Sarah Lucas
Medical Student & Clinical Researcher at Georgetown University School of Medicine- Claim this Profile
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Bio
Experience
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Georgetown University School of Medicine
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United States
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Higher Education
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200 - 300 Employee
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Medical Student & Clinical Researcher
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Aug 2019 - Present
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Oak Ridge National Laboratory
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United States
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Research Services
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700 & Above Employee
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Post-Bachelor's Research Associate
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Oct 2018 - Jun 2019
Engineered protein sample environments amenable to simultaneous FRET and SANS measurements. Engineered protein sample environments amenable to simultaneous FRET and SANS measurements.
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Premier Surgical Associates
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United States
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Medical Practices
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1 - 100 Employee
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Medical Scribe
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Jun 2018 - Dec 2018
Served as a surgical scribe for Dr. Greg Midis, a general surgeon specializing in oncology and colorectal surgery. I was responsible for constructing HPIs and transcribing physician notes. Served as a surgical scribe for Dr. Greg Midis, a general surgeon specializing in oncology and colorectal surgery. I was responsible for constructing HPIs and transcribing physician notes.
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North Carolina State University
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United States
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Higher Education
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700 & Above Employee
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Teaching Assistant
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Jan 2018 - May 2018
BME 362 is a weekly, 4 hour lab centered around the characterization of biomaterials. BME 362 is a weekly, 4 hour lab centered around the characterization of biomaterials.
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UHP Senior Capstone Research Thesis
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Aug 2016 - Dec 2017
I completed my NC State Honors Program Capstone thesis in conjoint with my mentors Matt Cuneo (SNS/ORNL) and Bob London (NIEHS). The goal was to generate a comprehensive model of the XRCC1 / DNA Ligase III-a Base Excision Repair complex using both X-ray crystallography and Small Angle Scattering techniques. I worked to develop and subsequently optimize protocols for expression, purification, complexation & crystallization. I also performed XRD, SAXS, & SANS on my samples. I completed my NC State Honors Program Capstone thesis in conjoint with my mentors Matt Cuneo (SNS/ORNL) and Bob London (NIEHS). The goal was to generate a comprehensive model of the XRCC1 / DNA Ligase III-a Base Excision Repair complex using both X-ray crystallography and Small Angle Scattering techniques. I worked to develop and subsequently optimize protocols for expression, purification, complexation & crystallization. I also performed XRD, SAXS, & SANS on my samples.
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Oak Ridge National Laboratory
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United States
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Research Services
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700 & Above Employee
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Summer Intern
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May 2016 - Aug 2016
I worked under my mentor, Matt Cuneo, along side his post-doc Le Li on two different projects. The first entailed inserting a four protein trans-membrane complex into self-assembling nano-discs to conduct ATP kinetic assays to probe the metabolic differences between Wild type and Mutant type Periplasmid Binding Protein (PBP) under both apo and saturated ligand conditions. This project is currently progressing to the publication phase. The second project entailed crystalizing the constitutive complex between XRCC1 and DNA Ligase-IIIa. This project remains ongoing. Both projects entailed extensive cellular growth and purification. While at ORNL, I also attended the 5th International Conference on Diffraction Biology, which was hosted in Knoxville, TN. Show less
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North Carolina State University
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United States
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Higher Education
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700 & Above Employee
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Resident Advisor
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Aug 2015 - Jan 2016
* Took part in rigorous leadership & diversity training courses and seminars * Developed interpersonal skills * Conflict Management, Organization, Multitasking, and Team Work were all critical skills that I developed over the course of this experience. * Took part in rigorous leadership & diversity training courses and seminars * Developed interpersonal skills * Conflict Management, Organization, Multitasking, and Team Work were all critical skills that I developed over the course of this experience.
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Oak Ridge National Laboratory
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United States
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Research Services
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700 & Above Employee
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Laboratory Researcher
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May 2015 - Aug 2015
I worked under my mentors, Dr. Chris Stanley & Dr. Hugh O’Neill, in conjoint with Dr. Richard Kriwacki’s lab at St. Jude’s Children’s Research Hospital in order to procure deuterated protein samples for SANS neutron analysis of transient conformational states adopted by p27kip, a disordered protein that is linked to several common oncogenes such as NRTKs, Brc-Able, & Src. I gained valuable proficiency in various Induction, Transformation, and Purification techniques as well as several laboratory analytical tools such as SDS-Page and Absorbance Spectrums. I also attended some of the National Neutron School lectures, and presented my work in both keynote and poster formats. Show less
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UT Medical Center
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United States
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Hospitals and Health Care
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700 & Above Employee
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Laboratory Research Assistant
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May 2013 - May 2014
I conducted research in Dr. Berthelier's lab pertaining to the organic secretion of nano-particles using anaerobic, thermophilic bacteria. I gained valuable experience in a broad range of laboratory techniques including dynamic light scattering, western blots, and spectrophotometry. According to the Dean of the medical school, I was the youngest employee to ever be on payroll. I conducted research in Dr. Berthelier's lab pertaining to the organic secretion of nano-particles using anaerobic, thermophilic bacteria. I gained valuable experience in a broad range of laboratory techniques including dynamic light scattering, western blots, and spectrophotometry. According to the Dean of the medical school, I was the youngest employee to ever be on payroll.
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Education
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Georgetown University School of Medicine
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North Carolina State University
Bachelor of Science - BS, Biomedical & Health Sciences Engineering -
University of North Carolina at Chapel Hill
Bachelor of Science - BS, Biomedical & Health Sciences Engineering -
The Webb School of Knoxville
High school Diploma