Experience

Experimental Drug Development Centre (EDDC)

• Singapore
• Research
• 1 - 100 Employee

• Research Manager

  • Apr 2021 - Present

  + Manage the High Throughput Phenomics Platform. + Develop High Content Imaging and Cell-based Assay solutions for biologically targetable candidates. Keen on: + Discussing collaborations for portfolio projects that hold promise for Preclinical Development Candidates and perhaps Clinical Proof of Concepts or potential Spin-off companies. + Engaging in partnership deals with biotech companies and the pharma industry. + Discussing viable public-funding options for qualified projects. Show less



Genome Institute of Singapore

• Singapore
• Research Services
• 200 - 300 Employee

• Assistant Platform Manager @ CHiP-GIS

  • Apr 2014 - Apr 2021

  + Played a central role in establishing the CHiP-GIS drug discovery platform + Helped establish Stronghold Diagnostics, a National COVID-19 Testing Facility + Authored and implemented ISO13485:2016 Medical Devices quality management system + Developed a novel anti-HBV drug discovery framework + Consulted numerous drug screening projects + Fostered collaborations between research groups in academia, clinics, and indusry + Organised technology training workshops for the scientific community in Singapore + Implemented robust systems to track platform activities and fine tune for operational efficiency + Led community outreach efforts to educate and inspire Singapore’s younth and general public • To manage the Center for High-throughput Phenomics platform • To plan and manage project activities to meet service quality, timeline, and budgetary goals • To engage with scientific community for screening projects and collaborations • To maintain and implement improvements to laboratory management system • To identify and resolve issues impacting team alignment Show less



inStem - Institute for Stem Cell Biology and Regenerative Medicine

• Bangalore, India

• Project Coordinator

  • Feb 2012 - Apr 2014

  + Supervized development of the entire research infrastructure of InStem + Implemented critical support systems (Safety, Procurement, Inventory, Technology Maintenance) + Chaired the research infrastructure taskforce + Managed an active R&D space with over 100 research staff + Organised the 2013 All India Cell Biology Conference (fund-raising and event management) • Overall laboratory administration and operations management • Point-of-contact for negotiations and implementation of new technologies • To coordinate with Architects, Engineers (Civil, IT, and Electrical), Technology Experts, Purchase Agents, Accountants, Laboratory Support, Inventory, Hospitality, and Security Detail Show less



UC San Diego

• United States
• Higher Education
• 700 & Above Employee

• Staff Research Associate III

  • Oct 2009 - Sep 2011

  ► Designed and executed studies to understand the molecular mechanisms driving mitochondrial autophagy. ► Extensively studied the role of Bnip3, a BCL-2 family protein, in mitochondrial biogenesis in the context of adult mice cardiomyocytes under stress condition like simulated ischemia/reperfusion and hypoxia. ► Characterized cardiac stem cells harvested from adult mice hearts for their capacity to proliferate and differentiate when treated with inhibitors used in cancer chemotherapy. ► Developed a number of crucial adenoviral expression tools for easy detection in subcellular localization studies. ► Managed smooth transition of the whole research team to a new laboratory location and aided in expansion of the research team. ► Contributed and authored publications in peer-reviewed journals. ► Trained and supervised postdoctoral fellows, graduate students, and staff with many aspects of their projects and duties. ► Have undertaken many troubled projects and carried them until they became publications. ► Authored at least 2 presentations at the AHA 2009, and 2010 scientific sessions. Show less



SDSU Research Foundation

• United States
• Higher Education
• 400 - 500 Employee

• Molecular Biology Specialist

  • Mar 2008 - Sep 2009

  ► My research efforts were focused on understanding the effects of Doxorubicin, a chemotherapeutic drug for leukemia known to cause cardiotoxicity, on stem cells harvested from juvenile mice hearts. ► Contributed to delineation the signaling pathways of BCL-2 family proteins, MCL-1 and Bnip3, in the control of mitochondrial transition pore opening that confers cardioprotective effects by upregulating autophagy in mice cardiomyocytes. ► Designed a novel sandwich ELISA study that utilizes cDNA to measure the proliferative capacity of cardiac stem cells. ► Resolved troubled and abandoned projects left unsolved by predecessors. ► Engaged several projects simultaneously. ► Accomplished tasks on aggressive timelines to meet grant deadlines. ► Trained and supervised post-docs, graduate students, and technicians on a regular basis. ► Contributed significant amounts of data to coauthor in peer-reviewed journals. ► Authored at least 3 presentations at the AHA 2008 scientific sessions. Show less



University of Missouri-Columbia

• United States
• Higher Education
• 700 & Above Employee

• Research Assistant

  • Aug 2004 - Mar 2008

  Signal Transduction of an extracellular nucleotide G Protein-coupled receptor, P2Y2R, in the formation of Tight junction and in Smooth Muscle Cell Phenotypic Modulation Signal Transduction of an extracellular nucleotide G Protein-coupled receptor, P2Y2R, in the formation of Tight junction and in Smooth Muscle Cell Phenotypic Modulation