatic TARDBP variants as a cause of semantic dementia
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Erasmus MC
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Netherlands
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Hospitals and Health Care
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700 & Above Employee
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Research Assistant Immune Mediated Neuropathies
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Aug 2017 - May 2018
Immunity in viral-associated Guillain-Barré Syndrome • Supervisors: prof. dr. B. Jacobs MD, dr. H. Huizinga • Techniques: Flowcytometry, Cell culture Immunity in viral-associated Guillain-Barré Syndrome • Supervisors: prof. dr. B. Jacobs MD, dr. H. Huizinga • Techniques: Flowcytometry, Cell culture
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Mediquest
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Netherlands
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Research Services
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1 - 100 Employee
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Junior Project Researcher/Data-analyst
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Jun 2017 - May 2018
Projects:• National Database Physical Therapy for the Koninklijk Nederlands Genootschap Fysiotherapie• Consumer Quality Index Academic Hospitals• GP Quality Mentaal Beter• Waiting times in Specialized Medical CareTechniques: T-SQL, R, project management
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Project-assistent
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Feb 2017 - Jun 2017
Projects: Hospital Standardized Mortality Rate, Waitinglists in Specialized Medical Hospital Care, and Mental Health Care
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Netherlands Institute for Neuroscience
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Netherlands
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Research Services
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100 - 200 Employee
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PhD Researcher Neuroimmunology
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Mar 2015 - Feb 2016
Functional Characterization of Microglia in Normal Appearing Multiple Sclerosis (MS) Tissue. • Supervisors: dr. I. Huitinga and dr. J. Hamann • Techniques: Post-mortem human microglia and macrophage isolation, Primary cell culture, RNASeq, Bioinformatics, RT-qPCR, 8-color panel flow cytometry Publications • Nature Communications 2019 - Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes • Acta Neuropathologica Communications 2017 - Isolation of primary microglia from the human post-mortem brain: effects of ante- and post-mortem variables
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Stanford University
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United States
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Higher Education
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700 & Above Employee
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Visiting Research Intern (Honours Program MSc)
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Feb 2014 - Aug 2014
Rejuvenating and Regenerating Effects of Young Blood on Alzheimer's Mice • Supervisors: dr. J. Middeldorp, prof. dr. T. Wyss-Coray • Techniques: Cryohomogenization brain tissue, Cryostat sectioning brain tissue, RT-qPCR, Western Blot, Immunohistochemistry, Confocal laser scanning microscopy Publication JAMA Neurology 2016 - Preclinical Assessment of Young Blood Plasma for Alzheimer Disease Rejuvenating and Regenerating Effects of Young Blood on Alzheimer's Mice • Supervisors: dr. J. Middeldorp, prof. dr. T. Wyss-Coray • Techniques: Cryohomogenization brain tissue, Cryostat sectioning brain tissue, RT-qPCR, Western Blot, Immunohistochemistry, Confocal laser scanning microscopy Publication JAMA Neurology 2016 - Preclinical Assessment of Young Blood Plasma for Alzheimer Disease
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Department of Neuroscience and Pharmacology, Rudolf Magnus Institute for Neuroscience
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Utrecht, the Netherlands
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Intern (MSc)
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Feb 2013 - Jan 2014
The Immune-modulating Effects of Cannabinoids on Human Myeloid Cells • Supervisors: dr. L.D. de Witte, dr. M.P.M. Boks • Techniques: Primary cell culture, Post-mortem human microglial cell isolation, RT-qPCR, Flow cytometry, ELISA The Immune-modulating Effects of Cannabinoids on Human Myeloid Cells • Supervisors: dr. L.D. de Witte, dr. M.P.M. Boks • Techniques: Primary cell culture, Post-mortem human microglial cell isolation, RT-qPCR, Flow cytometry, ELISA
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Self-employed
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Leiden, the Netherlands
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Tutor
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Oct 2009 - Jan 2012
Tutoring Biology, Chemistry 1/2, Latin, Mathematics and Physics Tutoring Biology, Chemistry 1/2, Latin, Mathematics and Physics
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StudentsPlus Bijlessen
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Netherlands
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Primary and Secondary Education
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100 - 200 Employee
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Tutor
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Aug 2008 - Oct 2009
Tutoring Biology, Chemistry 1/2, Dutch, French, German, Latin, Mathematics and Physics Tutoring Biology, Chemistry 1/2, Dutch, French, German, Latin, Mathematics and Physics
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Education
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2012 - 2015
University of Utrecht
Master of Science (MSc), Neuroscience & Cognition - Experimental & Clinical Neuroscience Track -
2015 - 2017
Leidse Onderwijsinstellingen
Bahasa Indonesia -
2009 - 2012
University of Utrecht
Bachelor of Science (BSc), Biomedical Sciences -
2008 - 2009
University of Leiden
Life, Science & Technology -
2002 - 2008
Bonaventura College Mariënpoelstraat
Gymnasium diploma, Nature & Health with Chemistry 1/2, Greek language and Latin
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