Sophie Acton
Associate Professor at MRC Laboratory for Molecular Cell Biology (LMCB), UCL- Claim this Profile
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Bio
Experience
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Laboratory for Molecular Cell Biology, UCL
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United Kingdom
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Higher Education
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1 - 100 Employee
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Associate Professor
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Oct 2015 - Present
London The Acton lab studies stromal/leukocyte interactions combining cell biology, image analysis and in vivo studies to investigate control of lymphoid tissue dynamics and anti-tumour immunity. Projects in the lab include investigating the mechanisms of lymph node expansion during inflammation, the communication between leukocytes and fibroblastic stroma in tumour microenvironments and the regulation of function controlled by mechanical tension.
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Cancer Research UK (CRUK)
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United Kingdom
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Non-profit Organizations
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700 & Above Employee
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Postdoctoral researcher
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Oct 2012 - Present
44 Lincoln's Inn Fields
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Henry Wellcome Post Doctoral Fellow
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Sep 2009 - Present
Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2. Immunity (impact factor: 20.59). 08/2012; DOI:10.1016/j.immuni.2012.05.022 Sophie E Acton, Jillian L Astarita, Deepali Malhotra, Veronika Lukacs-Kornek, Bettina Franz, Paul R Hess, Zoltan Jakus, Michael Kuligowski, Anne L Fletcher, Kutlu G Elpek, Angelique Bellemare-Pelletier, Lindsay Sceats, Erika D Reynoso, Santiago F Gonzalez, Daniel B Graham, Jonathan Chang… Show more Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2. Immunity (impact factor: 20.59). 08/2012; DOI:10.1016/j.immuni.2012.05.022 Sophie E Acton, Jillian L Astarita, Deepali Malhotra, Veronika Lukacs-Kornek, Bettina Franz, Paul R Hess, Zoltan Jakus, Michael Kuligowski, Anne L Fletcher, Kutlu G Elpek, Angelique Bellemare-Pelletier, Lindsay Sceats, Erika D Reynoso, Santiago F Gonzalez, Daniel B Graham, Jonathan Chang, Anneli Peters, Matthew Woodruff, Young-A Kim, Wojciech Swat, Takashi Morita, Vijay Kuchroo, Michael C Carroll, Mark L Kahn, Kai W Wucherpfennig, Shannon J Turley Show less
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Post doc
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2012 - 2013
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Dana-Farber Cancer Institute
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United States
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Hospitals and Health Care
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700 & Above Employee
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Post Doctoral Researcher
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Jul 2011 - Jul 2012
Maternity Leave
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Post Doctoral Researcher
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Sep 2008 - Jul 2011
Harvard Medical School Department of Cancer Immunology and AIDS
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Cancer Research UK (CRUK)
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United Kingdom
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Non-profit Organizations
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700 & Above Employee
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Graduate Student
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Sep 2004 - Sep 2008
Supervised by Dr Erik Sahai Studied mechanisms of metastasis in models of melanoma.
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Takeda Oncology
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Placement student
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2002 - 2003
Cambridge, United Kingdom Development of high-throughput assays for screening lead compounds.
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Education
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University College London, U. of London
Ph.D. Biochemistry, Mechanisms of cancer cell motility -
University of Bath
MPharmacol, Pharmacology