Srinath Rangarajan

Senior Scientist at SQI Diagnostics
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Contact Information
us****@****om
(386) 825-5501
Location
Oblast Toronta, Kanada
Languages
  • English Znalost na úrovni rodilého nebo dvojjazyčného mluvčího
  • French Znalost umožňující omezenou práci
  • Tamil Znalost na úrovni rodilého nebo dvojjazyčného mluvčího
  • Hindi Znalost umožňující profesionální práci
  • Telugu Znalost umožňující omezenou práci

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Experience

    • Canada
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Scientist
      • 8/2020 - – do současnosti

    • Canada
    • Medical Equipment Manufacturing
    • 1 - 100 Employee
    • Senior Scientist
      • 1/2019 - 3/2020

    • Canada
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Scientist
      • 1/2016 - 12/2018

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Research Scientist II
      • 5/2014 - 4/2015

    • United States
    • Higher Education
    • 700 & Above Employee
    • Senior Fellow
      • 3/2012 - 1/2014

      Key Achievements• Developed modules and integrated colorimetric detection into low cost, prototype, point-of-care lateral flow membrane based devices• Invented novel methods for sample concentration. US Provisional Patent App. 61/808,106 (filed 4/3/2013) entitled: “Methods using evaporation in point of care diagnostic devices.” Inventors: S. Rangarajan, P. Yager, B. Lutz• Optimized rehydration of labels and signal enhancement and reduced assay times • Acquired considerable experience in product development, quality control and presented in regular technical meetings with collaborators (GE Global Research, PATH and others)

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Research Associate
      • 1/2008 - 9/2011

      Key Achievements• Invented an ultrasensitive, on-chip, isothermal amplification method for direct RNA species detection. US Provisional Patent App. PCT/US2014/067376 (June/2015) entitled “Direct detection of RNA by surface initiated enzymatic polymerization.” S. Rangarajan, M. Amiram, A. Hucknall and A. Chilkoti. Sentilus Inc., NC and Immucor, GA commercializing the technology. • Successfully led a four member team in a project to develop microRNA biomarkers for differentiating closely related lymphomas (Burkitt’s and Diffuse Large B Cell) using microRNA microarrays• Designed and performed experiments, data analysis and wrote progress reports• Developed DNA and protein microarray assays based on novel, non-fouling POEGMA polymer brushes and achieved picomolar limits of detection while assaying directly from cell lysates• Acquired experience in project management, teamwork, scientific grant writing and mentoring

    • United States
    • Higher Education
    • 700 & Above Employee
    • Graduate Research Associate
      • 2000 - 2007

      Key Achievements• Identified molecular pathways involved in drug resistance and adhesion by performing gene and protein expression studies on fungal biofilm fractions of C. albicans• Developed novel cryo-ToF SIMS to study transport of antifungal agents within biofilms of C. albicans• Characterized bio-active surfaces of novel dithiol molecules using XPS and ToF-SIMS• Developed chemometric models for spectral interpretation and image classification of ToF-SIMS data from proteins and other polymer coated surfaces• Presented talks and posters widely, and authored several publications

Education

  • University of Utah
    Doctor of Philosophy (PhD), Chemical Engineering
    2004 - 2007
  • University of Utah
    Master of Science (M.S.), Chemical and Fuels Engineering
    2000 - 2003
  • University of Madras
    Bachelor of Technology (B.Tech.), Chemical Engineering
    1996 - 2000

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