Sophie Naud

Senior Research Associate, Biomedical Engineering at Selux Diagnostics, Inc
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Contact Information
us****@****om
(386) 825-5501
Location
Brookline, Massachusetts, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Research Associate, Biomedical Engineering
      • Oct 2023 - Present

    • United States
    • Higher Education
    • 700 & Above Employee
    • Researcher, Kyriakides Laboratory
      • Jan 2022 - May 2023

      Senior Thesis Project: Nanoparticles for sustained drug-release hydrogel systems to improve diabetic wound healing Developed and characterized drug-encapsulated polymeric nanoparticles for sustained delivery of DMOG and DFX from therapeutic hydrogels to improve diabetic wound healing. Project: Improving diabetic wound healing using cell-derived ECM enriched with engineered high-affinity PDGF Created algorithms to efficiently quantify immune cell population and angiogenesis (number and area of mature vessels) of 375+ histology images as a metric of wound healing using ImageJ and the ImageJ Macro language (IJM). Show less

    • United States
    • Medical Practices
    • 100 - 200 Employee
    • Research Assistant, Gutkind Laboratory
      • Jun 2022 - Aug 2022

      Successfully established an in vitro system reflecting a genetically engineered mouse model for HPV+ oral cancer via lentiviral transduction. Confirmed expression of cancer-associated proteins E6, E7, and YAP1. Analyzed immune response in malignant transformation via quantification of cell populations in murine tongue epithelia and explored the chemotactic response of monocytes. Successfully established an in vitro system reflecting a genetically engineered mouse model for HPV+ oral cancer via lentiviral transduction. Confirmed expression of cancer-associated proteins E6, E7, and YAP1. Analyzed immune response in malignant transformation via quantification of cell populations in murine tongue epithelia and explored the chemotactic response of monocytes.

    • United States
    • Hospitals and Health Care
    • Fellow
      • Sep 2021 - May 2022

      Collaborated with Yale physicians and Helix team to develop a miniaturized external defibrillator, Minfib, to address challenges in cardiac arrest response time by designing a more accessible and portable device Optimized prototype design and produces competitor and market analyses for product developmental Collaborated with Yale physicians and Helix team to develop a miniaturized external defibrillator, Minfib, to address challenges in cardiac arrest response time by designing a more accessible and portable device Optimized prototype design and produces competitor and market analyses for product developmental

    • United States
    • Biotechnology Research
    • Chief Administrative Officer
      • Feb 2020 - May 2022

      Negotiated contracts of up to $30,000 with academic and industrial institutions, analytical testing labs, and startups (e.g. GRAIL, MIT, Genentech, Twist Bioscience) on an international scale on behalf of student-run startup biotech company Collaborated with legal advisors, produces financial projections, ensures financial legal compliance of a 501(c)(3) organization, and leads efforts to amend company bylaws to ensure compensation for members Spearheaded consumer research efforts to expand customer base and maintain current consumer relationships Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Assistant, Saltzman Laboratory
      • Jun 2021 - Aug 2021

      Project: Optimizing polymeric nanoparticles for in-utero gene editingFormulated a library of polymeric nanoparticles (NPs) with varying polymer base, size, surfactant, and level of PEGylation; characterized stability, surface potential, and polydispersity index with dynamic light scatteringTreated human embryonic kidney cells with NPs and analyzed cellular uptake with flow cytometryInjected fetal mice with NPs to analyze NP biodistribution patterns with cryosectioning and confocal microscopyPresented to faculty on various relevant research papers and produced a journal-style report on findings Show less

    • Project Manager, e-NABLE
      • Sep 2020 - Jun 2021

      Partnered with local clinics to provide free and low-cost 3D-printed prosthetic hands to locals in needSuccessfully created a functional prosthetic hand and obtained Fabrication and Assembly quality certifications

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Pharmacology Research Assistant, Chou Lab
      • Sep 2020 - Dec 2020

      Assisted in the research and development of Neuroene Therapeutics’ patented pharmaceutical treatment for mitochondrial disorders; tested novel vitamin K analogs on zebrafish expressing symptoms

    • 3D Printing Intern, Neuro-X Lab
      • Sep 2020 - Dec 2020

      Created two prosthetic hands on an independent project for e-NABLE while learning the ins and outs of 3D printingReport published on the Neuro-X website

  • Absolute Mortgage, Inc.
    • Irvine, California, United States
    • Administrative Assistant
      • Mar 2020 - Aug 2020

    • United States
    • Performing Arts
    • 1 - 100 Employee
    • Community Development Assistant
      • Sep 2017 - Jun 2019

Education

  • Yale University
    BS and MS in Biomedical Engineering, Graduated magna cum laude (3.97 GPA) with Distinction in the major
    2019 - 2023
  • Professional Performing Arts High School
    Graduated as Valedictorian with High Honors
    2015 - 2019

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