Sophie Acton

Associate Professor at MRC Laboratory for Molecular Cell Biology (LMCB), UCL
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Contact Information
us****@****om
(386) 825-5501
Location
London, England, United Kingdom, UK

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Experience

    • United Kingdom
    • Higher Education
    • 1 - 100 Employee
    • Associate Professor
      • Oct 2015 - Present

      London The Acton lab studies stromal/leukocyte interactions combining cell biology, image analysis and in vivo studies to investigate control of lymphoid tissue dynamics and anti-tumour immunity. Projects in the lab include investigating the mechanisms of lymph node expansion during inflammation, the communication between leukocytes and fibroblastic stroma in tumour microenvironments and the regulation of function controlled by mechanical tension.

    • United Kingdom
    • Non-profit Organizations
    • 700 & Above Employee
    • Postdoctoral researcher
      • Oct 2012 - Present

      44 Lincoln's Inn Fields

    • Henry Wellcome Post Doctoral Fellow
      • Sep 2009 - Present

      Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2. Immunity (impact factor: 20.59). 08/2012; DOI:10.1016/j.immuni.2012.05.022 Sophie E Acton, Jillian L Astarita, Deepali Malhotra, Veronika Lukacs-Kornek, Bettina Franz, Paul R Hess, Zoltan Jakus, Michael Kuligowski, Anne L Fletcher, Kutlu G Elpek, Angelique Bellemare-Pelletier, Lindsay Sceats, Erika D Reynoso, Santiago F Gonzalez, Daniel B Graham, Jonathan Chang… Show more Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2. Immunity (impact factor: 20.59). 08/2012; DOI:10.1016/j.immuni.2012.05.022 Sophie E Acton, Jillian L Astarita, Deepali Malhotra, Veronika Lukacs-Kornek, Bettina Franz, Paul R Hess, Zoltan Jakus, Michael Kuligowski, Anne L Fletcher, Kutlu G Elpek, Angelique Bellemare-Pelletier, Lindsay Sceats, Erika D Reynoso, Santiago F Gonzalez, Daniel B Graham, Jonathan Chang, Anneli Peters, Matthew Woodruff, Young-A Kim, Wojciech Swat, Takashi Morita, Vijay Kuchroo, Michael C Carroll, Mark L Kahn, Kai W Wucherpfennig, Shannon J Turley Show less

    • Post doc
      • 2012 - 2013

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Post Doctoral Researcher
      • Jul 2011 - Jul 2012

      Maternity Leave

    • Post Doctoral Researcher
      • Sep 2008 - Jul 2011

      Harvard Medical School Department of Cancer Immunology and AIDS

    • United Kingdom
    • Non-profit Organizations
    • 700 & Above Employee
    • Graduate Student
      • Sep 2004 - Sep 2008

      Supervised by Dr Erik Sahai Studied mechanisms of metastasis in models of melanoma.

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Placement student
      • 2002 - 2003

      Cambridge, United Kingdom Development of high-throughput assays for screening lead compounds.

Education

  • University College London, U. of London
    Ph.D. Biochemistry, Mechanisms of cancer cell motility
    2004 - 2008
  • University of Bath
    MPharmacol, Pharmacology
    2000 - 2004

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